Temporally graded,context-specific retrograde amnesia and its alleviation by context preexposure: effects of postconditioning exposures to morphine in the rat

Five experiments studied retrograde impairments in Pavlovian fear conditioning following prolonged exposure to the opioid receptor agonist morphine. Injections of morphine commencing 1-7 days but not 14 days after conditioning produced amnesia for that conditioning episode. This amnesia was (a) selective such that morphine impaired freezing to the conditioning context but not to the auditory conditioned stimulus, (b) independent of the interval between the last injection of morphine and test, and (c) accompanied by a failure of contextual discrimination. Context preexposure protected context conditioning and discrimination from the amnestic effects of morphine. These results show that retrograde deficits in contextual fear conditioning are mediated by failures to consolidate a contextual representation.     

Psychological assessment in Asia: introduction to the special section

Psychological assessment with Asians is an important topic not only for psychologists from Asian countries but also for psychologists in multicultural societies with large populations of ethnic Asians. There is a dearth of information in the English language literature on psychological assessment for Asians. This special section is organized to review various forms of psychological assessment in Asia. The objectives of the special section are to inform test users and researchers of the issues related to cross-cultural validity of psychological assessment in Asia and to introduce examples of adapted and indigenously developed instruments that are culturally appropriate.     

Evaluating the latent structure of the MMPI-2 F(p) scale in a forensic sample: a taxometric analysis

P. A. Arbisi and Y. S. Ben-Porath (1995) originally proposed that the Infrequency Psychopathology scale, F(p), be used as the final step in an algorithm to determine the validity of a Minnesota Multiphasic Personality Inventory-2 (MMPI-2) protocol. The current study used taxometric procedures to determine the latent structure of F(p) among examinees with profiles that would necessitate the interpretation of F(p) when using Arbisi and Ben-Porath's proposed algorithm. Participants included a subsample of 289 consecutively referred pretrial forensic examinees adjudicated incompetent to stand trial with high Infrequency (F) scale scores, thereby providing a sample that would be expected to have a high base rate of persons with bona fide psychopathology and persons with incentive to overreport psychopathology. Using MAMBAC and MAXEIG, F(p) produced a taxonic latent structure within the subgroup of examinees who obtained raw scores on F of greater than 17. These results support Arbisi and Ben-Porath's original proposal to use F(p) to identify a distinct subgroup of overreported MMPI-2 protocols within forensic psychiatric examinees with high elevations on F. Implications and suggestions for future research are provided.     

Color naming, lens aging, and grue: what the optics of the aging eye can teach us about color language

Many languages without separate terms for green and blue are or were spoken in locations receiving above-average exposure to ultraviolet-B (UV-B) radiation. It has been proposed that this correlation is caused by premature lens aging. This conclusion was supported by an experiment in which younger observers used the term "blue" less often when they described simulated paint chips filtered through the equivalent of an older observer's lens-removing much short-wavelength light-than when they described the unfiltered versions of the same paint chips. Some stimuli that were called "blue" without simulated aging were called "green" when filtered. However, in the experiment reported here, we found that the proportion of "blue" color-name responses did not differ between younger subjects and older observers with known ocular media optical densities. Color naming for stimuli that were nominally green, blue-green, or blue was virtually identical for older and younger observers who viewed the same (unfiltered) stimuli. Our results are inconsistent with the lens-brunescence hypothesis.     

The phonological loop in task alternation and task repetition

It has recently been proposed that task repetition is easier than task alternation because the appropriate task settings are already present in working memory, whereas during task alternation task settings must be retrieved from long-term memory (Mayr & Kliegl, 2000). The present study tested whether the phonological loop is involved in keeping the relevant task settings active in working memory. It may then be expected that concurrent articulatory suppression would diminish the facilitation associated with task repetition because the phonological loop could no longer maintain the appropriate task settings active in working memory. Both during task repetition and task alternation the relevant task settings should then be retrieved from long-term memory. Three dual-task experiments were conducted. The results of Experiment 1 were in support of our prediction. Experiment 2 replicated the findings of Experiment 1 and showed that the task settings probably represent the adequate response mappings. Experiment 3 ruled out the involvement of the visuo-spatial sketchpad and more general coordination demands during dual tasking.     

Inferential confusion in obsessive-compulsive disorder: the inferential confusion questionnaire

The current article represents the further validation of the construct of inferential confusion amongst clinical samples. Inferential confusion is proposed to be a meta-cognitive confusion particularly relevant to obsessive compulsive disorder (OCD) that leads a person to confuse an imagined possibility with an actual probability. As such, it conceptualizes OCD as a form of belief disorder similar to a delusion or overvalued idea that is a product of distorted reasoning processes. In contrast, other cognitive models of OCD emphasize a phobic model of development in OCD, and thus consider the exaggerated interpretation of intrusions as an essential element in OCD. The present study administered a revised version of the Inferential Confusion Questionnaire, and the Obsessive Belief Questionnaire (OBQ), to a total of 183 participants in three clinical groups and a non-clinical control group. Results suggest that OCD, at least in part, follows a non-phobic model of development with inferential confusion significantly related to obsessive-compulsive symptoms independently of cognitive domains as measured by the OBQ, and mood states. Further, scores on inferential confusion were particularly high in those with OCD and delusional disorder as compared to anxious and non-clinical controls.     

Clinically useful,research validated assessment of persons with alcohol problems

Advances in treatment approaches available for persons with alcohol problems, particularly the advent of cognitive behavioral and motivational approaches, have made systematic assessment of these problems more important than ever for clinicians. There is a plethora of assessment instruments available, and it is a difficult task for clinicians to conceptualize, select and use these instruments in a coherent fashion. Particularly important in this task is the identification of research validated instruments that provide both clinically useful and psychometrically sound data. This paper presents a model of alcohol assessment and reviews selected research validated instruments that can be assembled into an assessment battery that provides useful data to guide treatment of alcohol problems while also addressing practical concerns encountered by clinicians in practice.     

A Review of Diagnostic Techniques in the Differential Diagnosis of Epileptic and Nonepileptic Seizures

The diagnosis of psychogenic nonepileptic seizures (PNES) is complex. Long-term electroencephalogram monitoring with video recording (video EEG) is the most common method of differential diagnosis of epilepsy and PNES. However, video EEG is complex, costly, and unavailable in some areas. Thus, alternative diagnostic techniques have been studied in the search for a diagnostic method that is as accurate as video EEG, but more cost effective, convenient, and readily available. This paper reviews the literature regarding possible diagnostic alternatives and organizes findings into 7 areas of study: demographic and medical history variables, seizure semiology, provocative testing, prolactin levels, single photon emission computed tomography, psychological testing, and neuropsychological testing. For each area, the literature is summarized, and conclusions about the accuracy of the technique as a diagnostic tool are drawn. Overall, it appears unlikely that any of the reviewed alternative techniques will replace video EEG monitoring; rather they may be more successful as complementary diagnostic tools. An important focus for further investigations involves combinations of diagnostic techniques for the differential diagnosis of epilepsy and PNES.     

Visual implicit memory in the left hemisphere: evidence from patients with callosotomies and right occipital lobe lesions

Identification of visually presented objects and words is facilitated by implicit memory for past visual experiences with those items. Several behavioral and neuroimaging studies suggest that this form of memory is dependent on perceptual processes localized in the right occipital lobe. We tested this claim by examining implicit memory in patients with extensive right occipital lobe lesions, using lexical-decision, mirror-reading, picture-fragment, and word-fragment-completion tests, and found that these patients exhibited normal levels of priming. We also examined implicit memory in patients with complete callosotomies, using standard and divided-visual-field word-fragment-completion procedures, and found that the isolated left hemisphere exhibited normal priming effects. The results indicate that the right occipital lobe does not play a necessary role in visual implicit memory, and that the isolated left hemisphere can support normal levels of visual priming in a variety of tasks.