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141.
Franco Borgogno 《International Forum of Psychoanalysis》2016,25(4):214-219
AbstractReflecting in the present paper on the legitimacy of a work to collect together the ideas, concepts, and terms of Sándor Ferenczi, the author will explore, through a series of questions and answers, the following points: why it is so clear-cut that Ferenczi should be included in the company of those great psychoanalytic authors who might be deemed entitled to such a study; whether Ferenczi possessed his own language, and if this was the case, when and how he acquired it; what we mean when we refer to Ferenczi’s idiomatic language, and how we can profitably identify this language and bring it into focus; how, in practice, such a text should be organized; what its audience and function would be; and how it would be used by readers and students of Ferenczi. 相似文献
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Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain
Giménez-Llort L Schiffmann SN Shmidt T Canela L Camón L Wassholm M Canals M Terasmaa A Fernández-Teruel A Tobeña A Popova E Ferré S Agnati L Ciruela F Martínez E Scheel-Kruger J Lluis C Franco R Fuxe K Bader M 《Neurobiology of learning and memory》2007,87(1):42-56
Adenosine receptors in the central nervous system have been implicated in the modulation of different behavioural patterns and cognitive functions although the specific role of A(2A) receptor (A(2A)R) subtype in learning and memory is still unclear. In the present work we establish a novel transgenic rat strain, TGR(NSEhA2A), overexpressing adenosine A(2A)Rs mainly in the cerebral cortex, the hippocampal formation, and the cerebellum. Thereafter, we explore the relevance of this A(2A)Rs overexpression for learning and memory function. Animals were behaviourally assessed in several learning and memory tasks (6-arms radial tunnel maze, T-maze, object recognition, and several Morris water maze paradigms) and other tests for spontaneous motor activity (open field, hexagonal tunnel maze) and anxiety (plus maze) as modification of these behaviours may interfere with the assessment of cognitive function. Neither motor performance and emotional/anxious-like behaviours were altered by overexpression of A(2A)Rs. TGR(NSEhA2A) showed normal hippocampal-dependent learning of spatial reference memory. However, they presented working memory deficits as detected by performance of constant errors in the blind arms of the 6 arm radial tunnel maze, reduced recognition of a novel object and a lack of learning improvement over four trials on the same day which was not observed over consecutive days in a repeated acquisition paradigm in the Morris water maze. Given the interdependence between adenosinic and dopaminergic function, the present results render the novel TGR(NSEhA2A) as a putative animal model for the working memory deficits and cognitive disruptions related to overstimulation of cortical A(2A)Rs or to dopaminergic prefrontal dysfunction as seen in schizophrenic or Parkinson's disease patients. 相似文献
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Raffaele Antonelli Incalzi Andrea Corsonello Luigi Trojano Claudio Pedone Domenico Acanfora Aldo Spada Gianni D’Addio Roberto Maestri Franco Rengo Giuseppe Rengo 《Brain and cognition》2009
We studied 54 patients with hypoxemic chronic obstructive pulmonary disease (COPD). The Mini Mental State Examination and the Mental Deterioration Battery were used for neuropsychological assessment. Heart rate variability (HRV) was assessed based on 24-h Holter ECG recording. Mann–Whitney test was used to compare HRV parameters of patients performing normally or abnormally on individual neuropsychological tasks. Spearman’s rho was used to investigate the correlations between HRV parameters and neuropsychological scores, indexes of health status or COPD severity. Patients with defective performance at copying drawings with landmarks (CDL) test (N = 23) had lower very low frequency (VLF) power with respect to patients with normal performance (N = 31) (24 h: median 213; interquartile range 120–282 vs. 309; 188–431 ms2, p = 0.043; daytime: 202; 111–292 vs. 342; 194–397 ms2, p = 0.039). The CDL score correlated with the VLF power (24 h: ρ = 0.27, p = 0.049; daytime: ρ = 0.30, p = 0.028), and the normalized low frequency/high frequency (LF/HF) ratio (24 h: ρ = 0.27, p = 0.05; daytime: ρ = 0.33, p = 0.015). Sympathetic modulation decreased for increasing severity of COPD. In conclusion, drawing impairment correlates with depressed sympathetic modulation in patients with COPD, and both might be indexes of COPD severity. 相似文献
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We tested the idea that the correlation between implicit and explicit measures of prejudice depends on whether or not groups are normatively protected against discrimination. A pilot study (N=31) showed that 13 categories varied widely in the degree to which it is acceptable to express negative opinions about them. The main study involving 89 Catholic subjects found that explicit (reward allocation, liking ratings) and implicit measures (linguistic intergroup bias) of prejudice were correlated for the outgroup that is not normatively protected against discrimination (Islamic Fundamentalists) but uncorrelated for the outgroup that is protected (Jews). Copyright © 1999 John Wiley & Sons, Ltd. 相似文献
146.
Daisy M. Ellison 《Behavioral Interventions》1997,12(4):183-194
Compliance training was implemented to decrease non-compliance and avoidance behaviors in two women with severe mental retardation and psychiatric disorders over a five year period. In addition to compliance training, reinforcement schedules and behavioral momentum procedures were also included at various times. The program included training staff at home and at work to ensure generalization across settings and times, direct contact staff were used to assist in implementing compliance procedures at home and vocational trainers were used in the work setting. During baseline, Vanessa had pervasive non-compliant behaviors. Five years later, her non-compliance episodes had decreased by 89%. There were also significant decreases in aggression, self-abusive behaviors, and duration of non-compliance episodes. There were increases in interaction, productivity work, and reduced use of restraint. Annette was a woman with Generalized Anxiety Disorder with panic attacks. She had not left the home for several years. Once anxiety and panic attacks were under control maladaptive behaviors, which formerly functioned to avoid anxiety provoking situations, took on a different function, namely avoidance of work demands. Compliance training resulted in a reduction in non-compliance of 40–80% over a five year period. As a result psychoactive medication and restraint have been reduced and staff interaction and participation in campus and community activities have increased. © 1997 John Wiley & Sons, Ltd. 相似文献
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