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121.
Research that uses simple response time tasks and neuroimaging has emphasized that attentional preparation based on temporal
expectancy modulates processing at motor levels. A novel approach was taken to study whether the temporal orienting of attention
can also modulate perceptual processing. A temporal-cuing paradigm was used together with a rapid serial visual presentation
procedure, in order to maximize the processing demands of perceptual analysis. Signal detection theory was applied in order
to examine whether temporal orienting affects processes related to perceptual sensitivity or to response criterion (indexed
byďand beta measures, respectively). If temporal orienting implies perceptual preparation, we would expect to observe an increase
in perceptual sensitivity (ď) when a target appeared at expected, rather than unexpected, time intervals. Indeed, our behavioral results opened the possibility
that focusing attention on time intervals not only enhances motor processing, as has been shown by previous research, but
also might improve perceptual processing. 相似文献
122.
Much previous research has demonstrated that visual search is typically disrupted by the presence of a unique “singleton”
distractor in the search display. Here we show that attentional capture by an irrelevant color singleton during shape search
critically depends on availability of working memory to the search task: When working memory is loaded in a concurrent yet
unrelated verbal short-term memory task, capture increases. These findings converge with previous demonstrations that increasing
working memory load results in greater distractor interference in Stroop-like tasks (de Fockert, Rees, Frith, & Lavie, 2001;
Lavie, Hirst, de Fockert, & Viding, 2004), which support the hypothesis that working memory provides goal-directed control
of visual selective attention allowing to minimize interference by goal-irrelevant distractors. 相似文献
123.
Cammarota M Bevilaqua LR Rossato JI Ramirez M Medina JH Izquierdo I 《Neurobiology of learning and memory》2005,84(1):25-32
Both the acquisition and the extinction of memories leave short- and long-term mnemonic traces. Here, we show that in male Wistar rats, the short-term memory for a step-down inhibitory avoidance task (IA) is resistant to extinction, and that its expression does not influence retrieval or extinction of long-term memory. It has been known for some time that short- and long-term inhibitory avoidance memory involve separate and parallel processes. Here we show that, instead, short-term extinction of IA long-term memory is the first step towards its long-term extinction, and that this link requires functional NMDA receptors and protein synthesis in the CA1 region of the dorsal hippocampus at the time of the first CS-no US presentation. 相似文献
124.
The aim of this study is to analyze how the length of time a patient spends in an Intensive Care Unit (ICU) affects close relatives, with regard to specific clinical variables of personality, family relationships and fear of death. The study group consisted of 57 relatives of seriously ill patients admitted to the ICU of "Virgen del Rocío" Rehabilitation and Trauma Hospital (Seville, Spain). The instruments applied were: a psychosocial questionnaire, clinical analysis questionnaire, family environment scale and fear of death scale. The relatives of patients admitted to ICU obtained higher scores in hypochondria, suicidal depression, agitation, anxious depression, guilt-resentment, paranoia, psychasthenia, psychological maladjustment and self-expression, and less in fear of their own death, as when compared to interviews with the same relatives 4 years later. The length of time a patient spent in the ICU influenced relatives in some clinical variables of personality, family relationships and fear of death 相似文献
125.
Twenty-four detoxified opiate addicts were randomized to an experimental group and a control group to evaluate efficacy of a group cue-exposure treatment to reduce or extinguish classically conditioned responses to drug-related stimuli. Assessment included psychophysiological responses (skin temperature, skin conductance level--SCL--, and heart rate) to a videotape and subjective measures (subjective craving, positive and negative affect) before and after the videotape. The experimental group received a group cue-exposure program to drug-related stimuli that comprised twelve treatment sessions administered three times weekly. The treatment program significantly reduced conditioned responses to drug-related stimuli, as measured by SCL and positive affect. 相似文献
126.
Spatial learning in rats is impaired by microinfusions of protein kinase C-gamma antisense oligodeoxynucleotide within the nucleus accumbens 总被引:1,自引:0,他引:1
Alvarez-Jaimes L Betancourt E Centeno-González M Feliciano-Rivera MZ Rodríguez D Peña de Ortíz S Maldonado-Vlaar CS 《Neurobiology of learning and memory》2004,81(2):120-136
The nucleus accumbens (NAcc) has been shown to play a role in motor and spatial learning. Protein kinase C (PKC) has been implicated in the mechanisms of initiation and maintenance of long-term potentiation that is thought to be involved in the storage of long-term memory. In the present study, the importance of de novo synthesis of PKC-gamma within the NAcc in the acquisition and retention of spatial discrimination learning was assessed using an antisense knockdown approach. Separate groups of Long-Evans rats were exposed to acute microinfusions (6microg/microl) of PKC-gamma antisense oligodeoxynucleotide (AS-ODN), control oligodeoxynucleotide (C-ODN) or vehicle into the NAcc at 24 and 3h before each training session. Behavioral findings showed that the blockade of NAcc-PKC-gamma translation caused impairments in the early phase of learning and retention of spatial information. Biochemical experiments showed that PKC-gamma expression was reduced and Ca(2+)/phospholipid-dependent protein kinase C (PKC) activity was blocked significantly in the AS-ODN-treated rats in comparison with control rats. The present findings suggest that NAcc-PKC-gamma plays a role during the early acquisition of spatial learning. Also, retention test results suggest that NAcc-PKC-gamma may be working as an intermediate factor involved in the onset of molecular mechanisms necessary for spatial memory consolidation within the NAcc. 相似文献
127.
The fact that early lexical and grammatical acquisition are strongly correlated has been cited as evidence against the view that the language faculty is composed of dissociable and autonomous modules (Bates & Goodman, 1997). However, previous studies have not yet eliminated the possibility that lexical-grammar associations may be attributable to language-general individual differences (e.g. children who are good at learning words are good at learning grammar). Parent report assessments of toddlers who are simultaneously learning English and Spanish (n = 113) allow an examination of the specificity of lexical-grammar relationships while holding child factors constant. Within-language vocabulary-grammar associations were stronger than cross-language relationships, even after controlling for age, proportion of language exposure, general language skill and reporter bias. Similar patterns were found based on naturalistic language samples (n = 22), ruling out a methodological artifact. These results are consistent with the view that grammar learning is specifically tied to lexical progress in a given language and provide further support for strong lexical-grammatical continuity early in acquisition. 相似文献
128.
Yago E Duarte A Wong T Barceló F Knight RT 《Cognitive, affective & behavioral neuroscience》2004,4(4):609-617
Single-unit, event-related potential (ERP), and neuroimaging studies have implicated the prefrontal cortex (PFC) in top-down
control of attention and working memory. We conducted an experiment in patients with unilateral PFC damage (n=8) to assess the temporal kinetics of PFC-extrastriate interactions during visual attention. Subjects alternated attention
between the left and the right hemifields in successive runs while they detected target stimuli embedded in streams of repetitive
task-irrelevant stimuli (standards). The design enabled us to examine tonic (spatial selection) and phasic (feature selection)
PFC-extrastriate interactions. PFC damage impaired performance in the visual field contralateral to lesions, as manifested
by both larger reaction times and error rates. Assessment of the extrastriate P1 ERP revealed that the PFC exerts a tonic
(spatial selection) excitatory input to the ipsilateral extrastriate cortex as early as 100 msec post stimulus delivery. The
PFC exerts a second phasic (feature selection) excitatory extrastriate modulation from 180 to 300 msec, as evidenced by reductions
in selection negativity after damage. Finally, reductions of the N2 ERP to target stimuli supports the notion that the PFC
exerts a third phasic (target selection) signal necessary for successful template matching during postselection analysis of
target features. The results provide electrophysiological evidence of three distinct tonic and phasic PFC inputs to the extrastriate
cortex in the initial few hundred milliseconds of stimulus processing. Damage to this network appears to underlie the pervasive
deficits in attention observed in patients with prefrontal lesions. 相似文献
129.
This study examined the dimensional structure of Templer's Death Anxiety Scale and Abdel-Khalek's Death Obsession Scale. The responses of 289 Spanish students to the Spanish forms of both scales were evaluated by means of a principal components analysis with varimax rotation. Three significant factors were identified: Death Obsession, Cognitive-Affective, and Death Anxiety. The distribution of the factor loadings for the items of both scales on Factors 1 and 3 supported the discriminant validity of the constructs specific to each of the scales, while Factor 2 showed a common component in both scales characterized by cognitive and affective aspects in relation to the idea of death. 相似文献
130.
Prey might assess that risk level estimated in the first encounter with a predator was fixed in subsequent responses, whereas prey using flexible behavior would track short-term changes in risk. The authors examined, in the field, refuge use of Iberian rock lizards (Lacerta monticola) after simulated predator attacks and tested (a) how risk was assessed when multiple sources of risk were present simultaneously, (b) how short-term changes in risk level of successive attacks affected refuge use, and (c) whether the interval between attacks was important, insofar as attacks were considered to be coming from the same or different predators. Results suggest that lizards have a flexible estimate of risk that is based on multiple sources and flexibly dependent on previous estimates. 相似文献