Should assisted dying be legalised?

When an individual facing intractable pain is given an estimate of a few months to live, does hastening death become a viable and legitimate alternative for willing patients? Has the time come for physicians to do away with the traditional notion of healthcare as maintaining or improving physical and mental health, and instead accept their own limitations by facilitating death when requested? The Universities of Oxford and Cambridge held the 2013 Varsity Medical Debate on the motion “This House Would Legalise Assisted Dying”. This article summarises the key arguments developed over the course of the debate. We will explore how assisted dying can affect both the patient and doctor; the nature of consent and limits of autonomy; the effects on society; the viability of a proposed model; and, perhaps most importantly, the potential need for the practice within our current medico-legal framework.     

When hoarding is a symptom of OCD: A case series and implications for DSM-V

Hoarding, the excessive collection and failure to discard objects of apparently little value, can represent a serious psychiatric problem and pose a threat to public health. Hoarding has traditionally been considered a symptom (or symptom dimension) of Obsessive-Compulsive Disorder (OCD), but its nosological status has recently been debated. Mounting evidence suggests that, once other primary causes are ruled out, hoarding may be a discrete diagnostic entity, recently named Hoarding Disorder. However, hoarding can sometimes be a genuine OCD symptom. This can be confusing and clinicians may sometimes struggle making the differential diagnosis. To illustrate this, we describe 10 OCD patients with severe hoarding behavior that is better conceptualized as a symptom of OCD. We focus on the motivations for hoarding and the overlapping of hoarding with other obsessive-compulsive symptom dimensions. We estimate that this clinical presentation is relatively rare and accounts for a minority of severe hoarding cases. We discuss the unique characteristics of hoarding as a symptom of OCD and the implications for DSM-V.     

The Roman state and genetic pacification

Over the last 10,000 years, the human genome has changed at an accelerating rate. The change seems to reflect adaptations to new social environments, including the rise of the State and its monopoly on violence. State societies punish young men who act violently on their own initiative. In contrast, non-State societies usually reward such behavior with success, including reproductive success. Thus, given the moderate to high heritability of male aggressiveness, the State tends to remove violent predispositions from the gene pool while favoring tendencies toward peacefulness and submission. This perspective is applied here to the Roman state, specifically its long-term effort to pacify the general population. By imperial times, this effort had succeeded so well that the Romans saw themselves as being inherently less violent than the "barbarians" beyond their borders. By creating a pacified and submissive population, the empire also became conducive to the spread of Christianity-a religion of peace and submission. In sum, the Roman state imposed a behavioral change that would over time alter the mix of genotypes, thus facilitating a subsequent ideological change.     

Race Relations on Prime Time Television Reconsidered: Patterns of Continuity and Change

This study was designed to assess the changes that have occurred in the portrayals of black people and cross-racial relationships in prime-time television broadcasting during the past decade. By replicating the content analysis procedures used by Weigel, Loomis, and Soja (1980), this investigation provided a consistent basis for comparing two similar samples of television content drawn, respectively, from 1978 and 1989. Results of this comparison indicated that, although black appearances and cross-racial interactions were no more frequent in the 1989 sample of product commercials, the black presence in prime-time programming had increased substantially. As compared to 1978, the proportion of time that one or more black characters were on the screen more than doubled, while the frequency of cross-racial interactions more than tripled in the 1989 sample. Nevertheless, ratings of qualitative dimensions of these cross-racial interactions suggested that relationships between blacks and whites on television continued to be portrayed as cooperative but emotionally detached, particularly when the relationships occurred outside of the work place.     

Orthographic and phonological computation in visual word recognition: Evidence from backward masking in Hebrew

We employed the backward masking paradigm to map the early computation involved in the perception of printed words in Hebrew. By independently manipulating orthographic and phonological overlap between targets and masks, we examined whether orthographic and phonological structure imposes late or early constraints on lexical access. The results demonstrated that the probability of reinstating a masked target depended on both the orthographic and the phonological overlap between the target and the mask. However, whereas phonemic structure seems to constrain lexical access only at short exposure durations, orthographic overlap also exerts its influence at longer durations.     

La langue et les Lèvres: cross-language influences on bimodal speech perception.

Previous research in speech perception has yielded two sets of findings which are brought together in the present study. First, it has been shown that normal hearing listeners use visible as well as acoustical information when processing speech. Second, it has been shown that there is an effect of specific language experience on speech perception such that adults often have difficulty identifying and discriminating non-native phones. The present investigation was designed to extend and combine these two sets of findings. Two studies were conducted using six consonant-vowel syllables (/ba/, /va/, /alpha a/, /da/, /3a/, and /ga/ five of which occur in French and English, and one (the interdental fricative /alpha a/) which occurs only in English. In Experiment 1, an effect of specific linguistic experience was evident for the auditory identification of the non-native interdental stimulus by French-speakers. In Experiment 2, it was shown that the effect of specific language experience extends to the perception of the visible information in speech. These findings are discussed in terms of their implications for our understanding of cross-language processes in speech perception and for our understanding of the development of bimodal speech perception.     

Functional neuroimaging studies of reading and reading disability (developmental dyslexia)

Converging evidence from a number of neuroimaging studies, including our own, suggest that fluent word identification in reading is related to the functional integrity of two consolidated left hemisphere (LH) posterior systems: a dorsal (temporo-parietal) circuit and a ventral (occipito-temporal) circuit. This posterior system is functionally disrupted in developmental dyslexia. Reading disabled readers, relative to nonimpaired readers, demonstrate heightened reliance on both inferior frontal and right hemisphere posterior regions, presumably in compensation for the LH posterior difficulties. We propose a neurobiological account suggesting that for normally developing readers the dorsal circuit predominates at first, and is associated with analytic processing necessary for learning to integrate orthographic features with phonological and lexical-semantic features of printed words. The ventral circuit constitutes a fast, late-developing, word identification system which underlies fluent word recognition in skilled readers.     

Conscientiousness as a Predictor of Productive and Counterproductive Behaviors

This article extends the integrity testing literature by examining relationships between conscientiousness subscales and productive and counterproductive workplace behaviors. Correlational analyses (n = 359 employees) indicated conscientiousness predicted overall performance, supervisors' willingness to rehire and employee attendance, but not integrity/safety ratings. Conscientiousness subscales differentially predicted criteria and were more parsimonious.     

Processing lexical ambiguity and visual word recognition in a deep orthography

We investigated the effect of semantic and phonemic ambiguity on lexical decision and naming performance in the deep Hebrew orthography. Experiment 1 revealed that lexical decisions for ambiguous consonant strings are faster than those for any of the high- or low-frequency voweled alternative meanings of the same strings. These results suggested that lexical decisions for phonemically and semantically ambiguous Hebrew consonant strings are based on the ambiguous orthographic information. However, a significant frequency effect for both ambiguous and unambiguous words suggested that if vowels are present, subjects do not ignore them completely while making lexical decisions. Experiment 2 revealed that naming low-frequency voweled alternatives of ambiguous strings took significantly longer than naming the high-frequency alternatives or the unvoweled strings without a significant difference between the latter two string types. Voweled and unvoweled unambiguous strings, however, were named equally fast. We propose that semantic and phonological disambiguation of unvoweled words in Hebrew is achieved in parallel to the lexical decision, but is not required by it. Naming Hebrew words usually requires a readout of phonemic information from the lexicon.