An on-line task for contrasting auditory processing in the verbal and nonverbal domains and norms for younger and older adults

Contrasting linguistic and nonlinguistic processing has been of interest to many researchers with different scientific, theoretical, or clinical questions. However, previous work on this type of comparative analysis and experimentation has been limited. In particular, little is known about the differences and similarities between the perceptual, cognitive, and neural processing of nonverbal environmental sounds and that of speech sounds. With the aim of contrasting verbal and nonverbal processing in the auditory modality, we developed a new on-line measure that can be administered to subjects from different clinical, neurological, or sociocultural groups. This is an on-line task of sound to picture matching, in which the sounds are either environmental sounds or their linguistic equivalents and which is controlled for potential task and item confounds across the two sound types. Here, we describe the design and development of our measure and report norming data for healthy subjects from two different adult age groups: younger adults (18–24 years of age) and older adults (54–78 years of age). We also outline other populations to which the test has been or is being administered. In addition to the results reported here, the test can be useful to other researchers who are interested in systematically contrasting verbal and nonverbal auditory processing in other populations.     

Do age of onset and course of illness define biologically distinct groups within atypical depression?

Illness course separates patients with atypical depression into tricyclic responders and nonresponders as does perceptual asymmetry. The authors therefore investigated whether the course-of-illness parameters would define groups within atypical depression differing in brain laterality. Patients with atypical depression were assessed for illness course and brain laterality. Two patient groups were defined, 1 with onset prior to age 20 plus a very chronic course, and a 2nd group having later onset or less chronic illness. Patients reporting early onset of very chronic dysphoria showed significantly less right-ear (left-hemisphere) accuracy and also differed in characteristic perceptual asymmetry when compared to patients with later onset or less chronicity. Course of illness may usefully define more homogeneous depressive subgroups within atypical depression.     

The Relationship of Imperatives and Self-Efficacy to Indices of Social Anxiety

Seventy-three college students participated in a study to assess the role of self-efficacy and imperatives in social anxiety. The students were asked to speak in front of a small group of their peers and their anxiety and length of time talking were measured. Neither lower self-efficacy nor higher levels of imperative thinking at Baseline were correlated with higher levels of anxiety. The critical finding was that subjects who showed higher levels of imperative thinking at Baseline spoke for a significantly shorter period of time. This suggests that the participant's anxiety was moderated by the performance of an instrumental response, in this situation by choosing to limit the amount of time spent talking. The results suggest the centrality of imperative thinking in shaping behavior in the domain of social anxiety.     

Print Me an Organ? Ethical and Regulatory Issues Emerging from 3D Bioprinting in Medicine

Recent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then it focuses on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article (1) considers whether there is a limit as to what should be bioprinted in medicine; (2) examines key risks of significant harm associated with testing 3D bioprinting for humans; (3) investigates the clinical trial paradigm used to test 3D bioprinting; (4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability; (5) explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatments.     

The use of visual information in natural scenes

Despite the complexity and diversity of natural scenes, humans are very fast and accurate at identifying basic-level scene categories. In this paper we develop a new technique (based on Bubbles, Gosselin & Schyns, 2001a; Schyns, Bonnar, & Gosselin, 2002) to determine some of the information requirements of basic-level scene categorizations. Using 2400 scenes from an established scene database (Oliva & Torralba, 2001), the algorithm randomly samples the Fourier coefficients of the phase spectrum. Sampled Fourier coefficients retain their original phase while the phase of nonsampled coefficients is replaced with that of white noise. Observers categorized the stimuli into 8 basic-level categories. The location of the sampled Fourier coefficients leading to correct categorizations was recorded per trial. Statistical analyses revealed the major scales and orientations of the phase spectrum that observers used to distinguish scene categories.     

The relative efficiency of two tests as a function of ability level

A new formula is developed for the relative efficiency of two tests measuring the same trait. The formula expresses relative efficiency solely in terms of the standard errors of measurement and, surprisingly, the frequency distributions of true scores. Approximate methods for estimating relative efficiency may make this function routinely available. A numerical illustration compares new and old estimates of relative efficiency for subtests from the Scholastic Aptitude Test.Research reported in this paper has been supported by grant GB-32781X from National Science Foundation.     

The relation of primary mental abilities to activity preferences

The relations of abilities, as measured by Thurstone'sTests for Primary Mental Abilities, to activity preferences, as measured by Kuder'sPreference Record, are investigated for a population of 512 university freshmen. Ability profiles for contrasted groups on each preference scale reveal relatively slight overlapping between the two sets of measures, although the apparent trends are reasonable. The Pearson inter-correlation coefficients of all pairs of measures involved were determined. Implications of the findings in relation to theory and to educational and vocational guidance are indicated.