Differential neuronal responses to the self and others in the extrastriate body area and the fusiform body area

The extrastriate body area (EBA) and the fusiform body area (FBA) are selectively activated by viewing human bodies. However, the role of these functionally defined brain areas in self-other discrimination is still unresolved. Thirty-one females were presented with 16 pictures of their own body and another body in a bikini and with scrambled images while fMRI was performed. Moreover, standardized stimulus material was used in order to localize the EBA and FBA. Region-of-interest analysis showed an enhanced BOLD response to the self-images relative to the non-self-images in the right EBA and FBA. The right EBA and FBA are activated differently by viewing oneself and others and might thus play a role in visual self-other discrimination.     

Evidence of Common Timing Processes in the Control of Manual,Orofacial, and Speech Movements

Recent investigations of timing in motor control have been interpreted as support for the concept of brain modularity. According to this concept, the brain is organized into functional modules that contain mechanisms responsible for general processes. Keele and colleagues (Keele & Hawkins, 1982; Keele & Ivry, 1987; Keele, Ivry, & Pokorny, 1987; Keele, Pokorny, Corcos, & Ivry, 1985) demonstrated that the within-subject variability in cycle duration of repetitive movements is correlated across finger, forearm, and foot movements, providing evidence in support of a general timing module. The present study examines the notion of timing modularity of speech and nonspeech movements of the oral motor system as well as the manual motor system. Subjects produced repetitive movements with the finger, forearm, and jaw. In addition, a fourth task involved the repetition of a syllable. All tasks were to be produced with a 400-ms cycle duration; target duration was established with a pacing tone, which then was removed. For each task, the within-subject variability of the cycle duration was computed for the unpaced movements over 20 trials. Significant correlations were found between each pair of effectors and tasks. The present results provide evidence that common timing processes are involved not only in movements of the limbs, but also in speech and nonspeech movements of oral structures.     

Cognitive Development of Lead Exposed Children from Ages 6 to 15 Years: An Application of Growth Curve Analysis

The effect of lead exposure on cognitive growth patterns was assessed in a longitudinal study of 196 children. Performances on tests of verbal comprehension and perceptual organization (Vocabulary & Block Design, Wechsler Intelligence Scales for Children) were measured at ages 6.5, 11 and 15 years. Growth curve analyses revealed that the quadratic model best described the relationship between test scores and age. Children with higher lead levels, as measured at age 15 years, demonstrated lower verbal comprehension scores over time and greater decline in their rate of Vocabulary development at age 15 years, as compared to children with lower lead levels. Lead exposure was not significantly associated with growth in perceptual organization test scores. Socioeconomic status and maternal intelligence were statistically significantly associated with growth patterns for both test scores, independent of the effects of lead. The findings suggest that lead negatively impacts the developmental progression of specific cognitive skills from childhood through adolescence.     

Goal pursuit in young adulthood: The role of personality and motivation in goal appraisal trajectories across 6 years

The aim of this longitudinal study was to examine changes in the appraisals of personal goals during young adulthood, and to investigate personality and motivation as predictors of goal appraisals. Israeli young adults (N = 284, 46% female) were assessed four times during ages 23–29 and reported on their goal appraisals (goal investment, goal momentum and goal stress), personality (efficacy and self-criticism) and motivation (autonomous motivation, controlled motivation, amotivation). The results showed mean stability for goal investment and momentum, whereas goal stress declined. Efficacy predicted higher goal investment and momentum 6 years later, while self-criticism accounted for individual differences in goal stress. Autonomous motivation predicted higher goal investment and momentum, while amotivation related to higher goal stress.     

Tracking the speech signal – Time-locked MEG signals during perception of ultra-fast and moderately fast speech in blind and in sighted listeners

Blind people can learn to understand speech at ultra-high syllable rates (ca. 20 syllables/s), a capability associated with hemodynamic activation of the central-visual system. To further elucidate the neural mechanisms underlying this skill, magnetoencephalographic (MEG) measurements during listening to sentence utterances were cross-correlated with time courses derived from the speech signal (envelope, syllable onsets and pitch periodicity) to capture phase-locked MEG components (14 blind, 12 sighted subjects; speech rate = 8 or 16 syllables/s, pre-defined source regions: auditory and visual cortex, inferior frontal gyrus). Blind individuals showed stronger phase locking in auditory cortex than sighted controls, and right-hemisphere visual cortex activity correlated with syllable onsets in case of ultra-fast speech. Furthermore, inferior-frontal MEG components time-locked to pitch periodicity displayed opposite lateralization effects in sighted (towards right hemisphere) and blind subjects (left). Thus, ultra-fast speech comprehension in blind individuals appears associated with changes in early signal-related processing mechanisms both within and outside the central-auditory terrain.     

Personal construct theory and the argument against mental illness

An attempt is made to integrate Thomas Szasz's 0974) theory of personal conduct and George Kelly's (1955) theory of personal constructs (PCT). It is argued that PCT provides an alternative to the void left behind by Szasz's negation of mental illness. Because PCT is concerned with psychological, rather than physiological, constructions of problems in living, it is not compatible with the biological model associated with Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnostic categories. Rather, it is in keeping with the views of Szasz. Kelly's and Szasz's writings are used to support this view. Kelly's transitive diagnosis approach to “mental illness”, wherein diagnosis and therapy are construed as process oriented as opposed to category driven, is described as an alternative to the biological model. A contextualist approach (Sarbin & Mancuso, 1980) is also discussed. These approaches not only empower clients and allow them to assert responsibility and control over their lives, but also provide an alternative system to the one rejected by Szasz.