Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats

Spermidine (SPD) is an endogenous polyamine that modulates N-methyl-D-aspartate (NMDA) receptor function, and has been reported to facilitate memory formation. In the current study we determined whether or not the PKA/CREB signaling pathway is involved in SPD-induced facilitation of memory of inhibitory avoidance task in adult rats. The post-training administration of the cAMP-dependent protein kinase (PKA) inhibitor, N-[2-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide [H-89, 0.5 ρmol intrahippocampal (ih)] or the antagonist of the NMDA receptor polyamine-binding site (arcaine, 0.02 nmol ih) with SPD (0.2 nmol ih) prevented memory improvement induced by SPD. Intrahippocampal administration of SPD (0.2 nmol) facilitated PKA and cAMP response element-binding protein (CREB) phosphorylation in the hippocampus 180 min, but not 30 min, after administration, and increased translocation of the catalytic subunit of PKA into the nucleus. Arcaine (0.02 nmol) and H-89 (0.5 ρmol) prevented the stimulatory effect of SPD on PKA and CREB phosphorylation. These results suggest that memory enhancement induced by the ih administration of SPD involves the PKA/CREB pathways in rats.     

Prevention of delinquency: Current status and issues

In the present review, we summarize the extant literature in the field of delinquency prevention. We do not provide a recounting of whether specific programs have or have not been effective but, rather, attempt to judge the overall utility of programs to prevent delinquency in its various forms and among various definable groups. Specifically, we organize our review of programs according to the characteristics of the targeted population, differentiating programs for universal, selected, or indicated populations. Within each population type, we further distinguish programs according to designated intervention context, relying on a biopsychosocial model that specifies four levels of influence on risk for delinquency: individual, close interpersonal relationships, proximal social settings, and societal macrosystems. At each level, we identify a number of effective intervention strategies and highlight those that are based on relevant risk factor research. As we note, the effectiveness of some approaches depends on the specific population, although, in general, multicomponent, multilevel programs appear to have the most substantial effects.     

Promoting fluency of performance during morning dressing by two persons with multiple disabilities

This study investigated the possibility of promoting fluency of performance, i.e., a performance independent of caregiver's guidance and without serious interruptions, during morning dressing in two adults with multiple disabilities. The intervention program relied on the use of assistive technology including optic and pressure sensors to monitor the participants' task responding and tape players to present preferred stimuli in relation to such responding, as well as messages of encouragement. Analysis showed that the intervention program was effective with both participants. In fact, they became capable of performing the dressing sequence with only occasional guidance from research assistants, and the time they required for dressing dropped significantly from baseline levels. Implications of the results are discussed.     

LIBRE model: Engagement styles in counseling

Engagement is essential for the processing of information. It is presented here as 2 points along a continuum: initial attention (primary self‐presentation) and sustained attention (continued self‐regulation). The LIBRE (Listen, Identify, Brainstorm, Reality Test, Encourage) Stick Figure Tool (N. S. Guerra, 2003) provides a graphic organizer for LIBRE problem solving and is instrumental in the assessment of both initial and sustained engagement tendencies. A vignette is presented to illustrate the application of the model. Implications for the model are then discussed in relation to client engagement style in an employment counseling setting.     

Collective Narcissism Predicts Hypersensitivity to In‐group Insult and Direct and Indirect Retaliatory Intergroup Hostility

Results of five studies (N = 1596) linked collective narcissism—a belief in in‐group exaggerated greatness contingent on external validation—to direct and indirect, retaliatory hostility in response to situations that collective narcissists perceived as insulting to the in‐group but which fell well beyond the definition of an insult. In Turkey, collective narcissists responded with schadenfreude to the European economic crisis after feeling humiliated by the Turkish wait to be admitted to the European Union (Study 1). In Portugal, they supported hostile actions towards Germans and rejoiced in the German economic crisis after perceiving Germany's position in the European Union as more important than the position of Portugal (Study 2). In Poland, they supported hostile actions towards the makers of a movie they found offensive to Poland (Studies 3 and 5) and responded with direct and indirect hostility towards a celebrity whose jokes about the Polish government they found offensive (Study 4). Comparisons with self‐positivity and in‐group positivity indices and predictors of intergroup hostility indicated that collective narcissism is the only systematic predictor of hypersensitivity to in‐group insult followed by direct and indirect, retaliatory intergroup hostility. Copyright © 2016 European Association of Personality Psychology     

Parenting a Child with Learning Disabilities: Mothers’ Self-Forgiveness,Well-Being,and Parental Behaviors

Journal of Child and Family Studies - Parenting a child with learning disabilities (LDs) can not only be a fulfilling experience, but also a challenging one which can increase parenting stress as...     

Group status drives majority and minority integration preferences

This research examined preferences for national- and campus-level assimilative and pluralistic policies among Black and White students under different contexts, as majority- and minority-group members. We targeted attitudes at two universities, one where 85% of the student body is White, and another where 76% of students are Black. The results revealed that when a group constituted the majority, its members generally preferred assimilationist policies, and when a group constituted the minority, its members generally preferred pluralistic policies. The results support a functional perspective: Both majority and minority groups seek to protect and enhance their collective identities.     

Honor Scale: evidence on construct validity

Honor is an important construct, mainly emphasized in collectivist cultures, such as Brazil. However, there is a lack of studies regarding honor in this cultural context. Therefore, the current research aims at proposing a short version of the Honor Scale (HS‐16) to the Brazilian context. Construct validity (i.e., factorial, convergent, and discriminant validity, as well as internal consistency and composite reliability) is reported in Studies 1 (n = 220) and 2 (n = 222), with participants from general population. In both studies, participants answered the Honor Scale and demographic questions. The authors find the HS‐16 to be a reliable and valid scale, thereby enabling its use in quantitative studies regarding the correlates of honor concerns.