Neuroethics,confidentiality, and a cultural imperative in early onset Alzheimer disease: a case study with a First Nation population

The meaningful consideration of cultural practices, values and beliefs is a necessary component in the effective translation of advancements in neuroscience to clinical practice and public discourse. Society’s immense investment in biomedical science and technology, in conjunction with an increasingly diverse socio-cultural landscape, necessitates the study of how potential discoveries in neurodegenerative diseases such as Alzheimer disease are perceived and utilized across cultures. Building on the work of neuroscientists, ethicists and philosophers, we argue that the growing field of neuroethics provides a pragmatic and constructive pathway to guide advancements in neuroscience in a manner that is culturally nuanced and relevant. Here we review a case study of one issue in culturally oriented neuroscience research where it is evident that traditional research ethics must be broadened and the values and needs of diverse populations considered for meaningful and relevant research practices. A global approach to neuroethics has the potential to furnish critical engagement with cultural considerations of advancements in neuroscience.     

Volunteer Mentoring Relationships With Minority Youth: An Analysis of Same‐ Versus Cross‐Race Matches1

Despite the growth of youth mentoring programs in recent years, key questions remain regarding the relative importance of making matches on the basis of shared racial background. Both sides of the argument regarding racial matching are presented, followed by a comparison of the effects of same‐ vs. cross‐race matches involving minority youth (N= 476). Minority adolescents were less likely to report initiating alcohol when placed in cross‐race matches. In addition, minority boys in same‐race matches reported smaller decrements in scholastic competence and self‐worth than did minority boys in cross‐race matches. Minority girls in same‐race matches reported smaller decrements in school value and self‐worth than did minority girls in cross‐race matches. Youth, parent, and caseworker impressions of the 2 relationship types largely converged, but the few impressions that differed tended to favor cross‐race matches. The methodological limitations and implications of this study are discussed.     

The role of perseveration in children's symbolic understanding and skill

In the first few years of life, children become increasingly sensitive to the significance of a variety of symbolic artifacts. An extensive body of research has explored very young children's ability to use symbol‐based information as a guide to current reality. In one common task, for example, children watch as a miniature toy is hidden in a scale model, and are then asked to retrieve a larger version of the toy from the corresponding place in the room itself. Two‐and‐a‐half‐year‐old children perform very poorly in most versions of this task. Their most common error is to perseverate; that is, they search again at the location where the toy was last hidden. Two studies examined the degree to which 2¹/₂‐year‐olds’ high rate of perseveration and poor performance stem from problems with inhibitory control. Results showed that problems with inhibitory control contribute very little to 2¹/₂‐year‐old children's difficulty with the task. Instead, the results confirm young children's great difficulty appreciating and exploiting symbol–referent relations.     

Personality traits, perceived risk, and risk-reduction behaviors: a further study of smoking and radon.

Personality traits and risk perceptions were examined as predictors of changes in smoking behavior. Participants (N = 697) were part of a randomized controlled trial of interventions to reduce exposure to the combined hazard of radon and cigarette smoke. Participants with higher perceived risk at baseline for the combination of smoking and radon were more likely to have a more restrictive household smoking ban in place at 12-month follow-up (p < .05). Risk perceptions also predicted reductions in the total number of cigarettes smoked in the home for participants in the video intervention who had high or moderate levels of extraversion (p < .01). Greater perceived risk predicted whether highly or moderately conscientious women quit smoking (p < .05). The moderating effects of personality traits should be considered when evaluating risk-reduction interventions.