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461.
The goal of this study was to examine the effect of guided affective imagery therapy in an outpatient setting.At first, 140 patients were recruited.Unfortunately, there were many drop-outs at the beginning of the study as well as at later assessments.The data of 66 patients could be evaluated.The patients were assessed at the beginning of the therapy, after 25 sessions, at the end of the therapy and 18 month after the end of the therapy. Because of too many drop-outs, the originally planned waiting-control-design was realized only to some extent.The diagnoses of the patients consisted mainly of neurotic disorders,many of them with a dysthymia. Data were gathered by standardized questionnaires. There were marked effects of the therapies at the end of the treatments and also at the follow-up evaluation.Effect sizes were larger than 0.8 in somatic symptoms, mood, depression and life satisfaction.On the one hand, therefore, these therapies had been very effective. On the other hand, it became obvious during the course of the study, how difficult it is to conduct such a design with many therapists in a private practice and without financial support.  相似文献   
462.
The role of relatives' expressed emotion (EE) in mediating the efficacy of family interventions has been studied in randomized controlled trials (RCTs) involving people with schizophrenia and depression. Reanalysis of two RCTs (n=48) by Leff (1989) indicated that lowering relatives' EE and/or reducing social contact between the patient and family members accounted for the efficacy of the intervention for schizophrenia. However, this relationship has not been investigated previously with regard to depression, and this paper presents the results of a recent RCT which included measurement of EE and other possible mediating variables. In this study, amelioration of the critical attitude of the partner did not account for the superiority of couples therapy over antidepressant medication, since the same change occurred in the drug group. However, reducing the patient's exposure to the partner's hostility partially explained the efficacy of couples therapy. Further research on the process of change in families undergoing therapy is indicated to identify the variables that account for the efficacy of therapy.  相似文献   
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465.
Jacoby's white noise task and an explicit recognition task were used to investigate whether individuals with eating disorders demonstrate implicit memory bias and explicit memory bias, respectively, for information related to eating and body appearance. Included were 33 women with eating disorders (seven with anorexia nervosa and 26 with bulimia nervosa), 29 with nonclinical eating disorder-related concerns, and 36 healthy controls. Results showed partial support for implicit memory bias but no support for explicit memory bias. These findings suggest that eating disorders may be characterized by relative initial automatic bias for eating disorder-relevant information but not by bias at later stages of information processing. However, previous studies have demonstrated explicit memory bias in eating disorders, which is inconsistent with this interpretation. Future research is required to clarify the precise cognitive biases associated with eating disorders.  相似文献   
466.
We present two ERP studies on the processing of word order variations in Japanese, a language that is suited to shedding further light on the implications of word order freedom for neurocognitive approaches to sentence comprehension. Experiment 1 used auditory presentation and revealed that initial accusative objects elicit increased processing costs in comparison to initial subjects (in the form of a transient negativity) only when followed by a prosodic boundary. A similar effect was observed using visual presentation in Experiment 2, however only for accusative but not for dative objects. These results support a relational account of word order processing, in which the costs of comprehending an object-initial word order are determined by the linearization properties of the initial object in relation to the linearization properties of possible upcoming arguments. In the absence of a prosodic boundary, the possibility for subject omission in Japanese renders it likely that the initial accusative is the only argument in the clause. Hence, no upcoming arguments are expected and no linearization problem can arise. A prosodic boundary or visual segmentation, by contrast, indicate an object-before-subject word order, thereby leading to a mismatch between argument "prominence" (e.g. in terms of thematic roles) and linear order. This mismatch is alleviated when the initial object is highly prominent itself (e.g. in the case of a dative, which can bear the higher-ranking thematic role in a two argument relation). We argue that the processing mechanism at work here can be distinguished from more general aspects of "dependency processing" in object-initial sentences.  相似文献   
467.
Freud's early paper Psychical (or mental) treatment, first published in a family reference book for educated lay persons, was reproduced in the Gesammelte Werke with a stated publication date of 1905. This date was subsequently called into question owing to certain parts of the subject-matter (the use of hypnosis and suggestion in 'mental treatment'), and the contribution was erroneously assigned, for instance by James Strachey, to the year 1890. This error is corrected in the present paper. Furthermore, the existence of a second edition of this reference book, which contains an addition to Freud's text and appeared in 1918-19, has previously gone unnoticed. The first edition had been published in 1905-6. Freud's contribution must, however, have been written at an appreciably earlier date. The probable time of its genesis is discussed. Freud's new text is reproduced (in English translation) for the first time in an appendix to this paper.  相似文献   
468.
Previously, we found that in the lateral amygdala (LA) of the mouse, WIN55,212-2 decreases both glutamatergic and GABAergic synaptic transmission via activation of the cannabinoid receptor type 1 (CB1), yet produces an overall reduction of neuronal excitability. This suggests that the effects on excitatory transmission override those on inhibitory transmission. Here we show that CB1 activation by WIN55,212-2 and Delta(9)-THC inhibits long-term depression (LTD) of basal synaptic transmission in the LA, induced by low-frequency stimulation (LFS; 900 pulses/1 Hz). The CB1 agonist WIN55,212-2 blocked LTD via G(i/o) proteins, activation of inwardly rectifying K+ channels (K(ir)s), inhibition of the adenylate cyclase-protein kinase A (PKA) pathway, and PKA-dependent inhibition of voltage-gated N-type Ca2+ channels (N-type VGCCs). Interestingly, WIN55,212-2 effects on LTD were abolished in CB1 knock-out mice (CB1-KO), and in conditional mutants lacking CB1 expression only in GABAergic interneurons, but were still present in mutants lacking CB1 in principal forebrain neurons. LTD induction per se was unaffected by the CB1 antagonist SR141716A and was normally expressed in CB1-KO as well as in both conditional CB1 mutants. Our data demonstrate that activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the LA. These findings suggest that CB1 expressed on either glutamatergic or GABAergic neurons play a differential role in the control of synaptic transmission and plasticity.  相似文献   
469.
Spider phobia is a common and impairing mental disorder, yet little is known about what characteristics of spiders that spider phobic individuals find frightening. Using screening data from a clinical trial, we explored which characteristics that spider‐fearful individuals (n = 194) rated as having the greatest impact on fear, used factor analysis to group specific characteristics, and explored linear associations with self‐reported phobia symptoms. Second, a guided text‐mining approach was used to extract the most common words in free‐text responses to the question: “What is it about spiders that you find frightening?” Both analysis types suggested that movement‐related characteristics of spiders were the most important, followed by appearance characteristics. There were, however, no linear associations with degree of phobia symptoms. Our findings reveal the importance of targeting movement‐related fears in in‐vivo exposure therapy for spider phobia and using realistically animated spider stimuli in computer‐based experimental paradigms and clinical interventions such as Virtual Reality exposure therapy.  相似文献   
470.
When and how do social movements form to mobilize action across national boundaries? In the context of the 2015 movement to support Syrian refugees, we develop an integrative model of transnational social movement formation shaped by pre-existing world-views (social dominance orientation and right-wing authoritarianism) and social media exposure to iconic events, resulting in an emergent group consciousness (“we are”, “we believe”, “we feel”). Group consciousness is, in turn, the proximal predictor of solidarity with refugees. Participants were from six countries: Hungary (= 267), Romania (= 163), Germany (= 190), the United Kingdom (= 159), the United States (= 244) and Australia (= 344). Multi-group structural equation models confirmed that group consciousness, shaped by individual differences and exposure to events through social media, was the proximal predictor of solidarity. The subjective meaning of group consciousness varied across samples, reflecting national differences. Results support the importance of considering individual and national differences, and group processes in understanding emergent social movements.  相似文献   
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