Towards an ontology for psychosis

There is a pressing need for data interoperability in neuroscience especially in mental health and psychiatric research. Heterogeneity of data in the domain is a combination of a plethora of assessment methods and two clinical classification systems with no formal method of interconversion. Ontologies with their formal logical basis have been successfully used to achieve interoperability in other fields of biology. We discuss the need for an ontology in the domain of psychosis and propose a methodology for building such an ontology. We outline the various factors that are important for building a unifying ontology and how this might serve as a good start for building better classification systems in psychiatry.     

The influence of horizontal velocity on interlimb symmetry in normal walking

Changes in horizontal velocity (HV) are known to influence many biomechanical characteristics of human locomotion. The purpose of the present study was to investigate this phenomenon with respect to the interlimb symmetry of walking in a normal population. Peak and temporal ground reaction force data from both feet of 20 able-bodied males were collected at each of three relative velocity conditions (slow, normal and fast). These data were analyzed using of a series of 2 x 3 repeated measures ANOVAs, which revealed a high degree of interlimb (bilateral) symmetry across HV conditions despite significant intralimb (unilateral) changes. In contrast to this primary finding were two significant interaction effects for the stance time and peak vertical force at push-off measures respectively. These interactions indicated greater asymmetries at the slow HV condition with a trend toward improved symmetry at higher velocities. Although these results may provide some theoretical insight into the underlying nature of symmetry in gait, their overall magnitude does not seem to invalidate the current widespread use of symmetry assumptions in clinical and research settings today.     

The logic of obligation, ‘better’ and ‘worse’

Research for this paper was supported by a grant from the National Endowment for the Humanities, FT-33794. I am grateful to an anonymous referee of this journal for remarks on an earlier version of this paper.     

Lateral cerebral differences in the deaf in response to linguistic and nonlinguistic stimuli

Groups of deaf subjects, exposed to tachistoscopic bilateral presentation of English words and American Sign Language (ASL) signs, showed weaker right visual half-field (VHF) superiority for words than hearing comparison groups with both a free-recall and matching response. Deaf subjects showed better, though nonsignificant, recognition of left VHF signs with bilateral presentation of signs but shifted to superior right VHF response to signs when word-sign combinations were presented. Cognitive strategies and hemispheric specialization for ASL are discussed as possible factors affecting half-field asymmetry.     

Vibrotactile adaptation on the face

Threshold amplitude for vibration is elevated if testing is preceded by extended exposure to a vibratory adapting stimulus of appropriate amplitude and frequency. This phenomenon, previously studied almost exclusively on the hand, is here shown for the first time to occur on the face as well. Adaptation is then used analytically to determine that the two-branched threshold-versus-frequency function obtained on the face by Verrillo and Ecker (1977) represents the activity of two distinct mechanisms. Action spectra of vibrotactile adaptation reveal the presence of both mechanisms even in subjects whose unadapted threshold function (like that reported by Barlow, 1987) shows no sign of duplexity. Finally, the data suggest that on the face (unlike the hand), cross-channel adaptation may occur at high adapting amplitudes.     

Normative Conflicts and The Logic of 'Ought'

On the face of it, normative conflicts are commonplace. Yet standard deontic logic declares them to be logically impossible. That prompts the question, What are the proper principles of normative reasoning if such conflicts are possible? This paper examines several alternatives that have been proposed for a logic of ‘ought’ that can accommodate normative conflicts, and finds all of them unsatisfactory as measured against three criteria of adequacy. It then introduces a new logic that does meet all three criteria, and so allows for the possibility of genuine normative conflicts.     

Neighborhoods for Entailment

This paper presents a neighborhood semantics for logics of entailment. It begins with a minimal system Min that expresses the most fundamental assumptions about the entailment relation, and continues by examining various extensions that reflect further assumptions that might be made about entailment. This leads first to the logic B that is the basic relevant logic, and then to more powerful systems. All of these logics are proved to be sound and strongly complete. With B the neighborhood semantics meets the Routley–Meyer relational semantics for relevant logic; these connections are examined. The minimal and basic entailment logics are shown to have the finite model property, and hence to be decidable.