Differential activity profile of cAMP-dependent protein kinase isoforms during long-term memory consolidation in the crab Chasmagnathus

The isoforms of cAMP-dependent protein kinase (PKA) show distinct biochemical properties and subcellular localization, suggesting different physiological functions, and conferring the fine-tuning between the activation of cAMP-PKA cascade and the cellular response. The critical role of PKA in memory and synaptic plasticity has been extensively demonstrated both in vertebrates and invertebrates, but the role of PKA isoforms is a matter of debate. Here we present experimental data showing differential PKA activation profiles after two different experiences: an instance of associative contextual learning (context-signal learning) and a single exposure to a novel context, both in the learning and memory model of the crab Chasmagnathus. Differences were found in the temporal course of activation and in the involvement of PKA isoforms. We found increased PKA activity immediately and 6 h after context-signal training correlating with the critical periods during which pharmacological inhibition of PKA disrupts memory formation. In contrast, PKA activity increased immediately but not 6 h after single exposure to a novel context. The amounts of PKA I and PKA II holoenzymes were analyzed to determine changes in holoenzyme levels and/or differential activation induced by both experiences. Results indicate that context-induced PKA activation is at least in part due to PKA II, and that PKA activation 6 h after context-signal learning coincides with an increase in the total level of PKA I. Considering the higher sensitivity of PKA I to cAMP, its increment can account for the PKA activation found 6 h after training and is proposed as a novel mechanism providing the prolonged PKA activation during memory consolidation.     

Vocal learning in birds and humans

Vocal learning is the modification of vocal output by reference to auditory information. It allows for the imitation and improvisation of sounds that otherwise would not occur. The emergence of this skill may have been a primary step in the evolution of human language, but vocal learning is not unique to humans. It also occurs in songbirds, where its biology can be studied with greater ease. What follows is a review of some of the salient anatomical, developmental, and behavioral features of vocal learning, alongside parallels and differences between vocal learning in songbirds and humans.     

Psychometric appraisal of Eysenck's revised Psychoticism scale: a cross-cultural study

Psychometric characteristics of Eysenck's revised P scale were studied in a cross-cultural research. The Spanish version of the Eysenck Personality Questionnaire-Revised (EPQ-R) was administered to a Spanish sample of 527 males and 583 females. Maximum-likelihood factor analyses of the item intercorrelations and Direct Oblimin rotations of the extracted factors were carried out separately for males and females. The results revealed four factors identified as psychoticism (P), extraversion (E), neuroticism (N) and dissimulation/conformity (L). Internal consistency and test–retest reliability coefficients were satisfactory and very similar to the ones found in the original study. Skewness and kurtosis of the P scale distribution were closer to normal than on the original British revised P scale.     

Simulations of schedule-controlled behavior

A computer model that simulates the patterns of responding of infrahuman subjects under several schedules of reinforcement is described. The model is dynamic in that it continuously assesses the values of several interacting variables that are, in turn, affected by simulated environ-mental events that are scheduled by a procedure program. The data generated by the computer model, including cumulative records, closely conform to reported experimental data. The results indicate that computer simulations are a very useful tool for developing quantitative theories of operant behavior.     

The identity impact of witnessing selective incivility: A study of minority ethnic professionals

We examine how minority ethnic employees account for witnessing selective incivility to ethnically similar others. Our study is based on qualitative interviews with British Asian employees – the majority who witnessed incivility directed towards migrant Asian employees working for the same company. Our findings indicate that, for those whose minority ethnic identity was of central importance, witnessing selective incivility towards others from a similar ethnic background can be perceived as an identity threat. We provide insights into three identity work strategies undertaken by witnesses of selective incivility, while illuminating how minority ethnic identity shapes the way witnesses' respond to selective incivility in the workplace.     

Reasonable expectations,moral responsibility,and empirical data

Philosophical Studies - Many philosophers think that a necessary condition on moral blameworthiness is that the wrongdoer can reasonably be expected to avoid the action for which she is blamed....     

Young adults' partner preferences and parents' in-law preferences across generations,genders, and nations

To examine cultural, gender, and parent–child differences in partner preferences, in eight countries undergraduates (n = 2,071) and their parents (n = 1,851) ranked the desirability of qualities in someone the student might marry. Despite sizable cultural differences—especially between Southeast Asian and Western countries—participants generally ranked kind/understanding (reflecting interpersonal communion) highest, and intelligent and healthy (reflecting mental/physical agency) among the top four. Students valued exciting, attractive partners more and healthy, religious partners less than parents did; comparisons with rankings by youth in 1984 (i.e., from the parents' generation) suggested cohort effects cannot explain most parent–child disagreements. As evolutionary psychology predicts, participants prioritized wives' attractiveness and homemaker skills and husbands' education and breadwinner skills; but as sociocultural theory predicts, variations across countries/decades in gendered spousal/in-law preferences mirrored socioeconomic gender differences. Collectively, the results suggest individuals consider their social roles/circumstances when envisioning their ideal spouse/in-law, which has implications for how humans’ partner-appraisal capabilities evolved.     

Definition of compassion-evoking images in a Mexican sample

To assemble a calibrated set of compassion-eliciting visual stimuli, 60 clinically healthy Mexican volunteers (36 women, 24 men; M age = 27.5 yr., SD = 2.4) assessed 84 pictures selected from the International Affective Picture System catalogue using the dimensions of Valence, Arousal, and Dominance included in the Self-assessment Manikin scale and an additional dimension of Compassion. Pictures showing suffering in social contexts and expressions of sadness elicited similar responses of compassion. The highest compassion response was reported for pictures showing illness and pain. Men and women differed in the intensity but not the quality of the compassionate responses. Compassion included attributes of negative emotions such as displeasure. The quality of the emotional response was not different from that previously reported for samples in the U.S.A., Spain, and Brazil. A set of 28 pictures was selected as high-compassion-evoking images and 28 as null-compassion controls suitable for studies designed to ascertain the neural substrates of this moral emotion.     

The Rosenberg Self-Esteem Scale: translation and validation in university students

The aim of this study was to translate into Spanish and to validate the Rosenberg Self-Esteem Scale (RSES), completed by 420 university students. Confirmatory factor analysis revealed that the model that best fit the data, both in the total sample and in the male and female subsamples, was the one-factor structure with method effects associated with positively worded items. The results indicated high, positive correlations between self-esteem and the five dimensions of self-concept. The scale showed satisfactory levels of internal consistency and temporal stability over a four-week period. Lastly, gender differences were obtained. These findings support the use of the RSES for the assessment of self-esteem in higher education.     

Prediction of longevity of volunteer service: a basic alternative proposal

A problem for many organizations is the low continuity of volunteers. Diverse theoretical models have been developed to explain sustained volunteerism, but most of these models have focused on the study of welfare volunteerism and not have verified whether their results could be generalized to other types of volunteerism. In this study, we propose a basic model to explain sustained volunteerism in any type of volunteerism. The aim of this study is to examine this basic model empirically in a sample of socio-assistential volunteers and in a sample of environmental volunteers. For this purpose, 290 volunteers completed a questionnaire and subsequently, two telephone follow-ups were carried out to determine whether the volunteers remained in the NGO one year later. The results show that the basic model offers an acceptable explanation of sustained volunteerism in the two types of volunteer samples studied, but it accounted for a low percentage of variance of the duration of service in both samples. Various relevant implications for the practical management of volunteerism in organizations are derived from theses findings.