A Psychoneuroimmunologic Perspective on AIDS Research: Questions,Preliminary Findings,and Suggestions1

Starting with the premise that research questions emanating from the fields of psychoneuroimmunology and behavioral medicine may provide critical information for understanding and treating acquired immune deficiency syndrome (AIDS), we provide brief backgrounds on psychoneuroimmunology and on AIDS. Previously, Solomon had generated 25 hypotheses based on the thesis that the immune and central nervous systems are intimately linked. Eight hypotheses from his list are presented as particularly relevant to AIDS. From these hypotheses, we derived a set of 12 new questions to be addressed in research on AIDS. Evidence and illustrations from studies in the literature, from our own research on psychoimmunologic relationships and psychosocial factors related to outcome, and from clinical examples is discussed for each question. Finally, suggestions are offered to address some of the problems in conducting psychoneurologic research.     

Process parallels in related groups

The theoretical basis for the repetition of themes in related groups is addressed by describing similar processes in four systems: inpatient psychiatric ward, inpatient psychotherapy group, supervisory group, and group psychotherapy division. The principles of general system theory help explain process parallels in allied groups and illuminate group process.     

Pavlov as a psychologist

American psychologists are informed on Pavlov’s work on conditional reflexes but not on the full development of his theory of higher nervous activity. This article shows that Pavlov’s theory of higher nervous activity dealt with concepts that concerned contemporary psychologists. Pavlov used the conditioning of the salivary reflex for methodological purposes. Pavlov’s theory of higher nervous activity encompassed overt behavior, neural processes, and the conscious experience. The strong Darwinian element of Pavlov’s theory, with its stress on the higher organisms’ adaptation, is described. With regard to learning, Pavlov, at the end of his scholarly career, proposed that although all learning involves the formation of associations, the organism’s adaptation to the environment is established through conditioning, but the accumulation of knowledge is established by trial and error.     

PRIMARY ENCOPRESIS: EVALUATION AND TREATMENT

Cathartic and behavioral treatment procedures for eliminating diurnal and nocturnal primary encopresis were investigated using a multiple-baseline design across four children. The dependent and independent variables measured were appropriate bowel movements, soiling accidents, independent toiletings, and cathartic use. Over 177 reliability observations (home visits) were conducted. For two of the children, treatment with cathartics and child-time remedied their soiling accidents and increased their independent toiletings in 8 to 11 weeks. While the cathartics and child-time increased the rate of appropriate bowel movements, they did not eliminate the soiling accidents with the other two children. Independent toiletings for these two children were achieved after 32 to 39 weeks of treatment when punishment procedures (positive practice, time-out, and hourly toilet sits) were incorporated and the suppositories were faded systematically.     

Personal identity and brain death: a critical response

The authors contend that there are logical inconsistencies in a theory put forth by Michael Green and Daniel Wikler ("Brain death and personal identity," Philosophy and Public Affairs 1980 Winter; 9(2): 105-133) to justify the brain death concept of death. Green and Wikler had asserted that individuals cease to exist and are dead when the criteria for continuity in their personal identity are not met. Having argued that the theory of personal identity is misguided, Agich and Jones suggest that further research into the ontological foundation of brain death concepts should begin, not by rejecting medical or moral considerations, but by carefully defining the main competing concepts of brain death as brain stem death, cerebral death, death of the brain as a whole, and whole brain death, and then by relating these concepts to the ontological conditions for being a live individual or person.     

The effect of subject's gender on judgments of similarity and choice of a comparison other

This study examined the implications for social comparison theory of the proposition that women have lower self-confidence than men when there is a socially defined standard of performance. To this end, it was hypothesized that women would judge themselves to be similar to a lower ranked person, whereas men would judge themselves to be similar to a higher ranked person. Furthermore, it was hypothesized that women would choose to see a score lower than their own, whereas men would choose to see a score higher than their own. The results on the measure of similarity indicated that men did judge themselves to be similar to a higher ranked person, whereas women showed no consistent preferences in their judgments of similarity. The results on the choice of a comparison other were not as clear-cut.     

Duration of negative practice and the reduction of leg pounding of a traumatically brain-injured adult

This study evaluated the relative efficacy of long (1 minute) and short (15 seconds) durations of negative practice for reducing self-stimulatory leg pounding of a traumatically brain-injured adult. In individual social skill training classes, long negative practice and short negative practice were administered concurrently in an alternating treatments design. Generalization of treatment effects outside of training sessions was assessed during the client's lunch period. The results revealed that both durations of negative practice were equally effective in reducing leg pounding during training sessions. However, the effects of training did not generalize to settings in which the practice contingency was not enforced. Pounding was more frequent and negative practice somewhat less effective during periods of high social stimulation.     

Selective attention and rehearsal in the auditory short-term memory task performance of poor and normal readers

The performance of poor and normal sixth-grade readers was compared on an auditory short-term memory task in two studies. In the first study, the effects of distraction, list length, and speed of stimulus presentation were investigated to test the hypothesis that the performance of the poor readers is affected by deficits in selective attention. Group differences in performance, however, were obtained for both distraction and no-distraction conditions. The second experiment examined the hypothesis that group differences may reflect differences in the use of rehearsal. In the second experiment, half the reading-disabled children and half the controls were provided with rehearsal training prior to completing the same short-term memory task a second time. Rehearsal training resulted in improved performance relative to children who were not trained; however, there was no rehearsal training x reading group interaction. The poor readers continued to show deficits in performance relative to the performance of control children. The results of these two studies suggest that deficits observed for poor readers on short-term memory tasks may reflect processing difficulties in some area that precedes rehearsal and affects performance under both distraction and no-distraction conditions.The authors wish to express their thanks to the Sachem School District and Betty Gould, Nicholas Opinanate, and Guy Barber for their unlimited cooperation, and to John Neale for very helpful discussions of a number of issues in this paper.     

An individualized regression and clustering assessment of the social values of adults and children

Research investigating social values in interdependency situations has generally demonstrated age differences across the 5- to 10-year-old age range. However, the precise nature of these differences is unclear. Further, the differences in the social values of adults and children has not been addressed. The present study examined the social values of undergraduates and children using a measurement technique designed to allow an accurate inference of social values. Ninety-one 6- to 10-year-old children and 100 undergraduates rated the desirability of a set of outcomes which systematically varied with regard to the benefits to themselves and another person. Theoretically specified characteristics of the outcomes were then used to generate a regression equation predicting the desirability ratings separately for each individual. These regression equations were then clustered into groups of individuals who used decision rules characteristic of the major social values. The results indicate that the 8- to 10-year-old children, compared to the 6- to 7-year olds, more often expressed a social value involving equality and tended to less often express a social value involving superiority. Comparison of the social values expressed by the children and adults indicated that the adults more often expressed group-enhancement and individualism social values and less often expressed a social value involving superiority.