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Response monitoring abnormalities have been reported in chronic schizophrenia patients, but it is unknown whether they predate the onset of psychosis, are present in early stages of illness, or are late-developing abnormalities associated with illness progression. Response-synchronized event-related potentials (ERP) recorded during a picture-word matching task yielded error-related negativity (ERN), correct-response negativity (CRN), and error positivity (Pe) from 84 schizophrenia patients (SZ), 48 clinical high risk patients (CHR), and their age-matched healthy controls (HC; n = 110 and 88, respectively). A sub-sample of 35 early illness schizophrenia patients (ESZ) was compared to 93 age-matched HC and the CHR patients (after statistically removing the effects of normal aging). Relative to HC, 1) SZ, ESZ, and CHR had smaller ERNs, and 2) SZ and ESZ had larger CRNs and smaller Pes. Within the SZ, longer illness duration was associated with larger CRNs but was unrelated to ERN or Pe. CHR and ESZ did not differ on ERN or CRN, although Pe was smaller in ESZ than CHR. These results indicate that while ERN, CRN, and Pe abnormalities are present early in the illness, only the ERN abnormality is evident prior to psychosis onset, and only the CRN abnormality appears to worsen progressively over the illness course. Brain regions subserving response monitoring may be compromised early in the illness and possibly during its clinical prodrome.  相似文献   
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Little empirical knowledge about unemployed adults exists during a time when this group needs substantial career assistance. Because there is greater empirical understanding of college student career development compared with what is known about unemployed adults, a chi square and analyses of covariance were used to compare the career thinking, self‐efficacy, and interests of 169 unemployed adults seeking public job center assistance with that of 200 college students. Additionally, a diverse sample of 2,444 unemployed adults is demographically reviewed. Unemployed adults reported a higher level of Realistic interests and similar levels of negative career thinking and career decision‐making self‐efficacy compared with college students.  相似文献   
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This article argues for two related theses. First, it defends a general thesis: any kind of necessity, including metaphysical necessity, can only be known a priori. Second, however, it also argues that the sort of a priori involved in modal metaphysical knowledge is not related to imagination or any sort of so‐called epistemic possibility. Imagination is neither a proof of possibility nor a limit to necessity. Rather, modal metaphysical knowledge is built on intuition of philosophical categories and the structures they form.  相似文献   
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The study compared clinical, psychopathological, and personality profiles between immigrants and Spanish native-born pathological gambling patients. A total of 1,601 native-born and 133 immigrant patients attending treatment at a specialized hospital unit were administered a battery of questionnaires during clinical assessment. Outcome measures were compared between both groups and the incremental predictive accuracy of the area of origin was examined using a regression model. Native-born Spaniards showed a mean 2.6 yr. greater duration of the disorder, while immigrants scored higher on South Oaks Gambling Screen, frequency of going to casinos, and total money spent (in a single day and/or to recover losses). General psychopathology and personality scores did not differ between the cohorts. However, immigration from Asia had a statistically significantly incremental validity for pathological gambling in South Oaks Gambling Screen scores. Both cohorts shared more similarities than differences in their gambling profiles.  相似文献   
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This longitudinal study among ethnic migrants from Russia to Finland (N = 127) examined the relationships between anticipated and perceived discrimination, ethnic and national identities, and outgroup attitudes towards the national majority group. The study included one pre‐migration and two post‐migration assessments. First, associations between the variables studied were tested using a conventional autoregressive sample‐level modelling approach. Second, individual trajectories and the associations between the individual‐level changes in the variables included in the models were tested. Although there were no sample‐level effects over time, there were significant relationships between changes in discrimination and changes in identification and outgroup attitudes at the individual level. The results indicated that changes in perceived discrimination were not reflected in increased ethnic identification. However, participants who perceived higher levels of discrimination after migration than they anticipated before migration were, in the post‐migration stage, more likely to disidentify from and to increasingly show negative attitudes towards the national majority group. The study complements previous research by examining the identity and attitudinal reactions to perceived ethnic discrimination starting from the pre‐migration stage and highlights the value of incorporating both group and individual perspectives to the research on perceived discrimination. Copyright © 2012 John Wiley & Sons, Ltd.  相似文献   
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