Increased regional cerebral glucose metabolism and semantic memory performance in Alzheimer's disease: A pilot double blind transdermal nicotine positron emission tomography study

Nicotinic receptor dysfunction and impaired semantic memory occur early in Alzheimer's disease patients (AD). Previous research implied that nicotine's ability to enhance alertness, arousal, and cognition in a number of nonclinical populations was a function of its ability to stimulate CNS nicotinic cholinergic receptors. In this study it was hypothesized that transdermal administration of nicotine would increase both regional cerebral glucose metabolism (rCMRglc) and semantic memory (as assessed by verbal fluency). Two mild AD and two elderly controls underwent positron emission tomography scanning during a double blind nicotinic agonist verbal fluency challenge procedure. rCMRglc increases occurred in both AD patients, but not controls. In the two AD patients, verbal fluency scores increased by an average of 17%. One elderly control's verbal fluency increased, and the other decreased. These findings suggest that nicotine's effect on metabolism and verbal fluency is due to its ability to stimulate the cholinergic system.     

Role of Informal Integration in Career Advancement: Investigations in Plural and Multicultural Organizations and Implications for Diversity Valuation

The major question which this research examinedis whether informal integration is likely to result incareer advancement and perceived resources within twodifferent organizational contexts (plural and multicultural). Specifically, we examinedinteractions of race, gender, and organization type onthe above two outcome variables. In pluralorganizations, employees are expected to assimilate intothe dominant culture, while in multicultural organizations,cultural change for the individual and the organizationis reciprocal. Hypotheses were tested with a combinedsample of 101 men, 35 women, 29 persons of color, and 107 whites. Results indicated that,congruent with predictions, greater social integrationoccurred in an organizational context in which valuingdifferences was a priority. Further, the influence of informal integration on career advancement wasstill important even after controlling for suchvariables as age, organizational tenure, education, andhierarchical level within the organization. Implications of these findings for valuing diversity arediscussed.     

Myrtle McGraw''s Unrecognized Conceptual Contribution to Developmental Psychology

In the late nineteenth century and through much of the twentieth century, the notion of the early developmental autonomy of motor behavior pervaded behavioral embryology and the developmental psychology of infant behavior. In the midst of this predeterministic climate of opinion concerning motor development, Myrtle McGraw briefly and tentatively broached the probabilistic epigenetic notion of a bidirectional or reciprocal relationship between structural maturation and function, whereby structural maturation of the nervous system is influenced by functional activity as well as the other way around. Myrtle McGraw thus anticipated our current understanding of the role of experience in the cortical and motor maturation of infants in the first year of postnatal life. It is all the more remarkable that she made this contribution when the theoretical climate of opinion was epitomized by predeterministic epigenetic thinking. In the same vein, McGraw's second unrecognized contribution is her clear formulation of a suitably flexible critical period concept in 1935, one that is consonant with our current understanding.     

The probabilistic import of illatives

It is not only overtly probabilistic illatives like makes it certain that but also apparently non-probabilistic ones like therefore that have probabilistic import. Illatives like therefore convey the meaning that the premise confers on the conclusion a probability not only greater than 0 but also greater than 1/2. But because they do not say whether that probability is equal to or less than 1, these illatives are appropriately called neutral.     

Posttraumatic recovery of traumatized newborns: effects on neuromotor and cognitive development during their first 6 months

Recovery after perinatal cerebral traumatism was studied in a group of 20 traumatized infants. The effects on the sequence of development during the next 6 months were observed for both motor and cognitive development and were compared with a control group of 20 normal babies. Results showed a significant delay for the abnormal group and a different recovery pattern between these two aspects of development. Motor development reached a normal level at 4 months, whereas cognitive development was still impaired at 6 months. These results were discussed in terms of possibly longer effects of perinatal traumatism on higher cortical functions than on motor functions.     

External locus of control in children of alcoholics.

The relationship of type of home of origin [alcoholic parent(s) versus nonalcoholic parent(s)] to locus of control was assessed. Perceived level of parental alcohol abuse (MAST score) did not predict 121 students' locus of control. However, external orientation was significantly and positively correlated with having a parent who drank heavily and scores on the Beck Depression Inventory and significantly and negatively correlated with the Rosenberg Self-esteem Inventory and the Possible Self Questionnaire.     

Memory of imagined actions: Imagining oneself or another person

Summary In two experiments, three modes of action encoding were compared: overt enactment, self-imagination, and imagination of another person performing the actions. Overt enactment and imagining self-performance of an action are mainly assumed to involve motor-kinesthetic representations, whereas imagining another person is thought to place more demands on the visual representational system. Previous paired-associate learning data on memory of action verbs showed that motor-kinesthetic imagery hinders pair integration, but that pair integration is facilitated by visual imagery. The comparison of free and cued recall of actions learned from lists of concrete nouns supports the assumption that the representational properties of overt enactment and self-imagination differ from those involved in the imagining of another person.     

Pair-relational encoding of performed nouns and verbs

Summary Subjects had to learn lists of noun pairs and verb pairs. They were informed in advance about the test types and were tested for free recall (FR) and cued recall (CR). Three classes of encoding instructions were used: standard learning instructions, item-specific enactment instructions (to perform the denoted action of the verb or a typical action for the noun, and to do the same plus finding separate goals for the two elements of each pair), and enactment instructions that were completed by explicit instructions to integrate the word pairs (find a common goal, and find a common goal plus rating your success). There was no effect of encoding instructions on FR of nouns. There was a better FR under all enactment instructions than under standard instructions for verbs. CR decreased after item-specific enactment instructions, in contrast with standard learning instructions, but more for nouns than for verbs. CR increased after the instructions to integrate the pairs, in contrast with item-specific enactment instructions, but more for nouns than for verbs. It was concluded that enactment provides excellent item-specific information that can hardly be enhanced further, and that the item-specific information provided by concrete nouns is fundamentally good and is difficult to enhance by enactment. It is further assumed that enactment not only provides excellent item-specific information, but also hinders pair integration. Therefore, CR decreases after enactment. This decrease can only be overcome when subjects actively try to integrate the word pairs.     

Winning or Losing Against an Opposite-Sex Peer on a Gender-Based Competitive Task

Two studies with heterosexual female and malecollege students explored the effects on mood and bodyimage resulting from a negative versus a positiveoutcome in a competitive interaction. In study 1,participants either succeeded or failed in comparison to anopposite-sex confederate on a gender-neutral task ofanagram solution. Study 2 added the dimension of thegender stereotypicality of the task by creatingempirically derived feminine (beauty aid knowledge) andmasculine (tool construction knowledge) conditions. Theresults indicated that women's anger significantlyincreased following the masculine task, regardless of the outcome. A marginally significantthree-way interaction resulted for the depressionmeasure: Females who won at the masculine task hadhigher levels of depression than males in thiscondition, and higher levels than both males and females inthe masculine-lose condition. In contrast, males who“won” on the feminine task had higher levelsof depression than females in this condition, and higher levels than both males and females who lost onthe feminine task. Discussion centers on the potentialusefulness of the gender-stereotypicality measure forfuture research and the need for followup work to replicate the current findings.     

Analysis of factor structure in a dream inventory

Intercorrelations of responses to the KJP dream inventory, initially a checklist of dream elements, were factor analyzed from a database from 65 graduate majors in psychology. Six factors were identified within the checklist: repetitive traumatic dreaming, reoccurring pleasantness, openness or depth, discontentedness, dissociative avoidance, and uninhibitedness. Scoring criteria were developed for each subscale.