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191.
RM Sapolsky 《Stress (Amsterdam, Netherlands)》1996,1(1):1-19
An extensive literature demonstrates that glucocorticoids (GCs), the adrenal steroids secreted during stress, can have a broad range of deleterious effects in the brain. The actions occur predominately, but not exclusively, in the hippocampus, a structure rich in corticosteroid receptors and particularly sensitive to GCs. The first half of this review considers three types of GC effects: a) GC-induced atrophy, in which a few weeks' exposure to high GC concentrations or to stress causes reversible atrophy of dendritic processes in the hippocampus; b) GC neurotoxicity where, over the course of months, GC exposure kills hippocampal neurons; c) GC neuroendangerment, in which elevated GC concentrations at the time of a neurological insult such as a stroke or seizure impairs the ability of neurons to survive the insult. The second half considers the rather confusing literature as to the possible mechanisms underlying these deleterious GC actions. Five broad themes are discerned: a) that GCs induce a metabolic vulnerability in neurons due to inhibition of glucose uptake; b) that GCs exacerbate various steps in a damaging cascade of glutamate excess, calcium mobilization and oxygen radical generation. In a review a number of years ago, I concluded that these two components accounted for the deleterious GC effects. Specifically, the energetic vulnerability induced by GCs left neurons metabolically compromised, and less able to carry out the costly task of containing glutamate, calcium and oxygen radicals. More recent work has shown this conclusion to be simplistic, and GC actions are shown to probably involve at least three additional components: c) that GCs impair a variety of neuronal defenses against neurologic insults; d) that GCs disrupt the mobilization of neurotrophins; e) that GCs have a variety of electrophysiological effects which can damage neurons. The relevance of each of those mechanisms to GC-induced atrophy, neurotoxicity and neuroendangerment is considered, as are the likely interactions among them. 相似文献
192.
Cole Jonathan Gallagher Shaun McNeill David 《Phenomenology and the Cognitive Sciences》2002,1(1):49-67
Empirical studies of gesture in a subject who has lost proprioception and the sense of touch from the neck down show that specific aspects of gesture remain normal despite abnormal motor processes for instrumental movement. The experiments suggest that gesture, as a linguistic phenomenon, is not reducible to instrumental movement. They also support and extend claims made by Merleau-Ponty concerning the relationship between language and cognition. Gesture, as language, contributes to the accomplishment of thought. 相似文献
193.
The current study examined the interactive effects of an environment high in political decision making and political skill on job satisfaction. We predicted that as perceptions of political decision making increase, the satisfaction of individuals low in political skill would decrease. Conversely, the negative effects of political decision making on job satisfaction would be minimized among individuals high in political skill. Data were gathered from 105 managerial employees of a financial‐services organization. Results provided strong support for the hypothesized political decision‐making/political‐skill relationship. Implications, strengths and limitations, and avenues for future research are discussed. 相似文献
194.
Shaun Gallagher 《Continental Philosophy Review》2008,41(2):163-178
The embodied, embedded, enactive, and extended approaches to cognition explicate many important details for a phenomenology
of perception, and are consistent with some of the traditional phenomenological analyses. Theorists working in these areas,
however, often fail to provide an account of how intersubjectivity might relate to perception. This paper suggests some ways
in which intersubjectivity is important for an adequate account of perception.
相似文献
Shaun GallagherEmail: |
195.
Mental Institutions 总被引:1,自引:0,他引:1
We propose to extend Clark and Chalmer’s concept of the extended mind to consider the possibility that social institutions
(e.g., legal systems, museums) may operate in ways similar to the hand-held conveniences (notebooks, calculators) that are
often used as examples of extended mind. The inspiration for this suggestion can be found in the writings of Hegel on “objective
spirit” which involves the mind in a constant process of externalizing and internalizing. For Hegel, social institutions are
pieces of the mind, externalized in their specific time and place. These institutions are the products of shared mental processes.
We then use these institutions instrumentally to do further cognitive work, for example, to solve problems or to control behavior.
相似文献
Shaun GallagherEmail: |
196.
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198.
Eugene V. Gallagher 《Teaching Theology & Religion》2009,12(1):24-36
The first seven volumes of the American Academy of Religion's “Teaching Religious Studies” series provide informative glimpses of how teachers in very different contexts understand the intellectual decisions, strategies, and actions that constitute their craft. Although individual volumes have different formats, the dominant image of good teaching that emerges is that it is founded on deep and sophisticated knowledge of the particular subject matter. Beyond that, many essays provide instructive anatomies of particular syllabi, moments in the classroom, or other aspects of teaching. Much of the material in the essays comes from reflective practitioners and there is relatively little sustained engagement with the contemporary literature on teaching and learning. Nonetheless, virtually any teacher can find in these volumes stimulating reflections on the intersections of substantive research and pedagogy in a variety of classroom contexts. 相似文献
199.
The Art of God: The Making of Christians and the Meaning of Worship. By
Christopher Irvine. Pp. xii, 148, Chicago,Liturgy Training Publications. 2006, $8.95.
The Substance of Things Seen: Art,Faith, and the Christian Community. By
Robin M. Jensen. Pp. xi, 152, Grand Rapids/Cambridge,Eerdmans, 2004, $15.93.
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Daniel B. Gallagher 《Heythrop Journal》2017,58(6):971-972
200.
Matthew W. Gallagher Susana C. Marques Shane J. Lopez 《Journal of Happiness Studies》2017,18(2):341-352
Previous longitudinal studies of student hope have established a connection between how people think about the future and their college achievement. This study examined the role of hope in predicting the achievement and retention of college students while controlling for educational history and two other psychological constructs, academic self-efficacy and engagement. Hope, self-efficacy, engagement were all correlated with both the number of semesters enrolled and cumulative grade point averages (GPAs) for the first 4 years of college. Hope was the only factor that had unique effects when examining predictors simultaneously and controlling for academic history. Hope uniquely predicted the number of enrolled semesters, whether students returned for the 2nd semester of college, whether students graduated in 4 years, and students’ GPAs across 4 years of college. Results therefore indicate that hope was the most robust predictor of academic achievement in college after controlling for educational history. These findings point to a need to help students develop the capacity to initiate and sustain movement toward goals in the pursuit of higher academic achievement. 相似文献