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Simeoni S Biselli R D'Amelio R Rocca B Lattanzio S Mucci L Davì G Patacchioli FR 《Stress (Amsterdam, Netherlands)》2011,14(3):282-289
Few studies have assessed the effects of stress on in vivo platelet activation. In the present study, hypobaric hypoxia induced by rapid decompression during high-altitude simulated flight in a hypobaric chamber was used to evaluate the effects of environmental stress on salivary cortisol and urinary thromboxane metabolite (TXM) excretion, a noninvasive marker of in vivo platelet function. Twenty-one male aviators (mean ± SD age = 36 ± 7 years) experiencing hypoxia by removing their oxygen mask for 4-5 min during a simulated flight to 25,000 ft (7,620 m; pO(2) = 59.17 mmHg) and a matched control group of thirteen flying instructors wearing oxygen masks during the challenge, were studied. Hypobaric hypoxia induced a transient significant increase (P < 0.001) in the aviators' salivary cortisol concentration; the overall pattern of diurnal cortisol fluctuation was maintained in both groups. Urinary TXM showed a significant ~30% reduction (P < 0.01) after the chamber session in aviators exposed to hypobaric hypoxia, but not in controls. A significant inverse correlation was found between salivary cortisol and urinary TXM in aviators (r = - 0.64, P = 0.0015). Salivary cortisol was a significant predictor (P < 0.001) for urinary TXM concentrations in aviators. In conclusion, here we observed that an acute stress-induced salivary cortisol increase was associated with reduced urinary thromboxane biosynthesis, providing the first indirect evidence for an inhibitory effect of acute stress on in vivo platelet function. 相似文献
53.
Mild cognitive impairment (MCI) is a heterogeneous condition characterized by the presence in an otherwise healthy elderly
individual of cognitive deficits involving specific domains in the absence of significant functional impairments. Reports
indicate that prospective memory (PM), that is, the ability to remember to execute delayed intentions, is impaired in individuals
with MCI. The present review discusses the current debate in the literature on PM functioning in MCI by focusing on the relationship
between prospective retrieval and retrospective memory functioning. Analysis of the reported evidence revealed that both the
prospective component and the retrospective component of PM can be impaired in MCI. Declarative memory dysfunction may account
for the retrospective memory impairment, while either reduced executive abilities or a deficit of reflexive mechanisms could
explain the prospective component impairment. 相似文献
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Gabriele Buccola, since his untimely death, often has been mentioned as the first Italian psychologist who developed a strict program of laboratory research. Buccola, a Sicilian of Albanian ancestry, is a "case" in the history of Italian psychology. A self-taught positivist, he established a relation with the major representatives of the European positivism. Kraepelin mentions him as one of the precursors of his project of applying experimental psychology to psychopathology. Buccola actually carried out research on the psychological, chemical-biological, and psychopathological "modifiers" of reaction times, following an experimental program dealing mainly with the differential study both of basic and superior psychological processes, with mental hygiene ends. Historians of psychology agree in considering Buccola the first Italian laboratory psychologist to plan a program of research that was close to European psychological experimentalism.The present article, starting from an outline of Buccola's role in the rising Italian scientific psychology, recontextualizes his experimentalism in an international sphere. This operation, which is carried out through a careful survey of Buccola's entire production-both theoretical and more properly scientific-is based on the search of the Darwinian, Spencerian, and Haeckelian evolutionist themes emerging from Buccola's program of research-a program that was influenced by the variegated European experimental panorama and characterized by the vision of science as a knowledge capable of transforming the nature of man and of society. 相似文献
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Giovanni Codevilla 《宗教、国家与社会》2013,41(2):113-138
Abstract According to its constitution the Russian Federation is a secular state in which all religious associations are equal before the law. The constitution also guarantees freedom of religious choice and practice. Federal legislation, as well as the legislation of the republics, should be in accordance with these clearly formulated principles. Many provisions in the federal law on religion of 1997, however, are in conflict with them. Moreover, in practice the statement in the preamble to that law regarding the historical role of Orthodoxy and that of other ‘traditional religions’ is arbitrarily interpreted to justify a privileged position for Orthodoxy and to some extent for Islam, Judaism and Buddhism. The ‘secularity’ of a state does not entail the marginalisation of religion. A secular state should take account of the historical role and importance of each religion. The Russian state may legitimately award Orthodoxy a position of primus inter pares and privileges of honour in comparison with other religions on the basis of proportionality. These should not, however, take the form of legal advantages. Orthodoxy can perfectly well play the role of ‘official’ religion, but it should not be a ‘state’ religion. It would be advisable to establish a system of bilateral agreements between each religious association and the state and to create a fiscal system that allowed citizens who declare that they belong to a given religious faith to devote part of their taxes to the financial support of that faith. 相似文献
58.
Giovanni Piumatti Laura Pipitone Angela Maria Di Vita Delia Latina Emanuela Rabaglietti 《Journal of Adult Development》2014,21(1):1-12
We explored the phenomenon of the transition to adulthood, focusing on how young people cope with various developmental tasks in relation to their expectations, future projects, fears and indecision in two Italian regional areas characterized by different trends in youth employability, higher educational attainment and family formation process. We measured self-perceived adulthood, self-reported satisfaction, independence, perceived support regarding personal relationships and practical and economical issues, personal projections and future life’s choices. We also explored the perception of self-fulfillment for the future concerning personal goals in life, such as in the spheres of work, studies and economic autonomy together with expectations for the quality of personal relationships. One hundred and sixty nonworking university students (M age = 22.6; SD = 2.77; range = 19–35) from the Universities of Turin and Palermo took part in this study. Sub-groups differed on self-perceived adulthood, self-reported satisfaction, independence, perceived support and self-fulfillment. Psychological and economic independence from the family of origin was most perceived by the participants from Turin who reported a higher degree of satisfaction regarding their choice of studies and their future perspective of self-fulfillment at work. Young people from Palermo highlighted personal relationships as an important source of perceived support. 相似文献
59.
In three experiments, we tested the hypothesis that activation of multiplication operand nodes (e.g., 3 and 8) can occur through presentation of their product (e.g., 24). In Experiments 1 and 2 we found activation of the operands when the product was presented as a cue in a number-matching task. In Experiment 3, activation also occurred in a parity-matching task, where the product (24) was not relevant to the parity matching on its operands (3 and 8). We concluded that bidirectional links exist among the operands and their product for multiplication problems and these links can be activated in a purely stimulus-driven manner. We suggest this may constitute the basis for the solution of simple divisions by mediation through the complementary multiplication facts. 相似文献
60.
Neuropsychological investigation of the development of the mnesic function in mental retardation has primarily focused on evaluating short-term memory (STM). Studies have often documented a reduced verbal short-term memory span in individuals with mental retardation and with Down syndrome in particular, compared to groups of mental age-matched controls. However, recent evidence suggests that verbal short-term memory is not equally impaired in all individuals with mental retardation. Findings in children with Williams syndrome are particularly relevant in this regard. Also, data concerning STM for visual information suggest that visual-object and visual-spatial working memory may be differently compromised in people with mental retardation. In particular, individuals with Williams syndrome exhibit specific difficulties in visual-spatial but not in visual-object working memory tasks compared to typically-developing children matched for mental age. Instead, people with Down syndrome show reduced performance in both visual-spatial and visual-object tests. Taken together, these results reinforce the view that intellectual disability is not a unitary condition characterized by homogeneous slowness of cognitive development but a variety of conditions in which some cognitive functions may be more disrupted than others. The finding that the working memory deficit in individuals with Williams and Down syndrome may be qualitatively differentiated also supports the hypothesis that it is not simply a manifestation of general cognitive impairment but, rather, the expression of a specific deficit of a discrete cognitive ability. 相似文献