Psychiatric Symptoms and Quality of Life in Patients Affected by Epidermolysis Bullosa

The aim of our study was to provide a psychosocial and psychiatric evaluation of patients with epidermolysis bullosa (EB; a rare genetic disorder characterized by skin fragility), to assess psychological status, ascertain the presence of any psychiatric disorders and understand the impact of EB on quality of life. Twenty-five patients were assessed using a case record form and several standardized instruments. In 82% of patients, EB had a negative impact on quality of life and 80% of patients experienced psychiatric symptoms. Our findings revealed a high prevalence of psychosocial problems and psychiatric symptoms in patients with EB and suggested that a combined bio-psychosocial approach is the most appropriate therapeutic intervention.     

Identity concept learning in matching-to-sample tasks by tufted capuchin monkeys (Cebus apella)

The abstract concept of equivalence is considered one of the bases of higher-order cognition, and it has been the subject of considerable research in comparative cognition. This study examined the conditions under which tufted capuchin monkeys (Cebus apella) are able to acquire an identity concept. Six capuchin monkeys were trained to solve a visual matching-to-sample (MTS) task on the basis of perceptual identity. The acquisition of the identity rule was inferred from the subject’s ability to solve transfer tests with novel stimuli. We evaluated the ability of the capuchin monkeys to match the shape of novel stimuli after training with both several small stimulus sets (Experiment 1) and a large stimulus set (Experiment 2). Moreover, we examined the ability of capuchins to transfer the concept to novel visual dimensions, such as colour and size and to transfer to novel spatial arrangements of the stimuli (Experiment 2). We demonstrated that the ability of capuchins to match novel stimuli was improved by increasing the number of stimuli used during training (Experiments 1 and 2) and that after a widely applicable identity concept based on the stimulus shape was acquired, the capuchins were able to match stimuli according to an identity rule based on both the colour and size of the stimuli and when the spatial arrangement of the stimuli was varied (Experiment 2). This study is the first to demonstrate that the size of the training set affects the acquisition of an abstract identity concept in an MTS task in non-human primates.     

Truth,Predication and a Family of Contingent Paradoxes

In truth theory one aims at general formal laws governing the attribution of truth to statements. Gupta’s and Belnap’s revision-theoretic approach provides various well-motivated theories of truth, in particular T* and T#, which tame the Liar and related paradoxes without a Tarskian hierarchy of languages. In property theory, one similarly aims at general formal laws governing the predication of properties. To avoid Russell’s paradox in this area a recourse to type theory is still popular, as testified by recent work in formal metaphysics by Williamson and Hale. There is a contingent Liar that has been taken to be a problem for type theory. But this is because this Liar has been presented without an explicit recourse to a truth predicate. Thus, type theory could avoid this paradox by incorporating such a predicate and accepting an appropriate theory of truth. There is however a contingent paradox of predication that more clearly undermines the viability of type theory. It is then suggested that a type-free property theory is a better option. One can pursue it, by generalizing the revision-theoretic approach to predication, as it has been done by Orilia with his system P*, based on T*. Although Gupta and Belnap do not explicitly declare a preference for T# over T*, they show that the latter has some advantages, such as the recovery of intuitively acceptable principles concerning truth and a better reconstruction of informal arguments involving this notion. A type-free system based on T# rather than T* extends these advantages to predication and thus fares better than P* in the intended applications of property theory.

     

Algebraic Analysis of Demodalised Analytic Implication

Journal of Philosophical Logic - The logic DAI of demodalised analytic implication has been introduced by J.M. Dunn (and independently investigated by R.D. Epstein) as a variation on a...     

Newborns are sensitive to multiple cues for word segmentation in continuous speech

Before infants can learn words, they must identify those words in continuous speech. Yet, the speech signal lacks obvious boundary markers, which poses a potential problem for language acquisition (Swingley, Philos Trans R Soc Lond. Series B, Biol Sci 364 (1536), 3617–3632, 2009). By the middle of the first year, infants seem to have solved this problem (Bergelson & Swingley, Proc Natl Acad Sci 109 (9), 3253–3258, 2012; Jusczyk & Aslin, Cogn Psychol 29 , 1–23, 1995), but it is unknown if segmentation abilities are present from birth, or if they only emerge after sufficient language exposure and/or brain maturation. Here, in two independent experiments, we looked at two cues known to be crucial for the segmentation of human speech: the computation of statistical co‐occurrences between syllables and the use of the language's prosody. After a brief familiarization of about 3 min with continuous speech, using functional near‐infrared spectroscopy, neonates showed differential brain responses on a recognition test to words that violated either the statistical (Experiment 1) or prosodic (Experiment 2) boundaries of the familiarization, compared to words that conformed to those boundaries. Importantly, word recognition in Experiment 2 occurred even in the absence of prosodic information at test, meaning that newborns encoded the phonological content independently of its prosody. These data indicate that humans are born with operational language processing and memory capacities and can use at least two types of cues to segment otherwise continuous speech, a key first step in language acquisition.     

Effects of group experiential cognitive therapy for the treatment of panic disorder with agoraphobia.

A treatment protocol, called experiential cognitive therapy (ExCT), was developed. It integrated traditional cognitive behavior therapy (CBT) with virtual reality exposure for the treatment of panic disorder with agoraphobia (PDA). The objective of this study was to test the efficacy of short-term (four sessions) ExCT compared with a traditional 12-session panic control program (PCP) for the treatment of PDA. Forty patients diagnosed as having PDA by the diagnostic criteria of DSM-IV were randomly assigned to ExCT and PCP groups of 20 patients each. The treatment effects were measured with self-report questionnaires, including the BDI, STAI, ASI, PBQ, ACQ, and BSQ. The authors also assessed high end-state functioning (HES), including the success rate of stopping or reducing medication at post-treatment and 6-month follow-up. In all ratings, both ExCT and PCP groups showed significant improvement post-treatment compared with pre-treatment scores. There were no significant differences between the two treatment groups in HES and medication discontinuation at post-treatment, but there was a significant difference in medication discontinuation at 6-month follow-up. These results suggested that although short-term effectiveness of ExCT might be comparable to the effectiveness of PCP, long-term effectiveness of ExCT might be relatively inferior to the effectiveness of PCP.     

The power of a story: New,automatic associations from a single reading of a short scenario

The implicit association test (IAT) is typically used to assess nonconscious categorization judgments that are “under control of automatically activated evaluation” (Greenwald, McGhee, & Schwartz, 1998, p. 1464) and that are usually considered independent of explicit judgments. The present study builds on recent work suggesting evidence of short-term modifiability of the IAT effect. Specifically, we show that reading a short text that describes a novel, fictional scenario, within which the to-be-evaluated categories are embedded, can produce substantial and immediate modulations of the IAT effect. This modulation effect does not occur when subjects are simply instructed to think about counterstereotypical associations (Experiment 1A and 1B). In Experiment 2, we use a variant of the IAT to show that scenario modulation cannot be explained in terms of strategic criterion shifts. These results suggest that a newly acquired knowledge structure targeting the abstract, category level can produce behavioral effects typically associated with automatic categorization.     

Manipulation of responsibility in non-clinical subjects: does expectation of failure exacerbate obsessive-compulsive behaviors?

An exaggerated sense of responsibility is currently considered as the ground for the obsessive-compulsive disorder. Obsessive-like behaviors, such as hesitations and checks, may be induced in non-clinical subjects by increasing perceived responsibility (i.e., perceived personal influence on negative outcomes). In line with Salkovskis' proposal [The cognitive approach to anxiety: threat beliefs, safety-seeking behavior, and the special case of health anxiety and obsessions, in: P.M. Salkovskis (Ed.), Frontiers of Cognitive Therapy, Guilford, New York], we tested the hypothesis that reduced coping abilities (i.e., an exaggerated expectation of failure) are another effectual factor contributing to obsessive-like behaviors. We examined 47 normal volunteers in a visuo-spatial memory task, and manipulated their perceived personal influence and expectation of failure by giving differential instructions and feedback about their performance. Increase of perceived personal influence induced slowness, hesitations and checks without enhancing performance. Expectation of failure exacerbated obsessive-like behaviors, again without affecting performance. These results confirm the role of responsibility in obsessive-like behavior and indicate that reduced coping abilities may contribute to worsen dysfunctional strategies.     

Differences in the perception and time course of syntactic and semantic violations

A reading time and an ERP experiment conducted in Italian investigated the parser's responses to a syntactic violation (subject-verb number agreement) and to a semantic violation (subject-verb selectional restriction), examining the time course of comprehension processes until sentence end. The reading-time data showed that the syntactic violation was detected earlier than the semantic one and that the two violations differed in the time-course. The ERP data fully supported the reading time data: Syntactic anomalies elicited a left anterior negativity (LAN) and a P600. Semantic anomalies elicited a N400 centred on the parietal sites which started 90 ms later (latency 430 ms) than the LAN. Furthermore, the N400 evoked by the words that followed the target word continued and increased until sentence end. The results are discussed with respect to the hypotheses that the parser constructs distinct syntactic and semantic analyses of a sentence and that this characteristic holds cross-linguistically. The appropriateness of different methodologies to the study of sentence processing is also evaluated.