Effects of social isolation and environmental enrichment on atherosclerosis in ApoE-/- mice

Social support and a stimulating environment have been suggested to reduce stress reactions and cardiovascular risk. The aim of this study was to assess the role of environmental enrichment and social interaction for development of atherosclerosis in atherosclerosis prone mice. Male ApoE-/- mice were divided into four groups and followed during 20 weeks: (i) enriched environment (E, n=12), (ii) deprived environment (ED, n=12), (iii) enriched environment with exercise (E-Ex, n=12) and (iv) socially deprived by individual housing (SD, n=10). Plasma lipid and cytokine concentrations were measured. Atherosclerosis was quantified in cross-sections of innominate artery and en face in thoracic aorta. Plaque area was significantly increased in SD mice in the innominate artery (P<0.05 vs. all other groups), but not in the thoracic aorta. Plasma lipids were increased in SD mice (P<0.001 vs. all for total cholesterol, P<0.05 vs. E and P<0.01 vs. ED for triglycerides). Plasma concentration of granulocyte-colony stimulating factor (G-CSF) was decreased in SD mice compared to E mice (P<0.05). Thus, social isolation increased atherosclerosis and plasma lipids in ApoE-/- mice. Reduction in plasma G-CSF levels may hamper endothelial regeneration in the atherosclerotic process. While environmental enrichment did not affect atherosclerosis, social isolation accelerated atherosclerosis.     

Neurocognitive aspects of pain perception

The perception of pain is sensitive to various mental processes such as the feelings and beliefs that someone has about pain. It is therefore not exclusively driven by the noxious input. Attentional modulation involving the descending pain modulatory system has been examined extensively in neuroimaging studies. However, the investigation of neural mechanisms underlying more complex cognitive modulation is an emerging field in pain research. Recent findings indicate an engagement of the ventrolateral prefrontal cortex during more complex modulation, leading to a change or reappraisal of the emotional significance of pain. Taking placebo-induced analgesia as an example, we discuss the contribution of attention, expectation and reappraisal as three basic mechanisms that are important for the cognitive modulation of pain.     

Exploring noun bias in Filipino-English bilingual children

Researchers have suggested that there is a noun bias in children's early vocabularies brought about by features of adults' child-directed utterances, which may vary across languages (E. V. Bates et al., 1994; D. Gentner, 1982). In the present study, the authors explored noun bias in 60 Filipino-English bilingual children whose 2 languages differed in how they emphasized nouns and verbs in typical syntactic forms. The results revealed a noun bias, but only in the bilingual children's English vocabulary. The noun bias in English was associated with the frequency of nouns in the caregivers' utterances and the proportion of nouns in the initial positions of the caregivers' utterances. The authors also found different associations between salient positions in the adult utterances and children's vocabularies in English and Filipino.     

Emotional Intelligence of Foreign and Local University Students in Singapore: Implications for Managers

Does intelligence alone explain our achievement at work or in life? Contrary to our belief that academic achievement matters very much in the success we have in working life, Chen et al. (1998) has shown that close to 90% of success in leadership positions is attributable to Emotional Intelligence (EI). Considering that EI can be a potential determinant of our achievement in working life, this study aims to determine if there is any significant difference in the EI of local and foreign undergraduates studying in universities in Singapore. The “Emotional IQ Test” was administered to 100 undergraduates from various fields of studies from the National University of Singapore and Nanyang Technological University, of which 31 had foreign education background. This study showed that foreign undergraduates have a higher EI score than those with local education background. In addition, by examining the relationships between variables such as age, gender, year of study and EI, it was found that males have higher EI scores than that of females. The implication for managers is that staff should be evaluated on their own merits such as their EI rather than on academic results.     

Measuring Perceptions of Gender Roles: The IAWS for Pakistanis and U.S. Immigrant Populations

A new scale called the Islamic Attitudes Toward Women Scale (IAWS) was developed and administered to a sample of 195 Pakistani adults and to a sample of 140 Muslim immigrants in the United States. In support of the construct validation of the scale, it was found to significantly differentiate between liberal and conservative Muslims in Pakistan, and in both samples, men held more conservative attitudes than women. For both women and men, more liberal scores on the IAWS were correlated with less accepting beliefs about marital violence toward women. In the U.S. immigrant sample, those who had been in the United States longer had less conservative attitudes.     

Stress impairs acquisition of delay eyeblink conditioning in men and women

In rodents stress impairs delay as well as trace eyelid conditioning in females, but enhances it in males. The present study tested the effects of acute psychosocial stress exposure on classical delay eyeblink conditioning in healthy men and women. In a between subject design, participants were exposed to psychosocial stress using the Trier Social Stress Test (TSST) or a control condition which was followed by a delay eyeblink classical conditioning procedure. Stress exposure led to a significant increase in salivary cortisol and impaired acquisition of conditioned eyeblink responses (CRs). This was evident by a later first CR and an overall lower CR rate of the stress group. The stress-induced acquisition impairment was observed in both women and men. Subjects failing to show a stress-induced cortisol increase (cortisol non-responder) were not impaired in acquisition. Our findings indicate that acute stress, possibly via activation of the hypothalamus–pituitary–adrenal (HPA) axis, reduces the ability to acquire a simple conditioned motor response in humans.     

Nonstandard Work Arrangements among Women and Men Scientists and Engineers

This paper draws on a sample of 48,444 scientists and engineers in the United States to analyze nonstandard work arrangements among women and men, 8,773 of whom worked in such arrangements. With few exceptions, women were overrepresented in these arrangements and particularly in those characterized by lower wages and benefits, but their overrepresentation in the worst arrangements failed to explain the gender pay gap. Unlike in the general labor force where “equality at the bottom” tends to prevail, the gender pay gap in science and engineering is greater in the worst nonstandard work arrangements than in the best, and gender equality is greater in the best arrangements than in the worst, possibly because of a selection effect.     

Predicting black and white differential item functioning in verbal analogy performance

Differential item functioning (DIF) is one technique for comparing ethnic populations that test makers employ to help ensure the fairness of their tests. The purpose of this ethnic comparison study is to investigate factors that may have a significant influence on DIF values associated with 217 SAT and 234 GRE analogy items obtained by comparing large samples of Black and White examinees matched for total verbal score. In one study, five significant regression predictors of ethnic differences were found to account for approximately 30% of the DIF variance. A second study replicated these findings. These significant ethnic comparisons are interpreted as consistent with a cultural/contextualist framework although competing explanations involving social-economic status and biological contributions could not be ruled out. Practical implications are discussed.