Operant methods for mouse psychoacoustics

Tone detection thresholds for a 10-kHz tone in NMRI mice were determined in psychoacoustic experiments using both a constant-stimuli procedure and a two-down/one-up adaptive-tracking procedure in the same subjects and applying identical threshold criteria (70.7% response probability). Constant-stimuli thresholds were on average 24 dB lower than adaptive-tracking thresholds, and there was a trend indicating that constant-stimuli thresholds were less variable than adaptive-tracking thresholds. Furthermore, in the constant-stimuli procedure the number of trials constituting the psychometric function could be reduced from 100 to 50 trials without a large loss of accuracy of threshold determination. In the constant-stimuli procedure, the threshold value was affected by the threshold criteria. The lowest and least variable constant-stimuli thresholds were obtained by applying signal detection theory and a criterion ofd′=1. Thus, the constant-stimuli procedure in combination with signal detection theory appears to be better suited than the adaptive-tracking procedure to determine auditory sensory thresholds.     

What catatonia can tell us about "top-down modulation": a neuropsychiatric hypothesis

Differential diagnosis of motor symptoms, for example, akinesia, may be difficult in clinical neuropsychiatry. Symptoms may be either of neurologic origin, for example, Parkinson's disease, or of psychiatric origin, for example, catatonia, leading to a so-called "conflict of paradigms." Despite their different origins, symptoms may appear more or less clinically similar. Possibility of dissociation between origin and clinical appearance may reflect functional brain organisation in general, and cortical-cortical/subcortical relations in particular. It is therefore hypothesized that similarities and differences between Parkinson's disease and catatonia may be accounted for by distinct kinds of modulation between cortico-cortical and cortico-subcortical relations. Catatonia can be characterized by concurrent motor, emotional, and behavioural symptoms. The different symptoms may be accounted for by dysfunction in orbitofrontal-prefrontal/parietal cortical connectivity reflecting "horizontal modulation" of cortico-cortical relation. Furthermore, alteration in "top-down modulation" reflecting "vertical modulation" of caudate and other basal ganglia by GABA-ergic mediated orbitofrontal cortical deficits may account for motor symptoms in catatonia. Parkinson's disease, in contrast, can be characterized by predominant motor symptoms. Motor symptoms may be accounted for by altered "bottom-up modulation" between dopaminergic mediated deficits in striatum and premotor/motor cortex. Clinical similarities between Parkinson's disease and catatonia with respect to akinesia may be related with involvement of the basal ganglia in both disorders. Clinical differences with respect to emotional and behavioural symptoms may be related with involvement of different cortical areas, that is, orbitofrontal/parietal and premotor/motor cortex implying distinct kinds of modulation--"vertical" and "horizontal" modulation, respectively.     

Elternschaft, Krebs und Kindersorgen

Background

The diagnosis of parental cancer may destabilize the whole family, parents and children as well. The Hamburg children of somatically ill parents (COSIP) intervention supports parental skills and adaptation of children to the situation. There is currently no evidence for criteria to determine which family members should be involved in the COSIP intervention, predominantly the parents (parent setting), the children (child setting) or both (family setting).

Aim of the study

Data from a multicentre study were analyzed with respect to the predominant intervention settings, the correlation between setting and aims of intervention as well as variables that predict the involvement of children in the intervention.

Material and methods

A total of 203 documented cases were analyzed. Different variables that had been documented by the therapists were included in a regression analysis model in order to identify predictive variables.

Results

In 142 cases the intervention was carried out in a specific intervention setting. In 57?% of the cases children were involved (32?% family setting and 25?% child setting). A systematic relationship between the reported intervention aims and the intervention setting was not detected. The most powerful predictor was the existence of emotional problems of children as reported by the child itself.

Conclusions

Decision-making on intervention settings should therefore take the assessment of emotional symptoms of children by the means of age-appropriate self-reporting tools into consideration. Further investigations are needed to reveal variables concerning needs, motivation and capabilities of the family members as well as institutional conditions.     

Terminal Feedback Outperforms Concurrent Visual,Auditory, and Haptic Feedback in Learning a Complex Rowing-Type Task

Augmented feedback, provided by coaches or displays, is a well-established strategy to accelerate motor learning. Frequent terminal feedback and concurrent feedback have been shown to be detrimental for simple motor task learning but supportive for complex motor task learning. However, conclusions on optimal feedback strategies have been mainly drawn from studies on artificial laboratory tasks with visual feedback only. Therefore, the authors compared the effectiveness of learning a complex, 3-dimensional rowing-type task with either concurrent visual, auditory, or haptic feedback to self-controlled terminal visual feedback. Results revealed that terminal visual feedback was most effective because it emphasized the internalization of task-relevant aspects. In contrast, concurrent feedback fostered the correction of task-irrelevant errors, which hindered learning. The concurrent visual and haptic feedback group performed much better during training with the feedback than in nonfeedback trials. Auditory feedback based on sonification of the movement error was not practical for training the 3-dimensional movement for most participants. Concurrent multimodal feedback in combination with terminal feedback may be most effective, especially if the feedback strategy is adapted to individual preferences and skill level.     

Tracking multiple objects across abrupt viewpoint changes

The reported experiment tested the effect of abrupt and unpredictable viewpoint changes on the attentional tracking of multiple objects in dynamic 3-D scenes. Observers tracked targets that moved independently among identically looking distractors on a rectangular floor plane. The tracking interval was 11 s. Abrupt rotational viewpoint changes of 10°, 20°, or 30° occurred after 8 s. Accuracy of tracking targets across a 10° viewpoint change was comparable to accuracy in a continuous control condition, whereas viewpoint changes of 20° and 30° impaired tracking performance considerably. This result suggests that tracking is mainly dependant on a low-level process whose performance is saved against small disturbances by the visual system's ability to compensate for small changes of retinocentric coordinates. Tracking across large viewpoint changes succeeds only if allocentric coordinates are remembered to relocate targets after displacements.     

The memorability of names and the divergent effects of prior experience

Pre-experimental familiarity can have paradoxical effects on episodic memory. Knowledge of the stimulus domain usually enhances memory, but word frequency—a presumed correlate of prior experience—is negatively related to recognition accuracy. The present study examined episodic recognition of names and its relation to two measures of pre-experimental knowledge, name frequency, and fame. Frequency was operationalised as the number of hits in a national telephone directory, and fame as hits on national mass media websites. Recognition accuracy was increased by fame, but diminished by frequency. Four experiments confirmed the findings, using yes/no recognition, ROC curves, and remember-know paradigms. Hit rates were consistently more strongly influenced by fame than by frequency, whereas the reverse was true for false alarm rates. These dissociations suggest that two different forms of semantic memory, specific and nonspecific knowledge, interact with episodic memory in separate ways.     

Extra‐powerful on the visuo‐perceptual space,but variable on the number space: Different effects of optokinetic stimulation in neglect patients

We studied the effects of optokinetic stimulation (OKS; leftward, rightward, control) on the visuo‐perceptual and number space, in the same sample, during line bisection and mental number interval bisection tasks. To this end, we tested six patients with right‐hemisphere damage and neglect, six patients with right‐hemisphere damage but without neglect, and six neurologically healthy participants. In patients with neglect, we found a strong effect of leftward OKS on line bisection, but not on mental number interval bisection. We suggest that OKS influences the number space only under specific conditions.     

INSIGHTFULNESS AND LATER INFANT ATTACHMENT IN CLINICALLY DEPRESSED AND NONCLINICAL MOTHERS

The aim of this pilot study was to investigate the relationship between maternal insightfulness and sensitivity and subsequent infant attachment security and disorganization in clinically depressed and nonclinical mother–infant groups. Nineteen depressed mothers with infants ages 3 to 11 months participated in this study. Twenty nonclinical mother–infant dyads were matched to the clinical sample according to infant sex and age. Maternal depression was assessed using the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (American Psychiatric Association, 1994), insightfulness using the Insightfulness Assessment (IA), and sensitivity using the Maternal Sensitivity Scales (M.D.S. Ainsworth, 1969). IA classifications and subscales were considered separately. Later infant attachment was assessed by the Strange Situation Procedure (M.D.S. Ainsworth, M.C. Blehar, E. Waters, & S. Wall, 1978). Depressed mothers tended to have less securely attached children than did nonclinical mothers. Within the clinical sample, the insightfulness categories correlated slightly moderately with attachment security, but were not related to attachment disorganization. Within the nonclinical sample, the IA categories were slightly moderately associated with attachment security and with disorganization. On IA subscales, relationship patterns differed in clinically depressed and nonclinical mother–infant dyads. These findings provide the first evidence of the predictive power of the IA categorization and subscales on subsequent infant attachment. They also may allow the development of different foci of intervention for enhancing insightful caregiving.     

Seelische Gesundheitsvorsorge f��r Kinder krebskranker Eltern

Children of cancer patients are increasingly being paid attention to as target group for family-based mental health prevention concepts in psychosocial oncology. Based on the long-term experiences with the concept Children of Somatically Ill Parents (COSIP) for child-centred medical family counselling, which was developed at the counselling service COSIP at the Hamburg University Medical Centre, a specialized manual was developed for the context of psychosocial care in oncology, which is currently being tested in a multi-center approach. In this article the theoretical framework and the practical steps of this manualized concept in caring for families with a parent having cancer are summarized. Characteristic elements are the flexible handling of the three system levels parents, family and child in the counselling setting as well as focussing on previously defined intervention goals which are expected to strengthen the coping resources in the family and the children. Perspectives for clinical practice and research are discussed.