Peer-mediated reinforcement plus prompting as treatment for off-task behavior in children with attention deficit hyperactivity disorder

Functional analyses revealed that peer attention was one variable maintaining the off-task behavior exhibited by 3 students with a diagnosis of attention deficit hyperactivity disorder (ADHD). Peer-mediated reinforcement plus prompting was then used to reduce off-task behavior in a simulated classroom environment. Implications for future applications of this procedure with children diagnosed with ADHD are discussed.     

The effect of cholinergic, GABAergic, serotonergic, and glutamatergic receptor modulation on posttrial memory processing in the hippocampus

Though the hippocampus is widely recognized as important in learning and memory, most of the evidence for this comes from animal lesion and human pathological studies. Due to the relatively small number of drugs that have been tested in the hippocampus for their ability to alter posttrial memory processing, there is a general impression that memory processing involves only a few neurotransmitters. We have evaluated the effects of cholinergic, GABAergic, serotonergic, and glutamatergic receptor agonists and antagonists for their ability to facilitate or impair retention. CD-1 mice received acute intrahippocampal drug infusion following footshock avoidance training in a T-maze. Retention was tested 1 week after training and drug administration. The results indicate that receptor agonists of acetylcholine and glutamate improved retention, while antagonists impaired retention. However, scopolamine did not impair retention, but M1 and M2 antagonists did. Receptor agonists of serotonin and GABA impaired retention, while antagonists improved retention. Drugs acting on 5-HT-1 and 5-HT-2 as well as GABA(A) and GABA(B) receptor subtypes did not differentially effect retention.     

A Comparison of Multidimensional Health Profiles across Three Trauma-Exposed Diagnostic Groups

Posttraumatic stress disorder has been associated with adverse health outcomes. The extent to which the health effects of PTSD differ from other diagnoses has not been explored empirically. The current study investigated the Multidimensional Health Profile (including both Psychosocial and Health factors), across three diagnostic groups and one group of well-adjusted participants (N = 92) in a contrasted-groups design. Participants were all trauma-exposed and were assessed using structured clinical interviews. The PTSD and depression groups tended to differ from the social phobia and well-adjusted groups. Both the PTSD and depression groups demonstrated elevated profiles on variables assessing psychological distress, negative social exchange, and hypochondriasis. Results are consistent with prior research suggesting PTSD is associated with worse psychological and health functioning relative to trauma-exposed individuals without PTSD, although these health outcomes seem to differ little between those with PTSD and those with depression.     

Antibody to amyloid beta protein alleviates impaired acquisition,retention, and memory processing in SAMP8 mice

SAMP8 (senescence-accelerated mouse, P8 strain) mice overproduce amyloid precursor protein and beta-amyloid and have learning and memory deficits. Preliminary data have indicated that overproduction of beta-amyloid plays a role in the pathogenesis of acquisition and retention deficits in SAMP8 mice. In the studies reported here, the authors examined the effects of polyclonal and monoclonal antibodies to beta-amyloid on acquisition and retention in an aversive T-maze testing paradigm when injected intracerebroventricularly (ICV) into 12-month SAMP8/TaJF mice. Both the polyclonal and monoclonal antibodies improved acquisition and retention when injected ICV 1 to 14 days prior to acquisition testing. Injection of all three antibodies intrahippocampally immediately following training improved retention on the T-maze when mice were tested 7 days later. The authors next studied the effect of monoclonal beta-amyloid antibody injected 48 h prior to training on the effect on retention in the T-maze of drugs modulating classical neurotransmitters. Arecoline and glutamate were injected directly into the hippocampus, and ketanserin, methiothepen, bicuculline, and OH-saclofen were injected into the septum. Previously, the authors have found that the doses of these drugs required to improve retention are markedly altered in 12-month SAMP8/TkJF mice compared to 4-month P8 mice. In these studies, it was demonstrated that antibody to beta-amyloid resulted in these drugs improving retention at doses that improved memory in 4-month SAMP8/TaJF mice. Based on these findings, we conclude that beta-amyloid overproduction is at least in part responsible for the acquisition and memory deficits in 12-month-old SAMP8/TaJF mice. Antibody to beta-amyloid restores the retention response to neurotransmitter manipulation to that seen in 4-month-old mice. beta-amyloid appears to play a key role in the loss of acquisition and retention seen in SAMP8/TaJF mice.     

Cross‐national comparisons of attitudes towards suicide and suicidal persons in university students from 12 countries

This paper reports the results of a comparative investigation of attitudes to suicide and suicidal persons in 5,572 university students from 12 countries. Participants filled out two scales measuring attitudes towards suicide and suicidal persons, a measure of psychological distress together with the questions about suicidal behavior. Results showed that the highest suicide acceptance scores were observed in Austrian, UK, Japanese and Saudi Arabian samples and the lowest scores were noted in Tunisian, Turkish, Iranian and Palestinian samples. While the highest social acceptance scores for a suicidal friend were noted in Turkish, US, Italian and Tunisian samples, the lowest scores were seen in Japanese, Saudi Arabian, Palestinian and Jordanian samples. Compared to participants with a suicidal past, those who were never suicidal displayed more internal barriers against suicidal behavior. Men were more accepting of suicide than women but women were more willing to help an imagined suicidal peer. Participants with accepting attitudes towards suicide but rejecting attitudes towards suicidal persons reported more suicidal behavior and psychological distress, and were more often from high suicide rate countries and samples than their counterparts. They are considered to be caught in a fatal trap in which most predominant feelings of suicidality such as hopelessness or helplessness are likely to occur. We conclude that in some societies such as Japan and Saudi Arabia it might be difficult for suicidal individuals to activate and make use of social support systems.     

A computational procedure for the method of principal components

Ann-rowed correlation matrix may be thought of as an ellipsoid inn-dimensional space with its center at the origin. The principal components of the matrix are essentially the semi-axes of the ellipsoid. A direct and simple method of computing the lengths and directions of these semi-axes is presented.     

The interaction model of anxiety: An empirical test in an athletic competition situation

The person by situation interaction model of anxiety was tested in the field setting of a track and field meet. Forty-one male runners served as subjects. State anxiety was assessed just prior to a routine training session and again 2 weeks later just before a meet. Five facets of trait anxiety were measured after the routine training session. As predicted there was a significant interaction between social evaluation trait anxiety and the stressful meet situation. No interactions were observed for the interpersonal, ambiguous, and physical danger facets of trait anxiety. In general, the results supported the interaction model of anxiety.     

The political sacred and the holiness of life itself

ABSTRACT

This article reflects on Agamben’s formulation of the sacred within the political order of the West, contrasting this with the Durkheim/Bellah view of the sacred/profane opposition, and then presenting two arguments that reduction of the sacred to the political is insufficient, one a form of biological reductionism that seeks to locate the sacred within the common, biological nature of human life itself, the other an abductive argument for human transformation in terms of what Sloterdjik has called ‘vertical tension.’ This argument turns out to be one for locating holiness in the very notion of life itself that I wish to ground in the idea of social cognition.