Kv4 potassium channels modulate hippocampal EPSP-spike potentiation and spatial memory in rats

Kv4 channels regulate the backpropagation of action potentials (b-AP) and have been implicated in the modulation of long-term potentiation (LTP). Here we showed that blockade of Kv4 channels by the scorpion toxin AmmTX3 impaired reference memory in a radial maze task. In vivo, AmmTX3 intracerebroventricular (i.c.v.) infusion increased and stabilized the EPSP-spike (E-S) component of LTP in the dentate gyrus (DG), with no effect on basal transmission or short-term plasticity. This increase in E-S potentiation duration could result from the combination of an increase in excitability of DG granular cells with a reduction of GABAergic inhibition, leading to a strong reduction of input specificity. Radioactive in situ hybridization (ISH) was used to evaluate the amounts of Kv4.2 and Kv4.3 mRNA in brain structures at different stages of a spatial learning task in naive, pseudoconditioned, and conditioned rats. Significant differences in Kv4.2 and Kv4.3 mRNA levels were observed between conditioned and pseudoconditioned rats. Kv4.2 and Kv4.3 mRNA levels were transiently up-regulated in the striatum, nucleus accumbens, retrosplenial, and cingulate cortices during early stages of learning, suggesting an involvement in the switch from egocentric to allocentric strategies. Spatial learning performance was positively correlated with the levels of Kv4.2 and Kv4.3 mRNAs in several of these brain structures. Altogether our findings suggest that Kv4 channels could increase the signal-to-noise ratio during information acquisition, thereby allowing a better encoding of the memory trace.     

Validation d’une Échelle de Frustration des Besoins Psychologiques au Travail (EFBPT)

The purpose of the three present studies was to adapt in French in the work context a questionnaire developed by Bartholomew, Ntoumanis, Ryan, and Thøgersen- Ntoumani (2011) designed to assess thwarting of the needs for competence, autonomy, and relatedness. Exploratory (Study 1) and confirmatory analyses (Study were conducted among French workers. These studies demonstrated an acceptable internal consistency and confirmed the three-factor structure of the questionnaire (i.e., EFBPT). In addition, the construct validity of the scale was also corroborated in Study 3.     

L’accompagnement à la recherche d’un emploi : enjeux,modèles,et perspectives de recherche

What is at stake in the process of elaborating support to provide job seekers with personal advice, both theoretically and practically speaking? All through a review of papers, this article focuses on different theoretical schemes in the process of helping jobseekers to get back to work, but it also details the currently existing support devices and analyses their effects. Eventually it concentrates on the main psychological features taken into account in the process of counseling. As a conclusion, this article examines the perspectives and the consequences of molding and shaping personal counseling for jobseekers from a research angle.     

Enhanced embodied response following ambiguous emotional processing

It has generally been assumed that high-level cognitive and emotional processes are based on amodal conceptual information. In contrast, however, "embodied simulation" theory states that the perception of an emotional signal can trigger a simulation of the related state in the motor, somatosensory, and affective systems. To study the effect of social context on the mimicry effect predicted by the "embodied simulation" theory, we recorded the electromyographic (EMG) activity of participants when looking at emotional facial expressions. We observed an increase in embodied responses when the participants were exposed to a context involving social valence before seeing the emotional facial expressions. An examination of the dynamic EMG activity induced by two socially relevant emotional expressions (namely joy and anger) revealed enhanced EMG responses of the facial muscles associated with the related social prime (either positive or negative). These results are discussed within the general framework of embodiment theory.     

Enhanced embodied response following ambiguous emotional processing

It has generally been assumed that high-level cognitive and emotional processes are based on amodal conceptual information. In contrast, however, “embodied simulation” theory states that the perception of an emotional signal can trigger a simulation of the related state in the motor, somatosensory, and affective systems. To study the effect of social context on the mimicry effect predicted by the “embodied simulation” theory, we recorded the electromyographic (EMG) activity of participants when looking at emotional facial expressions. We observed an increase in embodied responses when the participants were exposed to a context involving social valence before seeing the emotional facial expressions. An examination of the dynamic EMG activity induced by two socially relevant emotional expressions (namely joy and anger) revealed enhanced EMG responses of the facial muscles associated with the related social prime (either positive or negative). These results are discussed within the general framework of embodiment theory.     

Evidence for the Syndrome of Nonverbal Learning Disabilities in Children with Brain Tumors

This study examined the predicted utility of the Nonverbal Learning Disabilities syndrome (NLD) (Rourke, 1995) for characterizing neurocognitive and psychosocial outcomes in 123 children with brain tumors. Children with brain tumors were found to be at high risk of having a specific academic deficit, particularly in arithmetic. Children with arithmetic deficit evidenced a higher rate of impairment on nonverbal tasks than on verbal tasks, whereas children with reading deficit evidenced a higher rate of impairment on verbal tasks than on nonverbal tasks. However, significant differences between children with arithmetic and reading deficits were not found for all of the component features of the NLD syndrome, and arithmetic deficit was not related to treatment with irradiation.     

The brain/body-in-the-world system is cognitive science’s study object for the twenty-first century / El sistema cerebro/cuerpo-en-el-mundo es el objeto de estudio de la ciencia cognitiva en el siglo XXI

Abstract

Modern cognitive science is the outcome of a transdisciplinary effort constituting the largest body of work about the mind in human history. These advancements have guided our understanding of the functional role of the agent’s body and context when producing adaptive behaviour and interactions. Thus, cognition is embodied, embedded, extended and enacted within inward- and outward-directed interactions, which is where the brain/body-in-the-world system emerges. We suggest that the goal of the new cognitive science is to understand the multi-level dynamic mechanisms underlying cognition-in-the-world and review the implications for the relationship between psychology and the social sciences.     

The role of athletes' pain-related anxiety in pain-related attentional processes

Numerous researchers have highlighted the social determinants of athletes' attitude toward pain, yet little is known about the role of cognitive processes and emotions that are related to pain in sport endeavors. There is evidence, in a dot probe paradigm, that individuals with chronic pain selectively orient their attention toward pain-related stimuli, but no studies have differentiated between the two attentional processes of hypervigilance that are evident in athletes: facilitated detection of threat and difficulty in disengaging attention from threatening stimuli. In the present study using a dot probe paradigm, we examined whether professional rugby players (N=58) with high pain-related anxiety (HPA) would show an attentional bias for pain-related threat, and whether this hypervigilance would reflect difficulty disengaging from threat or facilitated detection of threat. Rugby players with HPA oriented their attention toward pain-related threat with a concomitant difficulty disengaging from threat. Difficulty disengaging from painful stimuli may increase anxiety, and thus be maladaptive in sport. This is the first study to identify pain-related anxiety as a vulnerability marker in athletes' attentional biases.     

Jotting down notes or preparing for the future? Action identification and academic performance

The purpose of the present study was both to extend the performance optimality hypothesis of action identification theory to the realm of education and to examine the indirect role of action identification levels and action maintenance difficulty on the relationship between initial and final performance. Results demonstrated that students’ final performance is related to their initial performance and that this relationship is mediated by the way they identify the action of “attending a class”, which is itself inconsistently mediated by action maintenance difficulty. These findings pave the way for new educational applications in order to improve students’ academic performance.     

Semantic Hyperpriming in Normal Aging: A Consequence of Instructions?

Abstract

Semantic hyperpriming has consistently been found in normal aging. However, because the standard instructions to test semantic priming are generally ambiguous (focusing on both accuracy and speed), it is difficult to account for hyperpriming in older adults. By using the direct and mediated priming paradigms, this study investigates whether older adults' response mode at testing may explain hyperpriming. First, we show that, under identical conditions, inducing a response mode that favors speed leads to greater priming effects in older adults. The pattern of results is similar to what is observed under standard instructions. Second, prompting a response mode that favors accuracy leads to greater priming effects in younger adults. We discuss various explanations for these findings and conclude, in accordance with the Ratcliff, Thapar, Gomez, and McKoon (2004a Ratcliff, R., Thapar, A., Gomez, P. and McKoon, G. 2004a. A diffusion model analysis of the effects of aging in the lexical-decision task. Psychology and Aging, 19: 278–289. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) diffusion model, that hyperpriming in normal aging is contingent on older adults' response mode at testing.