ELSI priorities for brain imaging

As one of the most compelling technologies for imaging the brain, functional MRI (fMRI) produces measurements and persuasive pictures of research subjects making cognitive judgments and even reasoning through difficult moral decisions. Even after centuries of studying the link between brain and behavior, this capability presents a number of novel significant questions. For example, what are the implications of biologizing human experience? How might neuroimaging disrupt the mysteries of human nature, spirituality, and personal identity? Rather than waiting for an ethical agenda to emerge from some unpredictable combination of the concerns of ethicists and researchers, the attention of journalists, or after controversy is sparked by research that cannot be retracted, we queried key figures in bioethics and the humanities, neuroscience, media, industry, and patient advocacy in focus groups and interviews. We identified specific ethical, legal and social issues (ELSI) that highlight researcher obligations and the nonclinical impact of the technology at this new frontier.     

An exploratory study of ethical values in nonprofit fundraising: survey of fundraising executives

An initial study used the Ethical Position Quotient in an extension of this measure from for-profit organizations to nonprofit organizations. Responses from professional fundraising executives for nonprofit organizations were generally more idealistic than relativistic regarding ethical decision-making. Additionally, in a comparison of the executives' answers to those of M.B.A. students, the students were significantly more relativistic and less idealistic than the nonprofit executives. On Forsyth's Taxonomy of Ethical Perspectives, approximately 20% of the students were absolutists versus 66% of the fundraising executives. Conversely, 70% of the M.B.A. students were situationists compared to only a third of the executives. This disparity in responses between these groups provides a rich and interesting platform for research.     

Attachment,Behavioral Inhibition,and Anxiety in Preschool Children

This study examined the association between insecure attachment, behavioral inhibition, and anxiety in an at risk sample of preschool children. The relationship between maternal anxiety and child anxiety was also assessed. Participants were 104 children aged 3–4 years who were assessed for behavioral inhibition and mother–child attachment (using the Strange Situation procedure). DSM-IV criteria were used to assess childhood anxiety disorders. Insecure attachment and behavioral inhibition were both independently associated with child anxiety, even after controlling for the effect of maternal anxiety. Maternal anxiety was also associated with child anxiety. This study identified both constitutional and environmental factors associated with the expression of anxiety in young children. Furthermore, the highest levels of anxiety were shown by children who were behaviorally inhibited and insecurely attached and whose mothers were also anxious.     

Imaging or imagining? A neuroethics challenge informed by genetics

From a twenty-first century partnership between bioethics and neuroscience, the modern field of neuroethics is emerging, and technologies enabling functional neuroimaging with unprecedented sensitivity have brought new ethical, social and legal issues to the forefront. Some issues, akin to those surrounding modern genetics, raise critical questions regarding prediction of disease, privacy and identity. However, with new and still-evolving insights into our neurobiology and previously unquantifiable features of profoundly personal behaviors such as social attitude, value and moral agency, the difficulty of carefully and properly interpreting the relationship between brain findings and our own self-concept is unprecedented. Therefore, while the ethics of genetics provides a legitimate starting point--even a backbone--for tackling ethical issues in neuroimaging, they do not suffice. Drawing on recent neuroimaging findings and their plausible real-world applications, we argue that interpretation of neuroimaging data is a key epistemological and ethical challenge. This challenge is two-fold. First, at the scientific level, the sheer complexity of neuroscience research poses challenges for integration of knowledge and meaningful interpretation of data. Second, at the social and cultural level, we find that interpretations of imaging studies are bound by cultural and anthropological frameworks. In particular, the introduction of concepts of self and personhood in neuroimaging illustrates the interaction of interpretation levels and is a major reason why ethical reflection on genetics will only partially help settle neuroethical issues. Indeed, ethical interpretation of such findings will necessitate not only traditional bioethical input but also a wider perspective on the construction of scientific knowledge.     

Chronic Auditory Agnosia Following Landau-Kleffner Syndrome: A 23 Year Outcome Study

We report a 27-year-old woman with chronic auditory agnosia following Landau-Kleffner Syndrome (LKS) diagnosed at age 4 1/2 . She grew up in the hearing/speaking community with some exposure to manually coded English and American Sign Language (ASL). Manually coded (signed) English is her preferred mode of communication. Comprehension and production of spoken language remain severely compromised. Disruptions in auditory processing can be observed in tests of pitch and duration, suggesting that her disorder is not specific to language. Linguistic analysis of signed, spoken, and written English indicates her language system is intact but compromised because of impoverished input during the critical period for acquisition of spoken phonology. Specifically, although her sign language phonology is intact, spoken language phonology is markedly impaired. We argue that deprivation of auditory input during a period critical for the development of a phonological grammar and auditory–verbal short-term memory has limited her lexical and syntactic development in specific ways.     

Evaluating teaching and students’ learning of academic research ethics

A team of philosophers and scientists at Dartmouth College worked for three years to create, train faculty and pilot test an adequate and exportable class in research methods for graduate students of science and engineering. Developing and testing methods for evaluating students’ progress in learning research ethics were part of the project goals. Failure of methods tried in the first year led to the refinement of methods for the second year. These were used successfully in the pilot course and in one university setting external to Dartmouth. The process of development and justification for the final methods are discussed here.     

Experience of group work in counsellor training and preferred learning styles

Not all those experiencing group work as part of counsellor training appear to like or benefit from it. Here an attempt is ma& to identity individuals, categorized by preferred learning style, that might not make effective use of this learning opportunity. Questionnaires measuring preferences for learning styles and experience of group work were received from 37 students on a postgraduate counselling course. Significant differences in perception of group work were found to be correlated with preferred learning style.     

The business of ivory tower research: Paradigms for university-corporate partnerships

A university research team in a department of Counseling Psychology initiated three university/industry collaborative projects. While studying quality of work life in the hotel industry, nurse job satisfaction in the health care industry and assertive behavior in the banking industry the research team contributed its academic objectivity and research skills to these clients. At the same time the university received the benefit of a laboratory work environment, as well as the opportunity to apply academic theory. Both parties in the three partnerships benefitted from the collaboration.