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CF-1 male mice were trained in an inhibitory avoidance task using a high footshock (1,2 mA, 50 Hz, 1 sec) in order to reduce the influence of extinction on retention performance. At 2, 7, 14, or 30 d after training, the first retention test was performed and hemicholinium (HC-3, 1.0 microg/mice), a specific inhibitor of high-affinity choline uptake in brain cholinergic neurons, was given intracerebroventricularly immediately after. Twenty four hours after treatment, mice were tested in an inhibitory avoidance task during five consecutive days, each 24 h apart. Retention performance was impaired by HC-3 when the first re-exposure took place at 2, 7, or 14 d, but the effect was no longer seen when re-exposure occurred 30 d after training. We did not find spontaneous recovery 21 d after training, when memory was retrieved 2 d after training and HC-3 was given immediately after. Although we cannot definitively discard a retrieval deficit, this lack of spontaneous recovery is in accordance with the storage-deficit interpretation. These results confirm and extend previous ones, suggesting that central cholinergic mechanisms are involved in the hypothetical reconsolidation memory processes of an inhibitory avoidance task in mice and also suggest that this participation depends on the "age" of the original memory trace. This implies that the vulnerability of a reactivated memory to a specific treatment, as the one used in this study, inversely correlates with the age of the original memory, and it is likely to determine memory reconsolidation processes.  相似文献   
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A multiple baseline across settings was used to evaluate the effects of differential reinforcement of alternative behavior, nonremoval of the fork ( Hoch, Babbitt, Coe, Krell, & Hackbert, 1994 ), and stimulus fading on consumption of food rejected previously. The study was conducted in two separate settings, and caregivers were trained in the intervention technique to increase generalization to natural settings. Food variety increased in both settings.  相似文献   
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The objective of this study was to compare, through a Confirmatory Factor Analysis, two different theoretical models that explain the operationalized creativity construct with the Verbal Torrance Tests of Creative Thinking (TTCT), Form B. Model 1 is represented by six factors which correspond to each activity and its respective indicators while Model 2 is integrated by three factors which correspond to each TTCT ability (i.e., Fluency, Originality, and Flexibility) and the corresponding indicators for each variable. The study was carried out with a sample consisting of 432 Spanish‐speaking youngsters of both sexes aged 15–26. According to the research findings, the model which showed the most satisfactory fit identifies six correlated factors that correspond to each of the activities proposed (χ2 = 414.48; df = 116; χ2/df = 3.57; GFI = .90; NFI = .95; CFI = .96 and RMSEA = .077). These results are discussed according to its psychometric implications for the construct assessment in different fields.  相似文献   
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This study evaluated the association between sexual victimization history, posttraumatic stress symptoms, and women’s decision making in social situations, and whether ethnicity moderated these associations. Participants were 334 undergraduate women between ages 18 and 24. The sample was diverse ethnically (Non-Hispanic white, n = 177; Hispanic, n = 157) and composed primarily of freshman, single women. Stimuli were written vignettes describing social situations that varied in their degree of victimization risk. Participants completed tasks that assessed their ability to generate and select responses to the situations, as well as their perceived efficacy in executing responses. They then completed the Sexual Experiences Survey to quantify the severity of victimization experiences and the PTSD Checklist – Civilian Version to measure symptoms of posttraumatic stress. Structural equation modeling (SEM) of women’s decision making revealed that more severe victimization history and greater posttraumatic stress symptoms were associated with less effective response generation, and greater posttraumatic stress symptoms was associated with reduced perceived efficacy in executing effective responses. Ethnicity also moderated the effect of victimization history on perceived efficacy. For Non-Hispanic White women, more severe victimization history was related to less effective response generation and perceived efficacy when considering responses, while for Hispanic women, victimization history was unrelated to both decision making processes. This study emphasizes the importance of decision making as it relates to women’s victimization risk. These processes, as well as the influence of ethnicity on women’s decision making, appear relevant to consider when developing preventative interventions for college women.  相似文献   
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Depressed individuals are less reactive than healthy individuals to positive stimuli in the laboratory, but accumulating evidence suggests that they are more emotionally reactive to positive events in their daily lives. The present study probed the boundaries of this curious “mood brightening” effect and investigated its specificity to major depressive disorder (MDD) vis-à-vis generalized anxiety disorder (GAD), its closest boundary condition. We used ecological momentary assessment to measure reactions to positive events over one week in individuals with MDD (n = 38), GAD (n = 36), comorbid MDD-GAD (n = 38), and no psychopathology (n = 33). Depressed individuals responded to positive events with larger changes in affect, cognition, reported withdrawal (but not approach) behavior, and symptoms than healthy controls. More severe depression assessed before the sampling week predicted greater brightening. Altered reactivity to positive events was relatively specific to MDD when compared with GAD, similar to patterns found for other positive emotional processes. The robustness, scope, and relative specificity of the brightening effect highlights the need to resolve conflicting findings across laboratory and non-laboratory studies to advance understanding of altered reactivity in emotional disorders.  相似文献   
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This is the first of two reports of a study using semi‐structured, in‐depth interviews to explore the current and recollected experiences of Irish people for the period before, during, and after the introduction of euro notes and coins (1 January 2002). Twenty‐four adults, 12 males and 12 females, covering a range of ages and educational attainment, were interviewed between October 2002 and February 2003. We found that most had welcomed the new currency initially, though some had felt less positive about it, whilst current experiences were more mixed. People's explanations for their attitudes seemed to focus more on the economic and practical aspects of currency change rather than symbolic meanings. Initially, most had experienced a euro illusion (prices in euros seeming to be more expensive than in punts). However, for most, the strength of the illusion appeared to diminish quite quickly. Nonetheless, current prices were believed to be higher, and many respondents attributed this either directly or indirectly to the change of currency. Although independent evidence found that there had been price increases in certain sectors, it was concluded that perceived price rises were, in part, illusory, and driven by expectations and selective price monitoring. Copyright © 2005 John Wiley & Sons, Ltd.  相似文献   
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