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The severity of inferior parietal perfusion deficits in Alzheimer's disease (AD) is strongly associated with global intellectual decline. The relationship to specific losses of neuropsychological functioning, however, is less clear, as is the relative importance of the side (left vs. right) of hemispheric deficit. In this study, 53 patients with probable AD and 35 elderly controls received both a resting133Xe rCBF measurement and neuropsychological examination. AD patients demonstrated the expected bilateral deficits in inferior parietal perfusion, as well as impairment on measures of mental status, intelligence, verbal and visual memory, attention, language, and construction abilities. The severity of this bilateral parietal deficit, in turn, was associated with virtually all of these AD-related neuropsychological impairments, most strongly with declining Performance IQ. Left-sided deficits correlated better with overall declines in IQ, as well as with declining attention and language fluency. Right-sided deficits, on the other hand, correlated best with declines in mental status and—paradoxically—verbal memory and contributed independently to declines in Full Scale and Performance IQ. In terms of the number and strength of their association to neuropsychological measures, left-sided deficits appear much more predictive of cognitive decline in AD. Right-sided deficits, however, may be most important for predicting aspects of performance skill that are only indirectly assessed in standard paper-and-pencil format. Overall, it appears that both sides make significant, but independent contributions to general functional decline in AD, but that left-sided deficits are more closely associated with cognitive decline as measured by most standard neuropsychological measures. 相似文献
53.
Steven R. H. Beach Allen W. Barton Man Kit Lei Gene H. Brody Steven M. Kogan Tera R. Hurt Frank D. Fincham Scott M. Stanley 《Family process》2014,53(4):580-595
African American couples (n = 331) with children, 89% of whom were married, were assigned to either (a) a culturally sensitive couple‐ and parenting‐enhancement program (ProSAAF) or (b) an information‐only control condition in which couples received self‐help materials. Husbands averaged 41 years of age and wives averaged 39 years. We found significant effects of program participation in the short term on couple communication, which was targeted by the intervention, as well as over the long term, on self‐reported arguing in front of children. Long‐term parenting outcomes were fully mediated by changes in communication for wives, but not for husbands. For husbands, positive change depended on amount of wife reported change. We conclude that wives' changes in communication from baseline to posttest may be more pivotal for the couples' long‐term experience of decreased arguing in front of children than are husbands' changes, with wives' changes leading to changes in both partners' reports of arguments in front of children. 相似文献
54.
The Temporal Consistency of Personality Effects: Evidence from the British Household Panel Survey 下载免费PDF全文
Andrew J. Bloeser Damarys Canache Dona‐Gene Mitchell Jeffery J. Mondak Emily Rowan Poore 《Political psychology》2015,36(3):331-340
Personality traits have been posited to function as stable influences on political attitudes and behavior. Although personality traits themselves exhibit high levels of temporal stability, it is not yet known whether the effects of these traits are marked by comparable temporal consistency. To address this question, this research note examines data from Wave 13 (2003–2004), Wave 15 (2005–2006) and Wave 17 (2007–2008) of the British Household Panel Survey (BHPS). Twenty‐seven behavioral and 14 attitudinal dependent variables are studied. Consistency of effects is gauged via a series of multilevel models in which personality effects are permitted to vary by year. High levels of temporal consistency are observed for personality traits as represented by the Big Five framework. 相似文献
55.
Gene Callahan 《British Journal for the History of Philosophy》2018,26(2):396-399
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Gene Brown Unal O. Boya Neil Humphreys Robert E. Widing II 《Journal of Personal Selling & Sales Management》2013,33(1):25-33
A random sample of purchasing agents was surveyed and split into two groups based on their socializing behavior. These two groups differ as to the importance of various salesperson attributes and behaviors. It was also found that “high” socializers tend to engage in after-hour meetings and discuss non-business related topics more so than “low” socializers. In addition, “high” socializers tend to be younger, provide more time for sales meetings, have less tenure, and are more likely to be found in smaller purchasing departments compared to “low” socializers. Other findings and implications are discussed and areas for further research are suggested. 相似文献
58.
The current study explored organizational antecedents of employee engagement in a military organization. A survey was administered to junior military personnel assessing leadership effectiveness, role clarity, organizational culture, and peer group interactions as predictors of engagement. Leadership's influence on engagement was expected to be partially mediated by role clarity and organizational culture. Engagement was predicted to fully mediate the relationship between the aforementioned variables and turnover intentions. Results indicated that leadership's influence on engagement was fully mediated by role clarity and organizational culture. In addition, engagement fully mediated the relationship between all variables and turnover intentions. 相似文献
59.
Threat-related processing supports prospective memory retrieval for people with obsessive tendencies
Richard L. Marsh Gene A. Brewer John Paul Jameson Gabriel I. Cook Nader Amir Jason L. Hicks 《Memory (Hove, England)》2013,21(6):679-686
Obsessive-compulsive disorder can result in a variety of deficits to cognitive performance, including negative consequences for attention and memory performance. The question addressed in the current study concerned whether this disorder influenced performance in an event-based prospective memory task. The results from a subclinical population indicated that, relative to non-anxious controls and mildly depressed controls, people with obsessive-compulsive tendencies (washing compulsions) incur decrements in remembering to respond to cues related to a neutral intention (respond to animals). This deficit was ameliorated by giving the subclinical group an intention about a threat-related category (respond to bodily fluids) and cueing them with concepts that they had previously rated as particularly disturbing to them. Thus, their normal attentional bias for extended processing of threat-related information overcame their natural deficit in event-based prospective memory. 相似文献
60.
Gene R. Medinnus 《The Journal of genetic psychology》2013,174(1):117-118
The development of the concept of time in third, fifth, and seventh graders of two Israeli social groups—advantaged Westerners (n = 144) and disadvantaged Easterners (n = 120)—was compared. Contrary to expectations, no difference in performance was found between the social groups throughout the entire age range. In both groups performance, while far from reaching perfection, increased with age. In addition, disparity between our findings and those of Siegler and Richards cast doubts on the generalizability of the rules they extracted through the rule-assessment method. 相似文献