Multi- and unisensory decoding of words and nonwords result in differential brain responses in dyslexic and nondyslexic adults

The present functional magnetic resonance imaging (fMRI) study was designed, in order to investigate the neural substrates involved in the audiovisual processing of disyllabic German words and pseudowords. Twelve dyslexic and 13 nondyslexic adults performed a lexical decision task while stimuli were presented unimodally (either aurally or visually) or bimodally (audiovisually simultaneously).The behavioral data collected during the experiment evidenced more accurate processing for bimodally than for unimodally presented stimuli irrespective of group. Words were processed faster than pseudowords. Notably, no group differences have been found for either accuracy or for reaction times. With respect to brain responses, nondyslexic compared to dyslexic adults elicited stronger hemodynamic responses in the leftward supramarginal gyrus (SMG), as well as in the right hemispheric superior temporal sulcus (STS). Furthermore, dyslexic compared to nondyslexic adults showed reduced responses to only aurally presented signals and enhanced hemodynamic responses to audiovisual, as well as visual stimulation in the right anterior insula.Our behavioral results evidence that the two groups easily identified the two-syllabic proper nouns that we provided them with. Our fMRI results indicate that dyslexics show less neuronal involvement of heteromodal and extrasylvian regions, namely, the STS, SMG, and insula when decoding phonological information. We posit that dyslexic adults evidence deficient functioning of word processing, which could possibly be attributed to deficits in phoneme to grapheme mapping. This problem may be caused by impaired audiovisual processing in multimodal areas.     

Proprioception plays a different role for sensorimotor adaptation to different distortions

If proprioceptive feedback is degraded by agonist-antagonist muscle vibration, then adaptation to rotated vision remains intact while adaptation to a velocity-dependent force field worsens. Here we evaluate whether this differential effect of vibration is related to the physical nature of the distortion - visual versus mechanical - or to their kinematic coupling to the subjects’ hand - velocity versus position dependent. Subjects adapted to a velocity-dependent visual distortion, to a position-dependent force, or to a velocity-dependent force; one half of the subjects adapted with, and the other half without agonist-antagonist vibration at the wrist, elbow, and shoulder. We found, as before, that vibration slowed down adaptation to a velocity-dependent force. However, vibration did not modify adaptation to the other two distortions, nor did it influence the aftereffects of any distortion. From this we conclude that intact proprioception supports strategic compensatory processes when proprioceptive signals agree with visual ones, and provide relevant (dynamic) information not available to the visual system.     

The role of anxiety and perspective-taking strategy on affective empathic responses

Empathy is an important pro-social behaviour critical to a positive client–therapist relationship. Therapist anxiety has been linked to reduced ability to empathise and lower client satisfaction with therapy. However, the nature of the relationship between anxiety and empathy is currently unclear. The current study investigated the effect of experimentally-induced anxiety on empathic responses elicited during three different perspective-taking tasks. Perspective-taking was manipulated within-subjects with all participants (N = 52) completing imagine-self, imagine-other and objective conditions. A threat of shock manipulation was used to vary anxiety between-subjects. Participants in the threat of shock condition reported higher levels of anxiety during the experiment and lower levels of empathy-related distress for the targets than participants in the control condition. Perspective-taking was associated with higher levels of empathy-related distress and concern compared to the objective condition. The present results suggest that perspective-taking can to a large extent mitigate the influence of heightened anxiety on an individual’s ability to empathise.     

The neurobiology of the stress-resistant brain

The 2010 Neurobiology of Stress Workshop brought together scientists from all over the world to share and discuss their results from studies examining the consequences of acute, repeated, and chronic stressor exposure on health and disease. Session IV entitled "The neurobiology of the stress-resistant brain" explored how we can intervene to promote stress resistance and stress resilience. Four scientists, who explore this topic from unique and convergent perspectives, presented their experimental results derived from studies in rat (Fleshner and Maier), non-human primates (Lyons), and human (Raskind). Summaries of each presentation, supporting publications, and overall take-home messages from the session are presented.     

Androstadienone in motor reactions of men and women toward angry faces

The endogenous compound androstadienone modulating the evaluation of others and activating the human fear system was hypothesized in terms of processing socially relevant cues by regulating responses to angry faces. Androstadienone was investigated in association with arm movements of 62 participants (30 women) in response to happy and angry facial expressions. Volunteers pushed away or pulled toward them a joystick as fast as possible on seeing either an angry or a happy cartoon face on a computer screen. This task was repeated twice: once during exposure to androstadienone masked with clove oil and once to clove oil only. In the former condition participants' reaction speed was accelerated, especially when reacting to angry faces. This observation may indicate an androstadienone-related activation of the fear system leading to faster responses to threat signals, assuming an enhanced allocation of attentional resources toward threat-related social cues.     

Association Learning with Own‐ and Other‐race Faces in three‐ and six‐month old infants – A longitudinal study

This longitudinal study assessed 133 Caucasian German infants at 3 and 6 months of age to investigate the influence of own‐race and other‐race faces as visual stimuli on association learning in the visual expectation paradigm (VExP). The study is related to the findings on the other‐race‐effect (ORE) which is said to emerge at 6 months of age. Caucasian faces were used as stimuli of a familiar ethnic category, whereas African faces were used as stimuli of an unfamiliar ethnic category. There was no significant difference between the two stimulus classes in infants' reaction time (RT) to stimulus shifts at 3 months. At 6 months of age, infants' RT decreased significantly in the Caucasian faces condition but not in the African faces condition. These results indicate that the processing of other‐race versus own‐race faces by the age of 6 months, which is also the relevant age for the onset of the ORE, has an important influence on the performance on the VExP. Copyright © 2011 John Wiley & Sons, Ltd.     

Infant Contingency Learning in Different Cultural Contexts

Three‐month‐old Cameroonian Nso farmer and German middle‐class infants were compared regarding learning and retention in a computerized mobile task. Infants achieving a preset learning criterion during reinforcement were tested for immediate and long‐term retention measured in terms of an increased response rate after reinforcement and after a 24‐h delay compared with baseline. It was hypothesized that infants from both cultural communities would acquire the contingency between own motion and mobile movement, as they similarly experience contingent responses in social interactions. Nso infants were assumed to show a higher learning rate related to their advanced gross motor development, whereas German infants were expected to show a higher baseline because of culture‐typical motor handling promoting a high level of activity (i.e. lying supine). Results showed immediate and long‐term retention in infants from both cultural contexts, as well as a higher baseline for German infants. Although the learning rate was higher for Cameroonian infants, logistic regression revealed that learning was not related to gross motor development but depended on the level of baseline response. Thus, contingency learning was shown in different cultural environments, and the level of baseline activity coined by culture‐specific motor handling turned out to influence learning within the mobile task. Copyright © 2012 John Wiley & Sons, Ltd.     

The effect of exercise and childbirth classes on fear of childbirth and locus of labor pain control

This study sought to track changes in intensity of fear of childbirth and locus of labor pain control in women attending an exercise program for pregnant women or traditional childbirth classes and to identify the predictors of these changes. The study was longitudinal/non-experimental in nature and run on 109 healthy primigravidae aged from 22 to 37, including 62 women participating in an exercise program for pregnant women and 47 women attending traditional childbirth classes. The following assessment tools were used: two scales developed by the present authors – the Fear of Childbirth Scale and the Control of Birth Pain Scale, three standardized psychological inventories for the big five personality traits (NEO Five Factors Inventory), trait anxiety (State–Trait Anxiety Inventory) and dispositional optimism (Life Oriented Test–Revised) and a questionnaire concerning socioeconomic status, health status, activities during pregnancy, relations with partners and expectations about childbirth. Fear of childbirth significantly decreased in women participating in the exercise program for pregnant women but not in women attending traditional childbirth classes. Several significant predictors of post-intervention fear of childbirth emerged: dispositional optimism and self-rated health (negative) and strength of the belief that childbirth pain depends on chance (positive).     

The Effect of High-Anxiety Situations on Conspiracy Thinking

The aim of the present studies was to examine a possible relationship between anxiety and conspiracy thinking about ethnic and national groups. Two hundred university student volunteers participated in 3 studies. Study One (N?=?87; mixed male and female sample) found that state-anxiety and trait-anxiety, measured with the Spielberger State-Trait Anxiety Inventory (STAI), were positively correlated with conspiracy thinking about Jewish people, Germans and Arabs. Study Two (N?=?46; male sample) and Study Three (N?=?67; female sample) were designed to check whether a high-anxiety situation (connected with waiting for an examination) would increase conspiracy thinking. Findings from Studies Two and Three showed that the pre-exam (high-anxiety) situation increased conspiracy thinking about Jewish people. This effect was not mediated by state-anxiety. Hence, further research should focus on searching for possible mediators of the relationship between a pre-exam situation and conspiracy thinking. The obtained results are consistent with previous findings showing that conspiracy thinking about Jewish people is sensitive to situational factors and with findings on links between anxiety and processing information about threat-related stimuli.