Experiences of patients undergoing repeated intravitreal anti-vascular endothelial growth factor injections for neovascular age-related macular degeneration

Current therapy to slow disease progression in patients with neovascular age-related macular degeneration (AMD) entails regular intravitreal anti-vascular endothelial growth factor (VEGF) injections, often indefinitely. Little is known about the burden imposed on patients by this repetitive treatment schedule and how this can be best managed. The aim of this study was to explore the psychosocial impact of repeated intravitreal injections on patients with neovascular AMD. Forty patients (16 males, 24 females) with neovascular AMD undergoing anti-VEGF treatment were recruited using purposive sampling from a private ophthalmology practice and public hospital in Melbourne. Patients were surveyed using the Macular Disease Treatment Satisfaction Questionnaire (MacTSQ; Bradley, Health Psychology Research Unit, Surrey, England) and underwent semi-structured, one-on-one interviews. Interview topics were: treatment burden and satisfaction; tolerability; barriers to adherence; treatment motivation; and patient education. Interviews were audio recorded and thematic analysis performed using NVivo 10 (QSR International, Doncaster, Australia). Patients recognised the importance of treatment to preserve eyesight, yet experienced significant psychosocial and practical burden from the treatment schedule. Important issues included treatment-related anxiety, financial considerations and transport burden placed on relatives or carers. Many patients were restricted to sedentary activities post-injection owing to treatment side effects. Patients prioritised treatment, often sacrificing family, travel and social commitments owing to a fear of losing eyesight if treatment was not received. Whilst anti-VEGF injections represent the current mainstay of treatment for neovascular AMD, the ongoing treatment protocol imposes significant burden on patients. An understanding of the factors that contribute to the burden of treatment may help inform strategies to lessen its impact and assist patients to better manage the challenges of treatment.     

The Role of Reflective Functioning in Predicting Marital and Coparenting Quality

Reflective functioning (RF) is a measure of mentalization—the capacity to think about one’s own and others’ thoughts and feelings and to understand the connections between mental states and behaviors. Previous research indicates a decline in marital quality across the transition to parenthood, and some studies have found that parents are less happy than non-parents. Thus, researchers have called for research into possible moderators of these patterns. RF may help couples navigate this transition by more easily taking each other’s (and the infant’s) perspective and understanding each other’s behaviors. Much of the research on RF has focused on mothering behavior; research has not yet examined associations between RF and other family interactions. We examined associations between RF and marital and coparenting quality for both wives and husbands. Reflective functioning was coded from Adult Attachment Interviews conducted during pregnancy. We assessed marital quality at 3.5 months, and coparenting quality at 13 months, after the birth of the target child. Wives’ higher RF was associated with higher levels of positive—and lower levels of negative—marital and coparenting interactions. Wives who were better able to reflect on their early experiences with their parents were involved in marital interactions that were more positive and supportive and less conflicted and undermining. Husbands’ RF did not predict marital or coparenting quality. These findings highlight the importance of reflective functioning in understanding family functioning.     

From Fathers to Sons: The Intergenerational Transmission of Parenting Behavior among African American Young Men

This study examined the intergenerational transmission of fathering among young, African American fathers in rural communities. A sample of 132 African American young men living in the rural South reported on the quality of their relationship with their biological and social fathers in the family of origin, their own involvement with their young children, and relational schemas of close, intimate relationships. Results of path analyses supported the hypothesized mediational model, such that a better relationship with one's biological (but not social) father predicted increased father involvement in the next generation, and this association was partially mediated through positive relational schema after controlling for a range of covariates. Tests of moderated mediation indicated that the link between relational schema and father involvement was significantly stronger among fathers of girls than fathers of boys. Findings highlight the unique influence of close, nurturing father–child relationships for downstream father involvement, and the role of relational schemas as a mechanism for intergenerational transmission among young, rural, African American fathers of girls.     

Direct remembering,mediated remembering,and atypical forgetting functions

Atypical forgetting functions have been demonstrated in several recent studies of delayed matching to sample, in which experimental conditions are altered partway through the retention interval. The forgetting functions are atypical in that accuracy or discriminability is not always a negatively accelerated monotonic function of increasing retention interval duration, but may increase at later times in the retention interval. Atypical forgetting functions reflect changes in levels of discrimination. A switch from a lower level to a higher level of discrimination, or vice versa, can occur at any time in the retention interval. The behavioral theories of remembering proposed by Nevin, Davison, Odum, and Shahan (2007), and White and Brown (2014), offer quantitative predictions of forgetting functions that differ in intercept or slope. Both theories are able to account for atypical forgetting functions, by assuming time‐independent changes in the mediating effect of attending to sample and comparison stimuli (in Nevin et al.'s model) or in the direct effect of the context of reinforcement of the conditional discrimination (in White & Brown's model). Despite differences in their main assumptions, the theories have an edge over any theory that assumes that forgetting is time‐dependent.     

Judging the Goring Ox: Retribution Directed Toward Animals

Prior research on the psychology of retribution is complicated by the difficulty of separating retributive and general deterrence motives when studying human offenders (Study 1). We isolate retribution by investigating judgments about punishing animals, which allows us to remove general deterrence from consideration. Studies 2 and 3 document a “victim identity” effect, such that the greater the perceived loss from a violent animal attack, the greater the belief that the culprit deserves to be killed. Study 3 documents a “targeted punishment” effect, such that the responsive killing of the actual “guilty” culprit is seen as more deserved than the killing of an almost identical yet “innocent” animal from the same species. Studies 4 and 5 extend both effects to participants' acceptance of inflicting pain and suffering on the offending animal at the time of its death, and show that both effects are mediated by measures of retributive sentiment, and not by consequentialist concerns.     

Antiegalitarians for affirmative action? When social dominance orientation is positively related to support for egalitarian social policies

Previous research has found that people high in social dominance orientation (i.e., antiegalitarians) generally oppose affirmative action policies. We propose that antiegalitarians may be less opposed to strong affirmative action policies because such policies may be perceived to ultimately strengthen racial hierarchies. Studies 1 and 2 demonstrate that antiegalitarian individuals are less opposed to affirmative action policies, as compared to egalitarian individuals, when such policies strongly weigh minority status in selection decisions. Study 3 provides evidence that antiegalitarians lessen their opposition to strong policies only when such policies are believed to enhance racial hierarchies through the recruitment of minorities that remain at the bottom of organizational hierarchies. Theoretical, political, and organizational implications are discussed.