Delineation of a spatial working memory profile using a non-verbal eye-tracking paradigm in young children with autism and Williams syndrome

Working memory deficits profoundly inhibit children’s ability to learn. While deficits have been identified in disorders such as autism spectrum disorder (ASD) and Williams syndrome (WS), findings are equivocal, and very little is known about the nature of these deficits early in development. A major barrier to advances in this area is the availability of tasks suitable for young children with neurodevelopmental disorders who experience difficulties with following verbal instructions or who are distressed by formal testing demands. To address these issues, a novel eye-tracking paradigm was designed based on an adaptation of the classic A not B paradigm in order to examine the early foundations of spatial working memory capabilities in 26 developmentally delayed preschool children with ASD, 18 age- and IQ-matched children with WS, and 19 age-matched typically-developing (TD) children. The results revealed evidence that foundational spatial working memory performance in ASD and WS was comparable with that of TD children. Performance was associated with intellectual ability in the ASD and TD groups, but not in the WS group. Performance was not associated with adaptive behavior in any group. These findings are discussed in the context of previous research that has been largely limited to older and substantially less developmentally delayed children with these neurodevelopmental disorders.     

A Characterization of von Neumann Games in Terms of Memory

An information completion of an extensive game is obtained by extending the information partition of every player from the set of her decision nodes to the set of all nodes. The extended partition satisfies Memory of Past Knowledge (MPK) if at any node a player remembers what she knew at earlier nodes. It is shown that MPK can be satisfied in a game if and only if the game is von Neumann (vN) and satisfies memory at decision nodes (the restriction of MPK to a player's own decision nodes). A game is vN if any two decision nodes that belong to the same information set of a player have the same number of predecessors. By providing an axiom for MPK we also obtain a syntactic characterization of the said class of vN games.     

Behavioral effects of testosterone in relation to social rank in the male rabbit

The role of gonadal androgens in favoring the adaptation to environmental pressure, including social organization, is well known. In the rabbit, testosterone administration increases marking behavior, and its level can be affected by agonistic interaction. In this experiment, we studied the effect of subcutaneous administration of testosterone propionate (TP) (3 mg/d for 6 days) in male rabbits belonging to the same social group (6 groups of 4 animals). In 2 additional groups (4 animals each), males were injected with almond oil. The animals were observed for 6 days in seminatural conditions, then treated with TP (or oil) and observed for another 6 days. The dominant/subordinate frequency ratio of behavioral patterns was used to rank the animals. The testosterone plasma concentration was correlated with agonistic behavior after the first period of social interaction. A significant increase of marking, digging, and defensive activity was observed after TP administration in all animals independent of rank, whereas this increase was not present in animals treated with oil. Agonistic and interactive behaviors increased significantly after TP treatment only in the first‐ranking animals. This indicates the influence of social rank in the modification of behaviors involving interactions among subjects Aggr. Behav. 29:269–278, 2003. © 2003 Wiley‐Liss, Inc.     

Evidence for a workspace model of working memory from semantic implicit processing in neglect

Three experiments tested the hypothesis that activation of semantic memory from perceptual input does not require initial retention of the perceptual material in working memory as assumed by a widely held view of information processing. In Expt 1, two brain-damaged patients with left-sided unilateral spatial neglect were tested. They were asked to listen to and read a series of familiar (British) and unfamiliar (foreign) proverbs and to choose which proverb was the best match to a depicted figure shown with the target object(s) on the left (neglected side) of the patients' visual field. Expt 2 simulated the testing conditions for the neglect patients with healthy participants using subliminal presentation of one half of each picture. Using different materials, Expt 3 replicated the outcomes of Expts 1 and 2 with a third neglect patient and a new group of controls. In all three experiments, participants appeared to be unaware of target features; however they selected familiar, but not unfamiliar, target proverbs above chance. The results showing implicit processing of semantic material can be explained by a model in which working memory is a separate system that deals with activated contents of semantic memory, and in which there is direct activation of semantic memory from perception without intermediate stages of processing in working memory.     

Jews,Economic Metaphors,and the Healthy Body Politic: The Jewish Role in Christian Economic Narratives and the Birth of Modern Economics

Jewish History - The linguistic structure of the Western Christian discourse about economics as resembling and symbolizing the entire logic of earthly government and order was closely connected to...     

Imaging the future: Does a qualitative analysis add to the picture?

Various studies report that patients with dense amnesia experience difficulties in simulating future events. It is argued that this resembles an inability to remember past episodes in that both indicate a deficit in mental scene construction. Such findings, however, rely upon quantitative content-based analyses of participants' verbal reports. Here, samples of verbal reports produced by participants with hippocampal lesions are subjected to a qualitative, discourse analysis of how participants and researchers negotiated the status of these reports. This shows that failure in mental scene construction can be viewed as an interactional achievement rather than the mere reporting of mental events. A multidisciplinary perspective which combines qualitative analysis with other forms of analytic technique may explain subtle differences between participants with hippocampal lesions and control participants.