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221.
Discourse production was investigated in 16 patients with left-temporal-lobe epilepsy (LTLE) and 17 neurologically normal relatives. Narrative was elicited with the Joanette and Goulet (1989) eight frame "Cowboy" cartoon on three immediately consecutive occasions. Variables of interest were fluency (words/s), speaking time, and word count. While controls produced increasingly concise forms of the story over repetitions, the TLE group became more verbose. Fluency did not not differentiate the groups. These findings suggest that LTLE is associated with macrolinguistic disturbances. The role of capacity limitations and motivational factors in TLE discourse production is discussed. 相似文献
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Tessa Field Stephanie Jo Brewster Meghan Towne MaryAnn W. Campion 《Journal of genetic counseling》2016,25(4):708-719
Traditionally, the biotechnology and pharmaceutical industry (BPI) has focused drug development at the mass-market level targeting common medical issues. However, a recent trend is the development of therapies for orphan or rare disorders, including many genetic disorders. Developing treatments for genetic disorders requires an understanding of the needs of the community and translating genomic information to clinical and non-clinical audiences. The core skills of genetic counselors (GCs) include a deep knowledge of genetics and ability to communicate complex information to a broad audience, making GCs a choice fit for this shift in drug development. To date there is limited data defining the roles GCs hold within this industry. This exploratory study aimed to define the roles and motivation of GCs working in BPI, assess job satisfaction, and identify translatable skills and current gaps in GC training programs. The authors surveyed 26 GCs working in BPI in the United States; 79 % work for companies focused on rare disorders. GC positions in BPI are growing, with 57 % of respondents being the first GC in their role. GCs in BPI continue to utilize core genetic counseling competencies, though 72 % felt their training did not fully prepare them for BPI. These data suggest opportunities for exposure to BPI in GC training to better prepare future generations of GCs for these career opportunities. GC satisfaction was high in BPI, notably in areas traditionally reported as less satisfying on the National Society for Genetic Counselors Professional Status Survey: salary and advancement opportunities. BPI’s growing interest in rare disorders represents a career opportunity for GCs, addressing both historic areas of dissatisfaction for GCs and BPI’s genomic communication needs. 相似文献
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VL Hannig MP Cohen JP Pfotenhauer MD Williams TM Morgan JA Phillips III 《Journal of genetic counseling》2014,23(1):64-71
We established a general genetic counseling clinic (GCC) to help reduce long wait times for new patient appointments and to enhance services for a subset of patients. Genetic counselors, who are licensed in Tennessee, were the primary providers and MD geneticists served as medical advisors. This article describes the clinic referral sources, reasons for referral and patient dispositions following their GCC visit(s). We obtained patients by triaging referrals made to our medical genetics division. Over 24 months, our GCC provided timely visits for 321 patients, allowing the MD geneticists to focus on patients needing a clinical exam and/or complex medical management. Following their GCC visit(s), over 80 % of patients did not need additional appointments with an MD geneticist. The GCC allowed the genetic counselor to spend more time with patients than is possible in our traditional medical genetics clinic. Patient satisfaction surveys (n?=?30) were very positive overall concerning the care provided. Added benefits for the genetic counselors were increased professional responsibility, autonomy and visibility as health care providers. We conclude that genetic counselors are accepted as health care providers by patients and referring providers for a subset of clinical genetics cases. A GCC can expand genetic services, complement more traditional genetic clinic models and utilize the strengths of the genetic counselor health care provider. 相似文献
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The paper tries to spell out a connection between deductive logic and rationality, against Harman's arguments that there is no such connection, and also against the thought that any such connection would preclude rational change in logic. One might not need to connect logic to rationality if one could view logic as the science of what preserves truth by a certain kind of necessity (or by necessity plus logical form); but the paper points out a serious obstacle to any such view. 相似文献
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This review explores the literacy difficulties experienced by prelingual, profoundly deaf, sign-dominant adults. A critical overview of the existing literature identifies the importance of understanding their language experiences and word-coding preferences. Findings challenge the notion that a permanent lack of audition from birth prevents individuals from developing efficient strategies for the lexical processing of words and raises the possibility that sign-based word coding could play a central role in proficient word reading for those adults who cannot learn to read by way of the auditory perceptual route. The unique resources needed to assist in the development of the literacy skills of this minority group are discussed. 相似文献
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This study investigated differences in the phonological knowledge and reading skill of deaf adults using three experimental conditions that tested sensitivity to syllables, rhyme, and phonemes. Analysis of response latencies and accuracy in the three awareness tasks demonstrated that skilled deaf readers had superior phonological awareness skill to that of less-skilled readers and showed less reliance on orthography when making their phonological judgments. Rhyme had greater independent predictive strength than syllable or phoneme awareness for reading comprehension. Phoneme awareness did not contribute independently to either reading comprehension or word reading, but it did independently predict application of grapheme-phoneme correspondences. 相似文献
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