Intertemporal choice--toward an integrative framework

Intertemporal choices are decisions with consequences that play out over time. These choices range from the prosaic--how much food to eat at a meal--to life-changing decisions about education, marriage, fertility, health behaviors and savings. Intertemporal preferences also affect policy debates about long-run challenges, such as global warming. Historically, it was assumed that delayed rewards were discounted at a constant rate over time. Recent theoretical and empirical advances from economic, psychological and neuroscience perspectives, however, have revealed a more complex account of how individuals make intertemporal decisions. We review and integrate these advances. We emphasize three different, occasionally competing, mechanisms that are implemented in the brain: representation, anticipation and self-control.     

Emotionally controlled decision-making and a gene variant related to serotonin synthesis in women with borderline personality disorder

The Iowa Gambling Task (IGT) was used to examine (i) social decision-making in women with borderline personality disorder (BPD), and (ii) the relationship between impaired decision-making and the tryptophan hydroxylase-1 (TPH-1) gene, involved in serotonin synthesis. Forty-two women with BPD and a history of suicide attempts were genotyped, and the frequency of a TPH-1 haplotype previously uniquely associated with BPD was calculated. The BPD group scored significantly lower than a control group in the IGT. Furthermore, the TPH-1 haplotype displayed a significantly higher frequency in BPD participants with impaired decision making, compared to BPD participants with normal scores. These findings suggest that impaired decision-making as determined by the IGT is a feature of BPD and may be (i) associated with serotonin dysfunction, and (ii) possibly relevant for suicidal behavior.     

Internet addiction among Norwegian adults: a stratified probability sample study

Most Norwegians are Internet users. We conducted a stratified probability sample study (Norway, 2007, age-group 16–74 years, N = 3,399, response rate 35.3%, 87.1% Internet users) to assess the prevalence of Internet addiction and at-risk Internet use by the Young Diagnostic Questionnaire (YDQ). The prevalence of Internet addiction (YDQ score 5–8) was 1.0% and an additional 5.2% were at-risk Internet users (YDQ score 3–4). Internet addiction and at-risk Internet use was strongly dependent on gender and age with highest prevalences among young males (16–29 years 4.1% and 19.0%, 30–39 years 3.3% and 10.7%). Logistic regression showed that male gender, young age, university level education, and an unsatisfactory financial situation were factors positively associated with "problematic Internet use" (at-risk and addicted use combined). Time spent on the Internet and prevalence of self-reported sleeping disorders, depression, and other psychological impairments increased linearly with YDQ score. Problematic Internet use clearly affects the lives of many people.     

A systematic examination of different parameters of presession exposure to tangible stimuli that maintain problem behavior

We examined the effects of three different presession conditions on tangibly maintained problem behavior for 2 students with autism, using individual-participant multielement designs. First, an analogue functional analysis demonstrated that problem behavior was maintained by access to tangible items. Next, topographies of item rejection were identified. Finally, students were exposed to (a) brief access, (b) no access, and (c) satiation to the tangible items prior to tangible sessions. The results demonstrated high levels of problem behavior following the brief-access and no-access presession conditions and low levels of problem behavior following the satiation condition. The findings are discussed in the context of how satiation might best be defined for these sorts of evaluations.     

Relationships between individualism-collectivism, gender, and direct or indirect aggression: a study in China, Poland, and the US

Direct and indirect aggression were studied in college students from China (women n=122; men n=97), a highly collectivistic culture; the US (women n=137; men n=136), a highly individualistic culture; and Poland (women n=105; men n=119), a culture with intermediate levels of collectivism and individualism. Consistent with a hypothesis derived from national differences in relative levels of collectivism and individualism, both direct and indirect aggression were higher in the US than in Poland and higher in Poland than in China. The theoretical implication of these results and directions for future research were discussed.     

Dynamics of expertise level: Coordination in handstand

The aim of the present study was to investigate the effect of expertise on coordination patterns. We thus tested the coordination dynamics of two groups: experts in the handstand also having high expertise in gymnastics and experts in the handstand but only intermediate expertise in gymnastics. All participants were instructed to track a target with their ankles while maintaining the handstand. The target moved on the anterior-posterior axis according to three frequency conditions: 0.2, 0.4 and 0.6 Hz. The results showed that the suprapostural task was performed better by the group with high gymnastics expertise. Moreover, the spontaneous coordination was specific to the level of gymnastics expertise. We concluded that (i) the dynamics of coordination progress with the overall level of expertise in a sport discipline, independently of the mastery of a single skill, (ii) persistence and change are seen in related movement properties, and (iii) high expertise offers greater adaptability relative to the task.     

Visual pathway deficit in female fragile X premutation carriers: a potential endophenotype

Previous studies indicated impaired magnocellular (M) and relatively spared parvocellular (P) visual pathway functioning in patients with fragile X syndrome. In this study, we assessed M and P pathways in 22 female fragile X premutation carriers with normal intelligence and in 20 healthy non-carrier controls. Testing procedure included visual contrast sensitivity and vernier threshold measurements. Results revealed that carriers were selectively impaired on tests of M pathways (low spatial/high temporal frequency contrast sensitivity and frequency-doubling vernier), whereas they showed intact performance on P pathway tests. These results suggest that the deficit of the M pathway is an endophenotype of fragile X syndrome.     

Differences in adrenocortical secretory and gene expression responses to stimulation in vitro by ACTH or prolactin between high- and low-avoidance Hatano rats

Rats of the Hatano high-avoidance (HAA) and low-avoidance (LAA) strains have been genetically selected on the basis of their two-way active avoidance behavior, and have different endocrine responses to stress. The present study focused on the adrenal steroid hormone responses of the Hatano strains and identifies differences in regulation of the adrenal cortex in vitro of HAA and LAA rats. Although incubation with prolactin (PRL) and/or adrenocorticotrophic hormone (ACTH) resulted in a dose-dependent increase of corticosterone and progesterone release by adrenal cells from both HAA and LAA male rats, the responses were markedly increased for adrenal cells from LAA rats as compared with HAA rats. This finding suggested that adrenal glands of HAA rats are less sensitive to PRL and/or ACTH than adrenals from LAA rats. Several possible intra-adrenal regulators were investigated. The basal level of expression of steroidogenic acute regulatory protein (StAR) and the long form of the PRL receptor (PRLR-L) mRNAs was higher in adrenals of LAA rats. ACTH treatment of adrenal cells from HAA rats resulted in statistically significant increases in melanocortin receptor 2 (MC2R) mRNA expression, while neither ACTH nor PRL altered MC2R mRNA expression in adrenal cells of LAA rats. Conversely, the increase in PRLR-L mRNA expression induced by PRL was observed only in adrenal cells from LAA rats. Treatment of adrenal cells with PRL and/or ACTH increased the expression of StAR and CYP11A1 mRNAs for both Hatano strains. However, the induction of StAR mRNA expression was higher in LAA rats, but the CYP11A1 response was lower. These findings indicate that adrenal cells of the LAA strain have higher sensitivity to secretagogues than those of the HAA strain. These results suggest that PRL may also be important in stimulating secretion of adrenal steroid hormones.     

“我永远不会去天堂”--亚伯拉罕·林肯的宗教怀疑主义

本文通过亚伯拉罕·林肯的家人、亲属、邻居、朋友及政治伙伴等不同人的回忆和口述,呈现出了林肯个人在生活中和政治生涯中对于宗教,信仰所持的怀疑的态度和做法,勾勒出林肯作为一个非宗教信仰者的人生轨迹。