Effects of the Novel Acetylcholinesterase InhibitorN-Octyl-1,2,3,4-tetrahydro-9-aminoacridine on Locomotor Activity and Avoidance Learning in Mice

The acetylcholinesterase reversible inhibitorN-octyl-1,2,3,4-tetrahydro-9-aminoacridine (THA-C8) is a new synthesized derivative of tacrine (THA) characterized by an alkyl chain in the molecular structure which ameliorates the penetrability of the compound into the central nervous system. THA-C8 (0.1–5 mg/kg) significantly reduced spontaneous locomotor activity in CD1 mice at a dose of 3 mg/kg. Moreover, THA-C8 (0.2–2 mg/kg) significantly improved shuttle-box avoidance acquisition at doses (0.25, 0.3, 1 mg/kg) not affecting locomotion and that are much lower than the doses reported to be effective for THA in animal models. From the data reported it seems that the new compound could be interesting for therapeutic purposes.     

Figure-background segregation and the formation of illusory figures

Three experiments were carried out to test the relationship between figure-background segregation and illusory contours. Illusory figures are believed to arise as byproducts of figure-background segregation. When, in a scene, part of what should be the background becomes an illusory figure, a mechanism of contour attribution favoring the area in which the illusory figure appears takes place. This mechanism is prevented from operating when the attribution of the contour is inhibited by the presence of "groupable" (connectable) contours. Spatial proximity is one of the factors affecting such grouping: the closer the connectable contours, the more likely is their grouping in a single unit and the less likely is the emergence of an illusory figure. Experimental results showed that the illusory effect was established when contours were prevented from being connected. This outcome is interpreted as evidence that a mechanism of contour attribution is effective in the formation of illusory figures.     

Paradigms in Measure Theoretic Learning and in Informant Learning

We investigate many paradigms of identifications for classes of languages (namely: consistent learning, EX learning, learning with finitely many errors, behaviorally correct learning, and behaviorally correct learning with finitely many errors) in a measure-theoretic context, and we relate such paradigms to their analogues in learning on informants. Roughly speaking, the results say that most paradigms in measure-theoretic learning wrt some classes of distributions (called canonical) are equivalent to the corresponding paradigms for identification on informants.     

An Operational Logic of Proofs with Positive and Negative Information

The logic of proofs was introduced by Artemov in order to analize the formalization of the concept of proof rather than the concept of provability. In this context, some operations on proofs play a very important role. In this paper, we investigate some very natural operations, paying attention not only to positive information, but also to negative information (i.e. information saying that something cannot be a proof). We give a formalization for a fragment of such a logic of proofs, and we prove that our fragment is complete and decidable.     

A quantum theoretical explanation for probability judgment errors

A quantum probability model is introduced and used to explain human probability judgment errors including the conjunction and disjunction fallacies, averaging effects, unpacking effects, and order effects on inference. On the one hand, quantum theory is similar to other categorization and memory models of cognition in that it relies on vector spaces defined by features and similarities between vectors to determine probability judgments. On the other hand, quantum probability theory is a generalization of Bayesian probability theory because it is based on a set of (von Neumann) axioms that relax some of the classic (Kolmogorov) axioms. The quantum model is compared and contrasted with other competing explanations for these judgment errors, including the anchoring and adjustment model for probability judgments. In the quantum model, a new fundamental concept in cognition is advanced--the compatibility versus incompatibility of questions and the effect this can have on the sequential order of judgments. We conclude that quantum information-processing principles provide a viable and promising new way to understand human judgment and reasoning.     

The relation between overcommitment and burnout: does it depend on employee job satisfaction?

Using the Conservation of Resources (COR) theory as a framework, we hypothesized a maladaptive role played by overcommitment in the escalation of burnout. We further specified our model by testing an interaction effect of job satisfaction. By using a longitudinal design, we proposed a moderated mediational model in which burnout at Time 1 (T1) increases overcommitment, which in turn leads to more burnout one month later. We further expected to find a moderating role of job satisfaction in the link between overcommitment and burnout at Time 2 (T2). A group of 86 white-collar workers in personnel services in Italy (longitudinal response rate = 77.48%) participated in our study. The findings supported our hypotheses even when controlling for gender and role stressors. In particular, by using bootstrapping procedures to test mediation, we found evidence that employees reporting burnout tend to develop a maladaptive coping style, i.e., overcommitment, which in turn increases burnout over time. This relation was particularly strong for dissatisfied employees. These results highlight the importance of overcommitment for burnout escalation, as well as of job satisfaction, since it may mitigate, at least in the short term, the effect of such dysfunctional strategies.     

An Exploratory Model of Proximal Minority Stress and the Work–Life Interface for Men in Same‐Sex,Dual‐Earner Relationships

This study used a path analysis to test an exploratory model that analyzed associations among expectations of stigma, internalized homophobia, dyadic adjustment, and career development satisfaction. As part of the study, an online questionnaire was given to 170 men in same‐sex, dual‐earner relationships. Internalized homophobia and the expectation of stigma predicted ratings of dyadic adjustment, whereas only the expectation of stigma predicted ratings of career development satisfaction. Counseling implications, limitations, and directions for future research are discussed.     

Effect of a kickboxing match on salivary cortisol and immunoglobulin A

The hypothesis that salivary cortisol would increase and salivary immunoglobulin A (IgA) decrease after a kickboxing match was tested among 20 male athletes. Saliva samples collected before and after the match were analyzed. Salivary cortisol and salivary IgA concentrations (absolute concentration, salivary IgAabs) and the secretion rate of IgA (salivary IgArate) were measured by enzyme-linked immunosorbent assay. A Wilcoxon test for paired samples showed significant increases in salivary cortisol from pre- to postmatch. No significant changes were observed in salivary IgAabs or secretory IgArate and saliva flow rate. This study indicates that a kickboxing match might increase salivary concentration and thereafter it could be considered a significant source of exercise-related stress. On the other hand, the effect of a kickboxing match on mucosal immunity seems not to be relevant.     

On the Standard and Rational Completeness of some Axiomatic Extensions of the Monoidal T-norm Logic

The monoidal t-norm based logic MTL is obtained from Hájek's Basic Fuzzy logic BL by dropping the divisibility condition for the strong (or monoidal) conjunction. Recently, Jenei and Montgana have shown MTL to be standard complete, i.e. complete with respect to the class of residuated lattices in the real unit interval [0,1] defined by left-continuous t-norms and their residua. Its corresponding algebraic semantics is given by pre-linear residuated lattices. In this paper we address the issue of standard and rational completeness (rational completeness meaning completeness with respect to a class of algebras in the rational unit interval [0,1]) of some important axiomatic extensions of MTL corresponding to well-known parallel extensions of BL. Moreover, we investigate varieties of MTL algebras whose linearly ordered countable algebras embed into algebras whose lattice reduct is the real and/or the rational interval [0,1]. These embedding properties are used to investigate finite strong standard and/or rational completeness of the corresponding logics.