Effects of chronic cocaine administration on spatial learning and hippocampal spine density in two genetically different strains of rats

Lewis and Fischer-344 rats have been proposed as an addiction model because of their differences in addiction behaviour. It has been suggested that drug addiction is related to learning and memory processes and depends on individual genetic background. We have evaluated learning performance using the eight-arm radial maze (RAM) in Lewis and Fischer-344 adult rats undergoing a chronic treatment with cocaine. In order to study whether morphological alterations were involved in the possible changes in learning after chronic cocaine treatment, we counted the spine density in hippocampal CA1 neurons from animals after the RAM protocol. Our results showed that Fischer-344 rats significantly took more time to carry out test acquisition and made a greater number of errors than Lewis animals. Nevertheless, cocaine treatment did not induce changes in learning and memory processes in both strains of rats. These facts indicate that there are genetic differences in spatial learning and memory that are not modified by the chronic treatment with cocaine. Moreover, hippocampal spine density is cocaine-modulated in both strains of rats. In conclusion, cocaine induces similar changes in hippocampal neurons morphology that are not related to genetic differences in spatial learning in the RAM protocol used here.     

Long-term aversive taste memory requires insular and amygdala protein degradation

Some reports have shown that the ubiquitin-proteasome system (UPS) is necessary to degrade repressor factors to produce new proteins essential to memory consolidation. Furthermore, recent evidence suggests that memory updating also relies on protein degradation through the UPS. To evaluate whether degradation of proteins is part of the cellular events needed for long-term storage of taste aversion, we injected lactacystin--an UPS inhibitor--into the amygdala and/or insular cortex 30 min before the first or second training trials. The results revealed that degradation of proteins in either the amygdala or insular cortex suffices for long-term stabilization of first-time encounter taste aversion. On the other hand, lactacystin applied in the insula, but not in the amygdala, before the second training prevented long-term storage of updated information. Our results support that degradation of proteins by means of the UPS is required every time taste aversion is to be stored in long-term memory.     

Endogenous-like orienting of visual attention in rats

This study investigated the orienting of visual attention in rats using a 3-hole nose-poke task analogous to Posner, Information processing in cognition: the Loyola Symposium, Erlbaum, Hillsdale, (1980) covert attention task for humans. The effects of non-predictive (50% valid and 50% invalid) and predictive (80% valid and 20% invalid) peripheral visual cues on reaction times and response accuracy to a target stimulus, using Stimuli-Onset Asynchronies (SOAs) varying between 200 and 1,200 ms, were investigated. The results showed shorter reaction times in valid trials relative to invalid trials for both subjects trained in the non-predictive and predictive conditions, particularly when the SOAs were 200 and 400 ms. However, the magnitude of this validity effect was significantly greater for subjects exposed to predictive cues, when the SOA was 800 ms. Subjects exposed to invalid predictive cues exhibited an increase in omission errors relative to subjects exposed to invalid non-predictive cues. In contrast, valid cues reduced the proportion of omission errors for subjects trained in the predictive condition relative to subjects trained in the non-predictive condition. These results are congruent with those usually reported for humans and indicate that, in addition to the exogenous capture of attention promoted by both predictive and non-predictive peripheral cues, rats exposed to predictive cues engaged an additional slower process equivalent to human's endogenous orienting of attention. To our knowledge, this is the first demonstration of an endogenous-like process of covert orienting of visual attention in rats.     

Living With HIV/AIDS: A Psychosocial Perspective on Coping With Prejudice and Discrimination1

We examined 2 strategies used by people with HIV (N = 68) to cope with the effects of prejudice and discrimination: hiding of stigma and in‐group identification. In support of the first proposed path, we found that group‐based discrimination enhanced hiding of stigma. This reduces the perception of personal discrimination; and this, in turn, is positively related to well‐being. We also found evidence for a second, more collective path by which those who are HIV‐positive protect their well‐being. Perceived group‐based discrimination was positively associated with in‐group identification, which, in turn, was positively related to collective action intentions and well‐being. The discussion focuses on how well‐being can be protected through both individual‐ and group‐level processes.     

Structural invariance of multiple intelligences, based on the level of execution

The independence of multiple intelligences (MI) of Gardner's theory has been debated since its conception. This article examines whether the one- factor structure of the MI theory tested in previous studies is invariant for low and high ability students. Two hundred ninety-four children (aged 5 to 7) participated in this study. A set of Gardner's Multiple Intelligence assessment tasks based on the Spectrum Project was used. To analyze the invariance of a general dimension of intelligence, the different models of behaviours were studied in samples of participants with different performance on the Spectrum Project tasks with Multi-Group Confirmatory Factor Analysis (MGCFA). Results suggest an absence of structural invariance in Gardner's tasks. Exploratory analyses suggest a three-factor structure for individuals with higher performance levels and a two-factor structure for individuals with lower performance levels.     

Resiliency and Recovery: Lessons From the Asian Tsunami and Hurricane Katrina

Separated by continents and cultures, survivors of the Asian tsunami and Hurricane Katrina share a common bond in their extreme trauma and ensuing struggles. The authors discuss and illustrate core ideas based on the commonalities derived from the experiences of women survivors of these two disasters. Separados tanto por continentes como culturas, los supervivientes del tsunami asiático y el huracán Katrina comparten el vínculo común de su enorme trauma y las dificultades subsiguientes. Los autores discuten e ilustran las ideas fundamentals basándose en las similitudes derivadas a partir de las experiencias de las mujeres que sobrevivieron a ambos desastres.     

Relative Influence of Professional Counseling Journals

The authors used social network analysis of citation data to study the flow of information and relative influence of 17 professional counseling journals. Although the Journal of Counseling & Development ranked very highly in all measures of journal influence, several division journals emerged as key players in the flow of information within the counseling profession. Results highlight the many facets of journal influence and the fallacy of using single measures, such as journal impact factor, to rank professional counseling journals.     

Perceptions of height and self-esteem.

Although no relationship was found between the actual height of 69 young adolescent males and their self-esteem, positive and significant relationships were found between their own, peers', and teacher's perceptions of their height and self-esteem. These results are discussed with reference to the relationship between body morphology, behavior, and personality.     

Psychometric and CT scan measurements in a case of crossed aphasia in a dextral

A case of crossed aphasia with lesion deep to the right supramarginal gyrus was studied to determine (1) if this patient behaved similar to patients with the same lesion site in the left hemisphere, (2) if visuospatial deficits were present, and (3) if the CT scan asymmetries were similar to those of other right-handers. Speech and language skills were similar to those patients with similar lesions in the left hemisphere. Visuospatial and arithmetic deficits were similar to those described after right-hemisphere and left-hemisphere damage. CT scan asymmetries were atypical. These results provide behavioral and neuroradiological confirmation of atypical hemispheric dominance.