Both exposure to a novel context and associative learning induce an upregulation of AKAP150 protein in mouse hippocampus

A-kinase anchoring protein 150 (AKAP150) is a multi-enzyme signaling complex that coordinates the action of PKA, PKC, and PP2B at neuronal membranes and synapses. We measured levels of AKAP150 protein in the hippocampus 6h after training mice in a contextual fear conditioning paradigm. In contextual fear conditioning mice learn to associate a context with a footshock presentation. Mice were divided in four experimental groups with different training protocols: naive, no footshock exposure, immediate footshock exposure, and footshock 3min after exposure to the context. We found that AKAP150 protein levels were increased upon exposing mice to the novel context independent of the training protocol. However, when the animals were habituated to the experimental context, only mice that learned to associate the context with the footshock showed an upregulation of AKAP150. We suggest that upregulated levels of AKAP150 contribute to processing the exposure to a novel context and associative learning.     

Differences between children and adults in the recognition of enjoyment smiles

The authors investigated the differences between 8-year-olds (n=80) and adults (n=80) in recognition of felt versus faked enjoyment smiles by using a newly developed picture set that is based on the Facial Action Coding System. The authors tested the effect of different facial action units (AUs) on judgments of smile authenticity. Multiple regression showed that children base their judgment on AU intensity of both mouth and eyes, with relatively little distinction between the Duchenne marker (AU6 or "cheek raiser") and a different voluntary muscle that has a similar effect on eye aperture (AU7 or "lid tightener"). Adults discriminate well between AU6 and AU7 and seem to use eye-mouth discrepancy as a major cue of authenticity. Bared-teeth smiles (involving AU25) are particularly salient to both groups. The authors propose and discuss an initial developmental model of the smile recognition process.     

Failure to replicate the 'work ethic" effect in pigeons

We report six unsuccessful attempts to replicate the "work ethic" phenomenon reported by Clement, Feltus, Kaiser, and Zentall (2000). In Experiments 1-5, pigeons learned two simultaneous discriminations in which the S+ and S- stimuli were obtained by pecking an initial stimulus once or multiple (20 or 40) times. Subsequent preference tests between the S+ stimuli and between the S- stimuli mostly revealed indifference, on average, between the S+ from the multiple-peck (high-effort) trials and the S+ from the one-peck (low-effort) trials, and likewise between the two respective Sstimuli. Using a slightly different procedure that permitted assessment of the relative aversiveness of low versus high effort, Experiment 6 again revealed a pattern of indifference despite showing that pigeons took considerably longer to begin pecking on high- than on low-effort trials. Our findings call into question the reliability of the original findings and the sufficiency of the hypothesized within-trial contrast mechanism to produce them.     

Common and distinct factors in decision making under ambiguity and risk: A psychometric study of individual differences

The relation between decision making under ambiguity and risky decision making was examined. In Studies 1 and 2, choices under ambiguity were measured for a large sample receiving an Ellsberg-type Ambiguity-Probability Tradeoff Task. Participants with extreme scores were recruited for Part 2 of each study which consisted of a risky decision making task (Study 1) or a series of decisions under ambiguity in “real life” scenarios (Study 2). Despite a time gap of up to 2 months, individual differences in scores on Part 1 predicted scores on Part 2. In Study 3 participants received in a single session several risky decision making tasks, several measures of decision making under ambiguity, and several personality scales related to uncertainty and decision making style. Taken together, the findings support the existence of a stable dispositional trait to reduce uncertainty in decision making but also task-specific differences related to gains and losses.     

Investigation of age and gender effects on positive orientation in Italian twins

We investigated age and gender effects on “Positive Orientation” (POS)—an individual's tendency to view life with a positive outlook—using a genetically informed design. Study subjects were 1016 twins aged 22–75 from the Italian twin registry. We assessed POS by the recently developed P‐scale. First, we used confirmatory factor analysis to investigate scale's measurement invariance by age and gender. Then, we applied biometric modelling to estimate genetic and environmental components of POS score. Overall, we found a satisfactory degree of measurement invariance by both age and gender. Results from these analyses further indicated an increasing mean level of POS across the lifespan. Additive genetic and unshared environmental factors explained respectively 58% and 42% of variance in POS score, with no significant gender differences; furthermore, the pattern of change of gene‐environment architecture of POS over time was consistent with a greater plasticity of personality at older ages.     

Food Cravings Questionnaire–Trait (FCQ–T) Discriminates Between Obese and Overweight Patients With and Without Binge Eating Tendencies: The Italian Version of the FCQ–T

Food craving (FC) might play an important role in the course of eating disorders and obesity. The question of its measurement has particular importance in relation to the dramatic growth in obesity rates and its relevance for public health. The aim of this study was to investigate the psychometric properties of the Italian version of the Food Cravings Questionnaire–Trait (FCQ–T) in overweight and obese patients who were attending weight loss programs, and its efficiency in discriminating patients with binge eating. Participants were 497 (411 women, 86 men) overweight and obese patients in treatment with low-energy diet therapy. We used structural equation modeling to compare 3 factor models tested in previous studies (a 6-factor model, an 8-factor model, and a 9-factor model), which indicated that the 9-factor model has a better fit over the competing models. The FCQ–T had good internal consistency (Cronbach's α of.96 for the total score, and between.76 and.92 for subfactors), and was able to discriminate patients with clinical-level binge eating from those with probable and without binge eating with an efficiency of.74 (sensitivity =.64, specificity =.78). FCQ–T scores were sensitive to changes associated with treatment only for patients who started dietary restriction between the baseline and the follow-up assessment, but not for patients who were already observing dietary restrictions at the time of the baseline assessment. These results suggest that the FCQ–T could be a potentially useful measure for the screening of binge eating problems in overweight and obese patients while in treatment.     

Revisiting the Psychometric Properties of the Levenson Self-Report Psychopathy Scale

A number of studies have addressed the dimensionality and the measurement invariance of the Levenson Self-Report Psychopathy scale (LSRP; Levenson, Kiehl, & Fitzpatrick, 1995). However, previous investigations exclusively relied on North American samples and mainly on statistical methods that assume data as normally and continuously distributed. The aim of this study was to further investigate dimensionality and differential item functioning for gender in the 26-item LSRP scale in a Brazilian population-based sample using analytical methods adequate for ordered categorical variables. Findings revealed strong evidence for a 2-factor model, similar to the original factor structure of the instrument. Only 3 items presented negligible differential functioning for gender. We address the implications of these results, and stress the need for expanding research on the measurement and structural invariance of the LSRP scale by means of cross-cultural investigations.     

Patients are not fully human: a nurse's coping response to stress

In this article, dehumanization of patients was studied as a strategy used by nurses to cope with stress. Affective organizational commitment (AOC) and affective commitment to patients (ACP) were tested as moderators. We also explored how nurses' humanity attributions to their in‐group relate to stress symptoms. Participants were nurses working in different wards of an Italian urban hospital. Findings showed that perceiving patients as not fully human was related to lower levels of stress symptoms for nurses with high AOC and ACP, but not for nurses with low AOC and ACP. Moreover, for highly committed nurses, the attribution of uniquely human traits to the in‐group was associated with increased stress symptoms. Implications of findings for the relationship between nurses and patients are discussed.     

Development and natural kinds

While philosophers tend to consider a single type of causal history, biologists distinguish between two kinds of causal history: evolutionary history and developmental history. This essay studies the peculiarity of development as a criterion for the individuation of biological traits and its relation to form, function, and evolution. By focusing on examples involving serial homologies and genetic reprogramming, we argue that morphology (form) and function, even when supplemented with evolutionary history, are sometimes insufficient to individuate traits. Developmental mechanisms bring in a novel aspect to the business of classification—identity of process-type—according to which entities are type-identical across individuals and natural kinds in virtue of the fact that they form and develop through similar processes. These considerations bear important metaphysical implications and have potential applications in several areas of philosophy.