A screening measure for BPD: the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD)

Borderline personality disorder (BPD) is a common psychiatric disorder that is often overlooked in treatment settings. This report describes the validation of a new self-report screening measure for DSM-IV BPD--the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD). Two hundred subjects with treatment histories whose ages ranged from 18 to 59 filled out the MSI-BPD. Each subject was then interviewed, blind to MSI-BPD results, with the BPD module of the Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV; Zanarini, Frankenburg, Sickel, & Yong, 1996). Of these 200 subjects, 139 (69.5%) met DSM-IV criteria for BPD as assessed by the BPD module of the DIPD-IV and the remaining 61 subjects (30.5%) did not. Using logistic regression analyses, an MSI-BPD cutoff of 7 or more of the measure's 10 items was judged to be the best cutoff. This was so because it yielded both good sensitivity (.81; percentage of correctly identified cases) and specificity (.85; percentage of correctly identified noncases) for the diagnosis of DSM-IV BPD. For younger subjects, diagnostic efficiency was even greater. For example, sensitivity was .90 and specificity was .93 at a cutoff of 7 for the 63 subjects who were 25 years old or younger. The results of this study suggest that the MSI-BPD may be a useful screening instrument for the presence of DSM-IV borderline personality disorder.     

Nonverbal estimation during numerosity judgements by adult humans

On an automated task, humans selected the larger of two sets of items, each created through the one-by-one addition of items. Participants repeated the alphabet out loud during trials so that they could not count the items. This manipulation disrupted counting without producing major effects on other cognitive capacities such as memory or attention, and performance of this experimental group was poorer than that of participants who counted the items. In Experiment 2, the size of individual items was varied, and performance remained stable when the larger numerical set contained a smaller total amount than the smaller numerical set (i.e., participants used numerical rather than nonnumerical quantity cues in making judgements). In Experiment 3, reports of the number of items in a single set showed scalar variability as accuracy decreased, and variability in responses increased with increases in true set size. These data indicate a mechanism for the approximate representation of numerosity in adult humans that might be shared with nonhuman animals.     

The McLean Study of Adult Development (MSAD): overview and implications of the first six years of prospective follow-up

The McLean Study of Adult Development (MSAD) began 12 years ago. It is the first NIMH-funded prospective study of the course and outcome of borderline personality disorder (BPD). After careful analysis of the first six years of follow-up, 5 main findings concerning the symptomatic and psychosocial course of BPD have emerged from this study. The first finding is that remissions are far more common than previously recognized (about 74%). The second is that these remissions are quite stable and thus, recurrences are quite rare (about 6%). The third finding is that completed suicides are far more rare than anticipated (about 4% vs. 10%). The fourth finding is that a "complex" model of borderline psychopathology best describes BPD. In this model, some symptoms resolve relatively quickly, are the best markers for the disorder, and are often the immediate reason for needing costly forms of treatment, such as psychiatric hospitalizations. We termed these symptoms (e.g., self-mutilation, help-seeking suicide threats or attempts) acute symptoms. Other symptoms resolve more slowly, are not specific to BPD, and are closely associated with ongoing psychosocial impairment. We termed such symptoms (e.g., chronic feelings of intense anger, profound abandonment concerns) temperamental symptoms. Fifth, it was also found that borderline patients were improving psychosocially over time, particularly remitted borderline patients; psychosocial functioning of remitted patients continued to improve as time progressed, suggesting that they were somewhat belatedly achieving the milestones of young adulthood and not simply returning to a prodromal level of functioning. Taken together, these results suggest that the prognosis for BPD is better than previously recognized.     

Modern prejudice toward gay men and lesbian women: assessing the viability of a measure of modern homonegative attitudes within an Irish context

The authors examined the psychometric properties of the gay and lesbian versions of the Modern Homonegativity Scale (MHS-G and MHS-L) in samples of heterosexual Irish university students (Ns=179 and 353). Confirmatory factor analyses revealed that the MHS-G and MHS-L were unidimensional and factorially distinct from a well-established measure of old-fashioned homonegativity (Attitudes Toward Lesbians and Gay Men Scale [ATLG]). Alpha coefficients for both versions of the MHS were good (range = .81 to .86), with 95% confidence intervals suggesting that unsatisfactory levels of scale score reliability (i.e., alpha values < .70) were relatively implausible. As hypothesized, participants' level of modern homonegativity correlated positively with their levels of old-fashioned and modem racism, patriotism, nationalism, religious fundamentalism, social dominance, and perceived political conservatism. The authors also observed a substantial inverse correlation between modern prejudice toward sexual minorities and support for their human rights. Finally, a series of multiple regression analyses indicated that, despite their interrelatedness, modern and old-fashioned homonegativity, particularly as they pertain to gay men, possess differential predictors. Limitations of the current series of studies and the need to conduct further research on attitudes toward sexual minorities within an Irish context are also discussed.     

Sources of exposure to smoking and drinking friends among adolescents: a behavioral-genetic evaluation

Substance-using friends expose adolescents to models of, and opportunities for, substance use that may lead to its initiation or reinforce existing use. Using genetically informative data from the National Longitudinal Study of Adolescent Health (P. S. Bearman, J. Jones, & J. R. Udry, 1998), the authors examined whether adolescents' exposure to friends' tobacco smoking and alcohol drinking was better explained by family-social or genetic influences. To conduct analyses, the authors constructed substance use exposure scores for adolescent siblings from the responses of siblings' nominated friends to self-reported smoking and drinking items. Using behavioral-genetic analyses of these substance use exposure scores, the authors estimated that 64% of the variance in adolescents' exposure to friends who smoke and drink could be explained by genetic influences, whereas shared environmental influences were zero. These results provide evidence of active, evocative, or both types of gene-environment correlations. Genetic factors can influence the formation of friendships with substance-using peers, thereby contributing to adolescents' exposure to substance use behaviors.     

Characterizing the motor execution stage of speech production: consonantal effects on delayed naming latency and onset duration

The research described in this article had 2 aims: to permit greater precision in the conduct of naming experiments and to contribute to a characterization of the motor execution stage of speech production. The authors report an exhaustive inventory of consonantal and postconsonantal influences on delayed naming latency and onset acoustic duration, derived from a hand-labeled corpus of single-syllable consonant-vowel utterances. Five talkers produced 6 repetitions each of a set of 168 prepared monosyllables, a set that comprised each of the consonantal onsets of English in 3 vowel contexts. Strong and significant effects associated with phonetic characteristics of initial and noninitial phonemes were observed on both delayed naming latency and onset acoustic duration. Results are discussed in terms of the biomechanical properties of the articulatory system that may give rise to these effects and in terms of their methodological implications for naming experiments.     

Switching between environmental representations in memory

In everyday life we accomplish tasks that require the storage and access of mental representations of different environments that we are not currently perceiving. Past research has suggested that environments are encoded by a series of independent representations that are organized in memory. Three experiments tested this idea further by asking whether multiple representations of environments can be accessed simultaneously. Using a cued task-set switching paradigm, subjects judged spatial relationships between target locations in two familiar environments. Response times were longer when successive trials probed different environments, an effect not due to switching between semantic categories or semantic priming, suggesting that representations of environments are accessed sequentially. Implications for various hypotheses concerning the properties of environmental representations are discussed.     

Where angels fear to tread: neurophenomenology and the matter of belief

The article explores Manuel Vásquez’ treatment of cultural neurophenomenology within the broader context of his non-reductionist methodology. By paying particular attention to the context of Tibetan Buddhist monks in disapora – the primary subjects of neurophenomenological research – it is suggested that Vásquez’ neurophenomenology is not as culturally mediated as he claims. His treatment may undermine his larger contention that politics shape both religious experience and the scholarly methodologies used to explore them.