HAROLD SEARLES: LIFELONG WORK OF A MASTER CLINICIAN

Harold F. Searles was one of the most gifted and innovative clinicians of psychoanalysis. His clinical work arouses interest on its own merit, as well as for the ways in which it shaped his highly innovative thinking. We can only imagine what special processes were developing in Searles’s inner world under the everlasting impact of his experience with psychotic patients and from his life in general. Searles focused extensively on how the psychotic individuals’ mental distortions impacted their capacity to form personal relationships in general, and the role of the analyst and countertransference in treatment. This unique viewpoint helped him sustain a creative commitment to psychotic patients, regarded by many as unsuitable for psychoanalysis.     

Motion as a Concept,an Insufficient Element in the Kantian Philosophy

Axiomathes - This article examines the Kantian ideas on motion in his work Metaphysical Foundations of Natural Science. In that essay, Kant holds that motion as a concept—from its connotation...     

Using Intergroup Contact Theory to Reduce Stigma Against Transgender Individuals: Impact of a Transgender Speaker Panel Presentation

Sexual minorities experience significant stigma and prejudice. Much research has examined sexual stigma and prejudice impacting gay and lesbian individuals, but limited research has examined other sexual minorities, such as transgender persons or individuals whose gender identity or expression is incongruent with their assigned gender or anatomical sex. Research has found that interpersonal contact with sexual minorities is associated with lower sexual stigma and prejudice. Intergroup contact theory predicts that interaction between groups can reduce stereotyping and improve intergroup relationships. Using a randomized crossover design, this study compared the impact of exposure to a transgender speaker panel vs. a traditional transgender lecture presentation on transphobia. Results indicated greater immediate reductions of transphobia following the transgender speaker panel than traditional lecture.     

An evaluation of progressively increasing intertrial intervals on the acquisition and generalization of three social skills

We evaluated the effects of different intertrial intervals (ITIs; time between programmed learning opportunities) on the acquisition and generalization of 2 preschoolers' social skills. Independent and generalized skills were observed only when the daily ITI was gradually increased from short to progressively longer intervals.     

Conflict Transformation, Stigma, and HIV-Preventive Structural Change

Over the prior decade, structural change efforts have become an important component of community-based HIV prevention initiatives. However, these efforts may not succeed when structural change initiatives encounter political resistance or invoke conflicting values, which may be likely when changes are intended to benefit a stigmatized population. The current study sought to examine the impact of target population stigma on the ability of 13 community coalitions to achieve structural change objectives. Results indicated that coalitions working on behalf of highly stigmatized populations had to abandon objectives more often than did coalitions working for less stigmatized populations because of external opposition to coalition objectives and resultant internal conflict over goals. Those coalitions that were most successful in meeting external challenges used opposition and conflict as transformative occasions by targeting conflicts directly and attempting to neutralize oppositional groups or turn them into strategic allies; less successful coalitions working on behalf of stigmatized groups struggled to determine an appropriate response to opposition. The role of conflict transformation as a success strategy for working on behalf of stigmatized groups is discussed.     

Dopamine modulation affects the performance of parkinsonian patients in a precision motor task measured by an antropomorphic device

Several parameters related to the timing, grip force and load force involved in a precision grasping task were studied in patients with Parkinson's disease (PD) at different moments of medication and healthy controls, using a sensorized anthropomorphic device which was totally adapted to the human hand. The aim of this work was to carry out an accurate study of the reach-load-grip-hold-place-release subtasks to identify any physical motor impairment, its relation to medication and Parkinsonian strategies. Twenty seven patients in ON and OFF-like medication moments, and twenty seven age-matched controls took part in the experiment, which consisted of using the index finger and the thumb to perform a precision motor task involving different experimental objects. Visual cues were used as distracting elements. Results showed several motor parameters impaired in OFF-like medication moment but attenuated in ON state, suggesting a medication effect on the performance of the task.     

Effects of (+) SKF 10,047, a sigma-1 receptor agonist, on anxiety,tested in two laboratory models in mice

Recently, sigma-1 receptor modulators have been considered drugs with an interesting therapeutic potential for the treatment of anxiety. However, there is no clear information in preclinical studies about the possible effects of sigma-1 ligands on anxiety in experimental animal models. Therefore, the present study examined the effects of (+)SKF 10,047 (2-8 mg/kg, ip), a sigma-1 agonist, on anxiety, tested in two classical laboratory models (social interaction test and elevated plus maze). (+)SKF 10,047 (8 mg/kg) produced a significant decrease of social investigation in the "social interaction test", whereas in the "elevated plus maze", the drug (4 and 8 mg/kg) provoked a significant reduction in the number of entries into open arms, as well as in the time spent in this area, as compared with the control group, without affecting motor activity. Overall, these findings indicate that (+)SKF 10,047 exhibits an anxiogenic-like profile in mice. It is suggested that anxiogenic effects of this sigma-1 ligand could be related to its potent ability to modulate diverse neurotransmitter systems involved in anxiety regulation.     

A latent variable approach to executive control in healthy ageing

It is a well-established finding that the central executive is fractionated in at least three separable component processes: Updating, Shifting, and Inhibition of information (Miyake et al., 2000). However, the fractionation of the central executive among the elderly has been less well explored, and Miyake's et al. latent structure has not yet been integrated with other models that propose additional components, such as access to long-term information. Here we administered a battery of classic and newer neuropsychological tests of executive functions to 122 healthy individuals aged between 48 and 91 years. The test scores were subjected to a latent variable analysis (LISREL), and yielded four factors. The factor structure obtained was broadly consistent with Miyake et al.'s three-factor model. However, an additional factor, which was labeled 'efficiency of access to long-term memory', and a mediator factor ('speed of processing') were apparent in our structural equation analysis. Furthermore, the best model that described executive functioning in our sample of healthy elderly adults included a two-factor solution, thus indicating a possible mechanism of dedifferentiation, which involves larger correlations and interdependence of latent variables as a consequence of cognitive ageing. These results are discussed in the light of current models of prefrontal cortex functioning.     

My Group's Fate Is My Fate: Identity-Fused Americans and Spaniards Link Personal Life Quality to Outcome of 2008 Elections

People differ in their reactions to the outcomes of their group. Whereas some may revel in victory and mourn in defeat, others may internalize victory but distance themselves from defeat. Here, we sought to relate these divergent reactions to two forms of alignment with groups–identity fusion and group identification. Investigations of the 2008 elections in the United States and Spain revealed that people who were “fused” with their political party internalized both victory and defeat, but highly identified persons internalized only victory. We discuss how these findings bear on the conceptual distinctions between identity fusion and group identification.