Verb Comprehension Deficits in Probable Alzheimer's Disease

Studies of lexical comprehension in probable Alzheimer's disease (pAD) have focused almost exclusively on nouns. In the following preliminary study, we examined whether lexical comprehension for verbs is also impaired in 25 pAD patients. The semantic meaning of motion verbs, cognition verbs, and perception verbs was assessed with a triadic comparison task. Structural meaning associated with these verbs was evaluated by asking the patients to judge the coherence of sentence frames that accept these verbs naturally or awkwardly. We found that pAD patients are significantly impaired at identifying semantic relations among verbs. pAD patients also encountered significantly more difficulty judging the coherence of sentences than control subjects. Correlation and regression analyses demonstrated that semantic characteristics of verbs are projected from the verbs' sentence frames in control subjects, but there was minimal evidence for such a structural–semantic relationship in pAD. We consider several possible explanations for our preliminary observations of an impairment that has consequences for processing both semantic and structural aspects of verb meaning.     

Social attitudes of schizophrenics

The Wilson-Patterson Conservatism Scale was given to 34 schizophrenic and 34 non-schizophrenic patients in a Dutch mental hospital. The absence of liberal-scoring schizophrenics was interpreted as consistent with the theory that the social withdrawal seen in chronic schizophrenia represents a strategy for coping with stimulus overload. Internal consistency analysis of C scale performance indicated that this test might be used to assess thought disorder in much the same way as the Bannister and Fransella Grid Test, but a great deal more economically. Furthermore, the questionnaire permits a more detailed examination of the source of inconsistency than does the repertory grid method.     

Alcohol breath tests: Criterion times for avoiding contamination by “mouth alcohol”

Using either a gas chromatography or an infrared absorption technique, series of blood alcohol concentrations (BACs) determined by breath tests were obtained from human subjects immediately subsequent to their having only oral contact with beverages ranging in ethyl alcohol concentration from 4% to 95% +. Times for total dissipation of mouth alcohol residuals to a level of practical nonsignificance ranged from 10 to 19 min. Dissipation rates were an inverse and approximately exponential function of the ethyl alcohol concentration of the beverage and were greatly shortened by rinsing the mouth with warm (34°C) water prior to testing. The results are discussed in terms of their relevance to the methodology of a number of research studies employing BAC breath-testing equipment.     

An examination of the effect of six types of error perturbation on fifteen clustering algorithms

An evaluation of several clustering methods was conducted. Artificial clusters which exhibited the properties of internal cohesion and external isolation were constructed. The true cluster structure was subsequently hidden by six types of error-perturbation. The results indicated that the hierarchical methods were differentially sensitive to the type of error perturbation. In addition, generally poor recovery performance was obtained when random seed points were used to start theK-means algorithms. However, two alternative starting procedures for the nonhierarchical methods produced greatly enhanced cluster recovery and were found to be robust with respect to all of the types of error examined.