Inhibitory processes and the control of memory retrieval

People are often confronted with reminders of things they would prefer not to think about. When this happens, they often attempt to put the unwanted memories out of awareness. Recent research shows that the capacity to suppress distracting traces is mediated by executive-control processes that are analogous to those involved in overriding prepotent motor responses, and it is these processes that cause persisting memory failures for the suppressed items. There is evidence that memory retrieval and motor tasks that are likely to demand executive control recruit overlapping neural mechanisms, suggesting that a common process mediates control in these domains. Together, these findings indicate that memory failures often arise from the mechanisms that lie at the heart of our capacity to influence the focus of thought.     

The topography of high-order human object areas

Cortical topography is one of the most fundamental organizing principles of cortical areas. One such topography - eccentricity mapping - is present even in high-order, ventral stream visual areas. Within these areas, different object categories have specific eccentricity biases. In particular, faces, letters and words appear to be associated with central visual-field bias, whereas buildings are associated with a peripheral one. We propose that resolution needs are an important factor in organizing object representations: objects whose recognition depends on analysis of fine detail will be associated with central-biased representations, whereas objects whose recognition entails large-scale integration will be more peripherally biased.     

Perception of correlated attributes involving African–American and white females' faces by 10‐month‐old infants

Thirty‐two 10‐month‐olds were habituated to stimuli containing an African–American female face or a white female face paired with a specific object. Test stimuli maintained or violated habituation stimuli pairings (i.e. categories). Results add to an emerging literature showing that 10‐month‐olds perceive categories of social information based on detection of correlated attributes. Copyright © 2003 John Wiley & Sons, Ltd.     

Parents of the Battered Child: A Multidisciplinary Group Therapy Approach to Life-Threatening Behavior

ABSTRACT: This paper reports the demographic findings and the experience of a three-year, multidisciplinary group psychotherapy program, with 31 child-abusing families. No predictive demographic characteristics were identified. The abuse of children ranged from mild bruising to severe brain damage and multiple fractures. Group therapy as an intervention procedure had its successes and failures. The dynamics of male-female co-therapists, the peer group sharing, and the capacity to ultimately verbalize inadequacies in the parenting role were crucial factors in therapy. As an experiential encounter the study gives a poignant insight into the personal and family pathology of parents who abuse their children.     

Perforant path activation modulates the induction of long-term potentiation of the schaffer collateral--hippocampal CA1 response: theoretical and experimental analyses

In one computational model of hippocampal function, the entorhinal cortical input to CA1 is hypothesized to play a key role in the ability of CA1 to decode CA3 recodings. Here, we develop a modification of this CA1 decoder hypothesis that is applicable to several computational theories of hippocampal function, and then we electrophysiologically investigate one assumption of this new hypothesis. First, using biologically realistic estimates, we calculate that CA3-induced CA1 excitation is too high and that inhibition plausibly plays a role in this CA1 decoder model. Thus motivated, we turn to a physiological demonstration to substantiate the plausibility of the proposed mechanism. Using the rat hippocampal slice, we examine an interlaminar interaction between the distal perforant path input to hippocampal CA1 stratum moleculare and the more proximal Schaffer collateral input to stratum radiatum. Perforant path activation provides sufficient inhibition to block homosynaptic long-term potentiation elicited by a suitably strong stratum radiatum input. For this interlaminar interaction to be most effective, perforant path activation must both precede and follow Schaffer collateral activation. Perforant path-evoked inhibition in CA1 can thus serve as a viable mechanism in the learned decoder theory of hippocampal CA1.