The Ethics of Type 1 Diabetes Prediction and Prevention Research

There are approximately one million cases oftype 1 diabetes in the US, and the incidenceis increasing worldwide. Given that two-thirdsof cases present in childhood, it is criticalthat prediction and prevention research involvechildren. In this article, I examine whethercurrent research methodologies conform to theethical guidelines enumerated by the NationalCommission for the Protection of Human Subjectsof Biomedical and Behavioral Research, andadopted into the federal regulations thatprotect research subjects. I then offer twopolicy recommendations to help researchersdesign studies that conform to these ethicalrequirements.     

Bertrand Russell in His Nineties: Aging and the Problem of Biography

Bertrand Russell, one of the twentieth century's leading philosophers, lived to be ninety-eight, spending his last decade as a vigorous and often unpopular political activist. His generally sympathetic biographers tend to view this last decade through the prism of senility, but the only justification for this judgment would appear to be the objective fact of Russell's age. Almost identical behaviors from his younger years are never attributed to mental shortcomings. The treatment of Russell suggests that biographers are susceptible to powerful, distorting, and fictive predispositions as they shape their subjects' later years.     

Attentional blink for color

Colored letters were presented by means of rapid serial visual presentation (RSVP). Two letters (T1 and T2) were targets that required a speeded (T1) or delayed (T2) response. T1 was shown on half of the trials. Two tasks were performed in the experimental conditions. Task 1 required a discrimination between 2 letters (when T1 was shown) or an indication that T1 was absent. In Experiment 1, Task 2 was to detect the presence of a unique color in the RSVP stream (e.g., green in a stream of alternating red and gray). In Experiment 2, Task 2 was to report the color of the first colored letter to appear in the RSVP stream. The lag between T1 and T2 in the RSVP stream was manipulated. Accuracy of color reports in Task 2 was poor at shorter lags and improved as the lag was lengthened in both experiments, demonstrating an attentional blink for chromatic information. Theoretical implications of the results are discussed.     

The Mozart Effect: An Artifact of Preference

The "Mozart effect" reported by Rauscher, Shaw, and Ky (1993, 1995) indicates that spatial-temporal abilities are enhanced after listening to music composed by Mozart. We replicated and extended the effect in Experiment 1: Performance on a spatial-temporal task was better after participants listened to a piece composed by Mozart or by Schubert than after they sat in silence. In Experiment 2, the advantage for the music condition disappeared when the control condition consisted of a narrated story instead of silence. Rather, performance was a function of listeners' preference (music or story), with better performance following the preferred condition.     

Induction with cross-classified categories

One of the main functions of categories is to allow inferences about new objects. However, most objects are cross-classified, and it is not known whether and how people combine information from these different categories in making inferences. In six experiments, food categories, which are strongly crossclassified (e.g., a bagel is both a bread and a breakfast food), were studied. For each food, the subjects were told fictitious facts (e.g., 75% of breads are subject to spoilage from Aspergillus molds) about two of the categories to which it belonged and then were asked to make an inference about the food (e.g., how likely is a bagel to be subject to spoilage from Aspergillus molds?). We found no more use of multiple categories in these cases of cross-classification than in ambiguous classification, in which it is uncertain to which category an item belongs. However, some procedural manipulations did markedly increase the use of both categories in inferences, primarily those that focused the subjects’ attention on the critical feature in both categories.     

Dimensional Personality Traits Broadly and Selectively Associated with Normative Externalizing Behavior

This study aimed to distinguish personality traits that are widely associated with several types of externalizing behaviors from personality traits that are more selectively associated with one or only a few specific types of externalizing behavior. A wide range of externalizing behaviors (e.g. alcohol and drug use, risky driving, aggressive acts, sexual promiscuity and relationship infidelity, academic misconduct) typical among an undergraduate population (N?=?257) were examined along with a range of personality traits measured using the Section III personality model for the DSM-5. We found that externalizing behavior was best associated with the domain level trait Antagonism and, to a lesser degree, Disinhibition. Antagonism’s association with problematic behavior was primarily accounted for by the facet trait Deceitfulness. Deceitfulness was found to be associated with a wide range of behaviors including relationship infidelity, theft, aggressive acts, and drug and alcohol use. Associations between Disinhibition and problem behavior, especially risky driving and poor work or school performance, were best accounted for by the Irresponsibility facet, as opposed to the Impulsivity or Distractibility facet traits. This comprehensive multivariate approach is important for a more complete understanding of the complex relationship that exists between personality traits and externalizing behavior. A better understanding of factors precipitating externalizing behavior could ultimately lead to an increased ability to target interventions to individuals most susceptible to engage in problematic behavior.