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51.
Timing is essential for rapid effects of corticosterone on synaptic potentiation in the mouse hippocampus 下载免费PDF全文
Stress facilitates memory formation, but only when the stressor is closely linked to the learning context. These effects are, at least in part, mediated by corticosteroid hormones. Here we demonstrate that corticosterone rapidly facilitates synaptic potentiation in the mouse hippocampal CA1 area when high levels of the hormone and high-frequency stimulation coincide in time, but not when corticosterone is given either before or after repetitive stimulation. This effect could not be blocked by antagonists of the mineralocorticoid receptor and glucocorticoid receptor (spironolactone and RU 38486, respectively). These data provide a biological substrate for the important behavioral observation that stress and corticosteroid hormones can facilitate learning and memory processes. 相似文献
52.
Palchykova S Winsky-Sommerer R Meerlo P Dürr R Tobler I 《Neurobiology of learning and memory》2006,85(3):263-271
Many studies in animals and humans suggest that sleep facilitates learning, memory consolidation, and retrieval. Moreover, sleep deprivation (SD) incurred after learning, impaired memory in humans, mice, rats, and hamsters. We investigated the importance of sleep and its timing in an object recognition task in OF1 mice subjected to 6h SD either immediately after the acquisition phase (0-6 SD) or 6h later (7-12 SD), and in corresponding undisturbed controls. Motor activity was continuously recorded with infrared sensors. All groups explored two familiar, previously encountered objects to a similar extent, both at the end of the acquisition phase and 24h later during the test phase, indicating intact familiarity detection. During the test phase 0-6 SD mice failed to discriminate between the single novel and the two familiar objects. In contrast, the 7-12 SD group and the two control groups explored the novel object significantly longer than the two familiar objects. Plasma corticosterone levels determined after SD did not differ from time-matched undisturbed controls, but were significantly below the level measured after learning alone. ACTH did not differ between the groups. Therefore, it is unlikely that stress contributed to the memory impairment. We conclude that the loss of sleep and the activities the mice engaged in during the SD, impaired recognition memory retrieval, when they occurred immediately after acquisition. The delayed SD enabled memory consolidation during the 6h when the mice were allowed to sleep, and had no detrimental effect on memory. Neither SD schedule impaired object familiarity processing, suggesting that only specific cognitive abilities were sensitive to the intervention. Sleep may either actively promote memory formation, or alternatively, sleep may provide optimal conditions of non-interference for consolidation. 相似文献
53.
What information is used for sorting pictures of complex stimuli into categories? We applied a reverse correlation method to reveal the visual features mediating categorization in humans and baboons. Two baboons and 6 humans were trained to sort, by species, pictures of human and baboon faces on which random visual noise was superimposed. On ambiguous probe trials, a human-baboon morph was presented, eliciting "human" responses on some trials and "baboon" responses on others. The difference between the noise patterns that induced the two responses made explicit the information mediating the classification. Unlike the humans, the baboons based their categorization on information that closely matched that used by a theoretical observer responding solely on the basis of the pixel similarities between the probe and training images. We show that the classification-image technique and principal components analysis provide a method to make explicit the differences in the information mediating categorization in humans and animals. 相似文献
54.
55.
Developmental dyscalculia (DD) is a pervasive difficulty affecting number processing and arithmetic. It is encountered in around 6% of school-aged children. While previous studies have mainly focused on general cognitive functions, the present paper aims to further investigate the hypothesis of a specific numerical deficit in dyscalculia. The performance of 10- and 11-year-old children with DD characterised by a weakness in arithmetic facts retrieval and age-matched control children was compared on various number comparison tasks. Participants were asked to compare a quantity presented in either a symbolic (Arabic numerals, number words, canonical dots patterns) or a nonsymbolic format (noncanonical dots patterns, and random sticks patterns) to the reference quantity 5. DD children showed a greater numerical distance effect than control children, irrespective of the number format. This favours a deficit in the specialised cognitive system underlying the processing of number magnitude in children with DD. Results are discussed in terms of access and representation deficit hypotheses. 相似文献
56.
Mariëlle Stel Jim Blascovich Cade McCall Jessanne Mastop Rick B. van Baaren Roos Vonk 《European journal of social psychology》2010,40(5):867-880
The sharing of bodily states elicits in mimicker and mimickee corresponding conceptualisations, which facilitates liking. There are many studies showing the relatedness of mimicry and liking. However, the mimicry‐liking link has not been investigated under conditions in which the mimickee is liked or disliked a priori. In two studies, we examined moderating effects of a priori liking on the mimicry‐liking link. Liking was measured via self‐report measures (Studies 1 and 2) and behavioural measures using a virtual environment technology (Study 2). Results showed that when participants intentionally mimicked a disliked person, liking for that person was not improved, whereas when participants mimicked a liked person, liking for that person increased. These effects were shown to be mediated by affiliation. These studies not only provided further evidence of a link between mimicry and liking, but also demonstrated that this relationship is moderated by a priori liking. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
57.
Juliette Gatto Michaël Dambrun Christian Kerbrat Pierre De Oliveira 《European journal of social psychology》2010,40(2):252-269
The principal aim of this study is to determine why police officers are generally found to be more prejudiced towards disadvantaged groups than are the standard population. Two independent processes were expected to account for this effect: Selection and group socialisation. Using a cross‐sectional design (N = 170), firstly, we compared, newly recruited police officers with a control population (selection effect), and secondly, police officers with 1 year of training with the newly recruited ones (group socialisation effect). Results reveal a significant effect of both selection and group socialisation, the two being underlined by distinct processes; right‐wing authoritarianism (RWA) in the case of the former and internalisation of a prejudice norm in the case of the latter. Finally, the results show that group identification moderates the change in internalisation of the prejudice norm. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
58.
Abstract The icosahedral quasicrystals i-AIMn, isomorphically substituted by 28 at.% Fe or by a mixture of (CrFe) atoms, have been studied for the first time by in-field Mössbauer spectroscopy in order to determine the sign and asymmetry parameter of the dominant electric-field gradient (EFG) term. In addition, the orthorhombic o-Al(MnFe) and cubic α- and hexagonal β-Al(MnFe)Si crystalline phases have been studied. We show that the previous Mössbauer results are inadequate for determining whether there are two sites in the quasicrystalline structure in the ratio of the golden number. Our results for i-Al(MnFe) show that the dominant EFG is negative, with an asymmetry parameter of about 0·6. For i-Al(CrFe), essentially no deviations are found from the model of Czjzek or the Gaussian isotropic model. One crystalline phase, the hexagonal β phase, is found to have a very similar quadrupole effect to that found in i-Al(MnFe). In addition it is found that this phase undergoes a change which is at least partly of magnetic origin. 相似文献
59.
Cyril Camachon David M. Jacobs Mickaël Huet Martinus Buekers Gilles Montagne 《Ecological Psychology》2013,25(4):367-382
Concurrent feedback is defined as information about performance given to participants during the execution of an action. This article investigates whether concurrent feedback is beneficial or detrimental to the learning of an ecologically relevant task. Eighteen participants were asked to walk through a virtual corridor and they practiced over 1110 trials to adjust their walking speed so as to pass through sliding doors that opened and closed at a frequency of 1 Hz. Concurrent feedback informed them about the possible need to accelerate or decelerate. Performance of participants who received concurrent feedback on 66% of the practice trials (on average) did not differ significantly from performance of participants who did not receive concurrent feedback. Furthermore, participants of both of these groups significantly outperformed participants who received concurrent feedback on all practice trials. These results are discussed in relation to the perceptual-motor mechanisms that underlie the control of the action. Also discussed are implications for future research, including the use of self-controlled feedback and the use of multisensory training programs. 相似文献
60.
Jaap H. van Dieën Huub M. Toussaint Cora Maurice Martine Mientjes 《Journal of motor behavior》2013,45(4):304-305
In this study, changes in movement coordination caused by fatigue that developed during repetitive lifting were examined. Five men performed 6 times a 5-min bout of lifting an 8-kg barbell at 15 lifts/min, using two lifting techniques; one minimized trunk rotation (squat lift), and the other minimized rotation in the knee joint (stoop lift). Kinematics and dynamics were studied by means of movement analysis and inverse dynamics, using a two-dimensional linked segment model. Within-subject variation over repetitive lifts of the time course of joint angles was smaller than between-subjects variation on the first analyzed lift. Relative timing between joint rotations did not change significantly across repetitive lifts, except between knee and hip in the squat lift. No change of the lumbosacral torque over repetitive lifts was found. The adaptability of the neural control appeared to be sufficient to accommodate the strong changes of the input-output characteristics of the muscles caused by fatigue so that an essentially constant performance of the movement act was maintained. 相似文献