Context effects in visual word recognition: Lexical relatedness and syntactic context

In three experiments, we investigated how associative word-word priming effects in German depend on different types of syntactic context in which the related words are embedded. The associative relation always concerned a verb as prime and a noun as target. Prime word and target word were embedded in visually presented strings of words that formed either a correct sentence, a scrambled list of words, or a sentence in which the target noun and the preceding definite article disagreed in syntactic gender. In contrast to previous studies (O’Seaghdha, 1989; Simpson, Peterson, Casteel, & Burgess, 1989), associative priming effects were not only obtained in correct sentences but also in scrambled word lists. Associative priming, however, was not obtained when the definite article and the target noun disagreed in syntactic gender. The latter finding suggests that a rather local violation of syntactic coherence reduces or eliminates word-word priming effects. The results are discussed in the context of related work on the effect of gender dis-/agreement between a syntactic context and a target noun.     

Analysis of sequence-dependent interactions between transient calcium and transmitter stimuli in activating adenylyl cyclase in Aplysia: possible contribution to CS--US sequence requirement during conditioning

An important recent insight in a number of neurobiological systems is that during learning, individual dually regulated proteins with associative properties function as critical sites of stimulus convergence. During conditioning in Aplysia, the Ca2+ /calmodulin-sensitive adenylyl cyclase (AC) in mechanosensory neurons serves as a molecular site of interaction between Ca2+ and serotonin [5-hydroxytryptamine (5-HT)]-two signals that represent the CS and US in these cells. Conditioning requires that the CS and US be paired within a narrow time window and in the appropriate sequence. AC shows an analogous sequence preference: It is more effectively activated when a pulse of Ca2+ precedes a pulse of 5-HT than when the 5-HT precedes Ca2+. One mechanism that contributes to this sequence preference is that Ca2+/calmodulin binding to AC accelerates the rate of AC activation by receptor-Gs. We have identified two additional properties of AC activation that would cause pairing with Ca2+ preceding 5-HT to be more effective than simultaneous pairing or pairing with the reciprocal sequence: (1) Activation of Aplysia AC by a Ca2+ pulse rose with a delay compared with activation by a 5-HT pulse. (2) A late pulse of Ca2+, which arrived after 5-HT, acted, via calmodulin, to accelerate the decay of AC activation by receptor-Gs. Together, these activation properties of AC may contribute to the CS-US sequence requirement of classical conditioning.     

Moral Responsibility and the Metaphysics of Free Will: Reply to van Inwagen

In The Philosophical Quarterly , 47 (1997), pp. 373–81, van Inwagen argues in a critical notice of my book The Metaphysics of Free Will that the impression that Frankfurt-type examples show that moral responsibility need not require alternative possibilities results from insufficient analytical precision. He suggests various precise principles which imply that moral responsibility requires alternative possibilities. In reply, I seek to defend the conclusion I have drawn from Frankfurt-type examples: moral responsibility need not require alternative possibilities. I contend that van Inwagen's principles — the principle of possible prevention and the no-matter-what principle — are invalid, and I suggest that their plausibility comes from thinking about a proper subset of the relevant cases.     

Illumination-induced apparent shift in orientation of human heads

Changing the position of a light source illuminating a human face induces an apparent shift of the perceived orientation of that face. The direction of this apparent shift is opposite to the shift of the light source. We demonstrated the illumination-induced apparent orientation shift (IAOS), quantified it in terms of the physical orientation shift needed to compensate for it, and evaluated the results in the context of possible mechanisms underlying orientation judgment. Results indicate that IAOS depends not only on the angle between the two light source positions, but also on the mean orientation of the face. Availability of cues coded in the visual texture of the face did not affect IAOS. The most effective cue was the location of the visible outline of the face. IAOS seems to be due to a shift of this outline when shadowed areas on the face merge with the black background. We conclude that an important mechanism for orientation judgment is based on a comparison of visible parts left and right of the profile line.     

Personality characteristics in primary benzodiazepine-dependent patients: Comparison with controls and polydrug users

The present study applied Karolinska Scales of Personality (KSP) to study (i) if patients with benzodiazepine dependence have a characteristic personality profile, (ii) if the personality characteristics in patients with benzodiazepine dependence differ from those of polydrug users and normal controls, (iii) if differences in treatment outcome existed between the groups, and (iv) if the possible difference in treatment outcome was associated with any particular personality characteristic shown by the patients. The personality characteristics of primary benzodiazepine dependent patients (BDZ) and a group of polydrug users (MIX) were studied initially (during the first week in project as an inpatient) and approximately one year after drug discontinuation, and a comparison was made with healthy controls on both test occasions. The results showed that the personality of both groups of patients differed significantly from the Controls in the following characteristics: Detachment, Socialization, Somatic Anxiety, Muscular Tension, Psychic Anxiety, and Psychasthenia. Significant differences existed between the polydrug and benzodiazepine users in Somatic and Psychic Anxiety as well as in Socialization. The MIX group differed significantly from the BDZ group and from the Controls in Suspicion. Results of treatment outcome indicated that the benzodiazepine dependent patients were significantly more successful in quitting their drug use compared to polydrug users. Further, the results demonstrated that patients scoring high in the investigated personality characteristics are those who fail the treatment goal of quitting their drug use, especially the patients with a high level of anxiety and detachment.