Olfaction in autism spectrum disorders: A systematic review

Olfactory function is a well-known early biomarker for neurodegeneration and neural functioning in the adult population, being supported by a number of brain structures that could be dysfunctioning in neurodegenerative processes. Evidence has suggested that atypical sensory and, particularly, olfactory processing is present in several neurodevelopmental conditions, including autism spectrum disorders (ASDs). In this paper, we present data obtained by a systematic literature review, conducted according to PRISMA guidelines, regarding the possible association between olfaction and ASDs, and analyze them critically in order to evaluate the occurrence of olfactory impairment in ASDs, as well as the possible usefulness of olfactory evaluation in such conditions. The results obtained in this analysis suggested a possible involvement of olfactory impairment in ASDs, underlining the importance of olfactory evaluation in the clinical assessment of ASDs. This assessment could be potentially included as a complementary evaluation in the diagnostic protocol of the condition. Methods for study selection and inclusion criteria were specified in advance and documented in PROSPERO protocol #CRD42014013939.     

How Transparent is Disgust?

According to the so‐called transparency thesis, what is disgusting in nature cannot but be disgusting in art. This paper critically discusses the arguments that have been put forward in favour of the transparency thesis, starting with Korsmeyer's ( 2011 ) sensory view of disgust. As an alternative, it offers an account of the relationship between disgust and representation that explains, at least in part, whatever truth there is in the transparency thesis. Such an account appeals to a distinction between object‐centric and situation‐centric emotions.     

Predication and cognitive context: Between minimalism and contextualism

In this paper, we suggest a strategy for modelling cognitive context within a truth‐conditional semantics, using Asher's model of predication. This allows us to introduce the notion of type presupposition intended as a lexical constraint to the composition of the truth‐conditional content. More specifically, we suggest that this model of predication produces a notion of truth‐conditional meaning where the cognitive context fixes a set of lexical restrictions and forced modifications. We conclude that this model might offer an intermediate position between Minimalism and Contextualism: an account that provides intuitive truth conditions within a formal semantic theory.     

Italian developmental dyslexic and proficient readers: where are the differences?

Italian dyslexic children are characterized by a pervasive reading speed deficit, with relatively preserved accuracy. This pattern has been associated with predominant use of the nonlexical reading procedure. However, there is no evidence of a deficit in the lexical route of Italian dyslexics. We investigated both lexical and nonlexical reading procedures in dyslexic children through two marker effects, namely, the word frequency effect and the effect of contextual grapheme-to-phoneme conversion rules. Although dyslexics were slower and less accurate than controls, they were affected by word frequency, grapheme contextuality, and their interaction in a similar manner as average readers. These results show the use of lexical reading in Italian dyslexics, and refute the claim of a deficit in whole-word processing with consequent over-reliance on the nonlexical route.     

A comparison of higher order auditory processes in younger and older adults

The authors conducted 3 experiments investigating the effects of aging on higher order auditory processes. They compared younger and older adults with respect to (a) their auditory channel capacity, (b) the extent of their top-down control over auditory gain, and (c) their ability to focus attention on a narrow band of frequencies. To ensure that subclinical cochlear processing deficits in older adults (e.g., higher thresholds, poorer discrimination of frequency and intensity differences) did not limit performance, the authors used only stimuli that were perfectly discriminable by all participants. No age differences were found in any of these experiments, suggesting that some higher order auditory processes (e.g., top-down control over auditory gain, auditory attention) are preserved in normal aging, despite numerous age-related declines in peripheral auditory functionality.     

Word length effect in early reading and in developmental dyslexia

Vocal reaction times were measured in Italian dyslexics and in proficient readers while they read single words. Three groups of control participants (for a total of 79) were tested. All were in the first, second or third grade of elementary school. Nine third graders with a low level of reading ability when assessed by standard reading procedures were also tested. Results indicated that vocal RTs of control participants were faster and less sensitive to word length as a function of age; also, there was a particularly marked change between first and second graders. Dyslexics' vocal RTs and errors were much worse than those of peer control participants and resembled those of first grade controls. It is suggested that normal readers in an orthographically transparent language (Italian) adopt a lexical strategy quite early in their learning. On the contrary, dyslexics seem unable to learn this mode of processing and continue to use a sub-lexical reading procedure.     

Separating global and specific factors in developmental dyslexia

The general goal of the study was to identify global and specific components in developmental dyslexia using various manipulations based on the rapid automatization paradigm (RAN). In two experiments, we used both factor analysis and the Rate-and-Amount Model to verify if one (or more) global factor(s) and a variety of specific effects contribute to the naming (and visual search) deficits in children with dyslexia.

Results of Experiment 1 indicated the presence of three global components: pictorial naming, detailed orthographic analysis, and visual search. Pictorial naming is predicated by typical RAN tasks (such as naming colors or objects), independent of set size, but also from a variety of other tasks including Stroop interference conditions. The detailed orthographic analysis factor accounts for naming of orthographic stimuli at high set size. Visual search marked tasks requiring the scanning of visual targets.

Results of Experiment 2 confirmed the separation between the pictorial naming and detailed orthographic analysis factors both in the original sample and in a new group of children. Furthermore, specific effects of frequency, lexicality, and length were shown to contribute to the reading deficit.

Overall, it is proposed that focusing on the profile of both global and specific effects provides a more effective and, at the same time, simpler account of the dyslexics' impairment.     

Separating global and specific factors in developmental dyslexia

The general goal of the study was to identify global and specific components in developmental dyslexia using various manipulations based on the rapid automatization paradigm (RAN). In two experiments, we used both factor analysis and the Rate-and-Amount Model to verify if one (or more) global factor(s) and a variety of specific effects contribute to the naming (and visual search) deficits in children with dyslexia. Results of Experiment 1 indicated the presence of three global components: pictorial naming, detailed orthographic analysis, and visual search. Pictorial naming is predicated by typical RAN tasks (such as naming colors or objects), independent of set size, but also from a variety of other tasks including Stroop interference conditions. The detailed orthographic analysis factor accounts for naming of orthographic stimuli at high set size. Visual search marked tasks requiring the scanning of visual targets. Results of Experiment 2 confirmed the separation between the pictorial naming and detailed orthographic analysis factors both in the original sample and in a new group of children. Furthermore, specific effects of frequency, lexicality, and length were shown to contribute to the reading deficit. Overall, it is proposed that focusing on the profile of both global and specific effects provides a more effective and, at the same time, simpler account of the dyslexics' impairment.     

At the borders of the average man: Adolphe Quêtelet on mental,moral, and criminal monstrosities

This study examines Adolphe Quêtelet's conception of deviance. It investigates how he identified social marginalities and what actions he recommended governments to undertake. To get a close understanding of his views, this paper examines three cases of “monstrosities,” namely mental alienation, drunkenness, and criminality. My main thesis is that Quêtelet provided scientific authority to a conception of deviance as sickness, immorality, and cost thus encouraging legislators to use statistics for containing social marginalities. The case of alienation shows that Quêtelet viewed insanity as a pathology of civilization to be understood through phrenology. The case of drunkenness demonstrates how Quêtelet conflated the notion of statistical mean with moral decency. The case of criminality illustrates Quêtelet's major concern with the cost of criminals for the state. While advocating for the perfectibility of mankind, Quêtelet urged governments to take actions against what he considered the monstrosities of society.