Do women with fragile X syndrome have problems in switching attention: preliminary findings from ERP and fMRI

Fragile X syndrome (FXS) is a neurodevelopmental disorder that represents the most common known cause of developmental delay. Recent neuropsychological findings indicate that females with FXS present with a specific pattern of cognitive deficits and that these difficulties primarily involve skills requiring executive control. The present study is the first to examine the extent to which neural activity of females with FXS can be observed on a task that specifically taps two core deficits, namely switching and response inhibition. Brain activity was measured using both event-related electrical potentials (ERPs) and event-related functional MRI (fMRI) neuroimaging in separate studies using the same cognitive paradigm. Compared to controls, females with FXS were significantly slower and made more errors on trials that required an immediate response (Go) to stimulus onset but were comparable on trials that required a delayed response (Wait) to stimulus onset. At the brain level, several areas showed significantly greater activation for females with FXS compared with controls, including the cingulate cortex and left and right ventral prefrontal areas. In contrast, no areas were found to show significantly greater activation for controls compared with females with FXS.     

Working memory,reading ability and the effects of distance and typicality on anaphor resolution in children

We investigated the time course of anaphor resolution in children and whether this is modulated by individual differences in working memory and reading skill. The eye movements of 30 children (10–11 years) were monitored as they read short paragraphs in which (1) the semantic typicality of an antecedent and (2) its distance in relation to an anaphor were orthogonally manipulated. Children showed effects of distance and typicality on the anaphor itself and also on the word to the right of the anaphor, suggesting that anaphoric processing begins immediately but continues after the eyes have left the anaphor. Furthermore, children showed no evidence of resolving anaphors in the most difficult condition (distant atypical antecedent), suggesting that anaphoric processing that is demanding may not occur online in children of this age. Finally, working memory capacity and reading comprehension skill affect the magnitude and time course of typicality and distance effects during anaphoric processing.     

Love attitudes and relationship experience

The present study examined the association of love attitudes with the initiation, maintenance, and dissolution of relationships. Respondents completed the Love Attitudes Scale and a questionnaire designed to measure experiences at each stage of relationship development. Ludus was relevant to all stages of relationship development; ludic attitudes were associated with absence of concern for partner loyalty, short and uncommitted relationships, and positive feelings about relationship dissolution. Pragma was associated primarily with relationship initiation (i.e., selection of an appropriate partner). Agape and Mania were most apparent during maintenance, as evidenced by relationships with indicators of involvement and loyalty. Agape, Mania, and Eros related to negative emotions at the point of relationship dissolution.     

Donating to disaster victims: Responses to natural and humanly caused events

The effect of the cause of a disaster, i.e. whether it was perceived to be caused by human or natural factors, on willingness to donate money to disaster victims was examined. In Study 1 (N = 76), the cause of a fictitious disaster was experimentally varied. In Study 2 (N = 219), participants were asked about their views regarding donations to two real‐life disasters, one of which was perceived to be naturally caused while the other one was perceived to be caused by humans. In Study 3 (N = 115), the cause of a fictitious disaster was experimentally varied, but this time measures of the proposed psychological mediators of the effect on donations were included, namely perceived victim blame and the extent to which victims were thought to make an effort to help themselves. A measure of real donation behaviour was also added. In Study 4 (N = 196), the proposed psychological mediators were manipulated directly, and the effect of this on donations was monitored. Across all studies, more donations were elicited by naturally caused rather than humanly caused disasters. This difference was driven by a perception that the victims of natural disasters are to be blamed less for their plight, and that they make more of an effort to help themselves. Implications for theory and practice are discussed. Copyright © 2010 John Wiley & Sons, Ltd.     

The survey of personal beliefs: comparison of south african, mexican and american samples

In order to investigate the cross-cultural reliability and independence of subscales of the Survey of Personal Beliefs (SPB) data from 751 undergraduate Psychology students (189 White South African students, 114 Black South African students, 262 Mexican students and 186 American students) were compared. Coefficient alphas for the subscales in all samples were low, ranging from .33 to .76. However, alphas for the total scale across all subgroups were high. A comparison of the rank ordering of alpha coefficients for subscales in the different samples partially supported the cross-cultural reliability of the SPB for White South African and Mexican students, and for Black South African and American students. The similarities across samples regarding intercorrelations and shared variance between subscales also provided some evidence for the possible cross-cultural independence of subscales of the SPB. Comparison of total and mean subscale scores showed no significant differences between males and females within samples. However, a significant effect for culture, with significant between-subject effects for all the subscales as well as for the total score, was found. This may be indicative of real differences in irrational belief styles between the groups or may be a result of the insufficient cross-cultural reliability of the SPB.     

Development and Evaluation of a Telephone Communication Protocol for the Delivery of Personalized Melanoma Genomic Risk to the General Population

Communicating personalized genomic risk results for common diseases to the general population as a form of tailored prevention is novel and may require alternative genetic counseling service delivery models. We describe the development and evaluation of a communication protocol for disclosing melanoma genomic risk information to the asymptomatic general population and assess participants’ satisfaction and acceptability. Participants (n?=?117) were aged 22–69 years, living in New South Wales, Australia and unselected for family history. They provided a saliva sample and had genomic testing for melanoma for low to moderate penetrant melanoma susceptibility variants in 21 genes. Participants could choose to receive their results from a genetic counselor via telephone, followed by a mailed booklet or to receive their risk result via mailed booklet only with a follow-up call for those at high risk. A follow-up questionnaire was completed by 85% of participants 3-months later. Most participants (80%) elected to receive their result via telephone. Participants were highly satisfied with the delivery of results (mean 3.4 out of 4, standard deviation 0.5), and this did not differ by delivery mode, risk category, age or sex. On follow-up, 75% accurately recalled their risk category, 6% indicated a preference for a different delivery mode, either electronic or face-to-face. The process of disclosing genomic risk results to the general population over the telephone with accompanying written material was feasible and acceptable, and may be useful for communicating polygenic risk for common diseases in the context of increasing demands for genomic testing.     

Resolving conflicting social categories: the role of age-related executive ability

We investigated the effect of age-related decline in executive ability on the application of emergent features to incongruent social category conjunctions (e.g., male midwife). When forming an impression of an incongruent conjunction, older adults used more emergent attributes (attributes associated exclusively with the category conjunction and not the constituents), relative to younger adults. Moreover, this relationship was mediated by a reduction in inhibitory ability (measured using a Stroop task) and processing speed (measured using a Digit Symbol Substitution Test, DSST). These findings are consistent with the notion that executive ability is pivotal in understanding social functioning in older adults. We discuss the implications of these findings for the continuing development of models outlining the processes and stages involved in perceiving social category conjunctions.