Intra-amygdala ZIP injections impair the memory of learned active avoidance responses and attenuate conditioned taste-aversion acquisition in rats

We have investigated the effect of protein kinase Mzeta (PKMζ) inhibition in the basolateral amygdala (BLA) upon the retention of a nonspatial learned active avoidance response and conditioned taste-aversion (CTA) acquisition in rats. ZIP (10 nmol/μL) injected into the BLA 24 h after training impaired retention of a learned avoidance-jumping response assessed 7 d later when compared with control groups injected with scrambled-ZIP. Nevertheless, a retraining session applied 24 h later indicated no differences between the groups. Additionally, a similar ZIP injection into the BLA during the conditioned stimulus-unconditioned stimulus (CS-US) interval attenuated CTA acquisition. These findings support the BLA PKMζ role in various forms of memory.     

Contribution of the parafascicular nucleus in the spontaneous object recognition task

The parafascicular (PF) nucleus, a posterior component of the intralaminar nuclei of the thalamus, is considered to be an essential structure in the feedback systems of basal ganglia–thalamo-cortical circuits critically involved in cognitive processes. The specific role played by multimodal information encoded in PF neurons in learning and memory processes is still unclear. We conducted two experiments to investigate the role of the PF in the spontaneous object recognition (SOR) task. The behavioral effects of pretraining rats with bilateral lesions of PF with N-methyl-D-aspartate (NMDA) were compared to vehicle controls. In the first experiment, rats were tested on their ability to remember the association immediately after training trials and in the second experiment after a 24 h delay. Our findings provide evidence that PF lesions critically affect both SOR tests and support its role in that non-spatial form of relational memory.     

A confirmatory factor analysis of the "Autoconcepto Forma 5" questionnaire in young adults from Spain and Chile

The aim of this work is to examine the pentafactorial validity of the AF5 Self-Concept Questionnaire in Spanish and Chilean young adults. From the responses of a total of 4,383 young adults aged 17 to 22 years (1,918 Spanish, 44%, and 2,465 Chilean, 56%) it was analyzed the reliability of the instrument, the compared validity of the 5 oblique factor model proposed by the authors versus the unifactorial and the orthogonal alternative models, and was studied the invariance of one Chilean sample. The results of confirmatory factor analyses supported the authors' pentafactorial model. The multi-group factorial invariance showed that Chilean sample of the AF5 does not change neither the Spanish factor weights, nor the variances and covariances of the factors, or the error variances of items. Finally, the internal consistency of the five scales was good in the samples of both countries.     

Constructing Situations and Time

Situations serving as partial worlds as well as events in natural language semantics are constructed from a type-theoretic interpretation of first-order formulae and (after a type reduction) temporal formulae. Limitations of the Russell-Wiener-Kamp derivation of time from events are discussed and overcome to give a more widely applicable account of temporal granularity. Finite situations are formulated as strings of observations, conceptualized to persist inertially (in the absence of forces).     

Brain dynamics associated with face-naming and the tip-of-the-tongue state

Active brain areas and their temporal sequence of activation during the successful retrieval and naming of famous faces (KNOW) and during the tip-of-the-tongue (TOT) state were studied by means of low resolution electromagnetic tomographic analysis (LORETA) applied to event-related potentials. The results provide evidence that adequate activation of a neural network during the first 500 ms following presentation of the photograph--mainly involving the posterior temporal region, the insula, lateral and medial prefrontal areas and the medial temporal lobe--is associated with successful retrieval of lexical-phonological information about the person's name. Significant differences between conditions were observed in the 538-698-ms interval; specifically there was greater activation of the anterior cingulate gyrus (ACC) towards the supplementary motor area (SMA) in the KNOW than in the TOT condition, possibly in relation to the motor response and as a consequence of the successful retrieval of lexical-phonological information about the person.     

A model of the effects of child sexual abuse on post-traumatic stress: the mediating role of attributions of blame and avoidance coping

Employing structural equation modeling, the direct and indirect effects of the severity of Child Sexual Abuse (CSA), attributions of blame for the abuse, and coping strategies on Post-traumatic Stress Disorder (PTSD) symptomatology are analyzed. The effects of other types of child maltreatment on PTSD were also controlled. The sample comprised 163 female college students who were victims of CSA. The results suggested that victims of more severe abuse showed higher levels of avoidant coping, self blame, and family blame. Having suffered other kinds of abuse or neglect was also related to higher family blame attributions. Lastly, both attributions of blame scales were indirectly related to PTSD symptomatology through avoidant coping. The strong relationships between attributions of blame, coping strategies, and PTSD suggest that it might be useful to intervene early with children who have suffered CSA in an effort to modify the attributions they make about the abuse and the way they cope with it.     

Factor structure analysis of the Preschool and Kindergarten Behavior Scale scores in Spanish population

Social competence and antisocial behavior in children are interesting variables for researchers and educators. Nonetheless, there are few assessment instruments capable of measuring the two constructs in small children. The aim of this study is to verify the structural validity of the Preschool and Kindergarten Behavior Scale for Teachers and Caregivers (PKBS-2), in order to determine the theoretical model that best fits the data from a Spanish sample. 1509 children from preschool education (741 males and 768 females) from 3 to 6 years old (M= 3.78; SD= 0.815) participated in the study. Data was analyzed using the Statistical Package for the Social Sciences (SPSS-15.0) and the Structural Equations Program (EQS 6.1). The resulting models of social skills and behavioral problems show adequate fit indexes, statistically significant loadings, and a high internal consistency index (Cronbach's alpha). Lastly, the structural model confirms a two-factor structure: a first factor of Social Skills, comprising three variables (social cooperation, social interaction, and social independence), and a second factor of Behavior Problems, comprising two variables (externalization and internalization of problems).     

Perception of suffering and compassion experience: brain gender disparities

Compassion is considered a moral emotion related to the perception of suffering in others, and resulting in a motivation to alleviate the afflicted party. We compared brain correlates of compassion-evoking images in women and men. BOLD functional images of 24 healthy volunteers (twelve women and twelve men; age=27±2.5 y.o.) were acquired in a 3T magnetic resonance scanner while subjects viewed pictures of human suffering previously verified to elicit compassion and indicated their compassionate experience by finger movements. Functional analysis revealed that while women manifested activation in areas involved in basic emotional, empathic, and moral processes, such as basal regions and cingulate and frontal cortices, activation in men was restricted mainly to the occipital cortex and parahippocampal gyrus. These findings suggest that compassion and its moral elements constitute gender-relative subjective phenomena emerging from differently evolved neural mechanisms and socially learned features possibly related to nurturing skills.     

On the Meaning of Screens: Towards a Phenomenological Account of Screenness

This paper presents a Heideggerian phenomenological analysis of screens. In a world and an epoch where screens pervade a great many aspects of human experience, we submit that phenomenology, much in a traditional methodological form, can provide an interesting and novel basis for our understanding of screens. We ground our analysis in the ontology of Martin Heidegger's Being and Time [1927/1962], claiming that screens will only show themselves as they are if taken as screens-in-the-world. Thus, the phenomenon of screen is not investigated in its empirical form or conceptually. It is rather taken as a grounding intentional orientation that conditions our engagement with certain surfaces as we comport ourselves towards them “as screens.” In doing this we claim to have opened up the phenomenon of screen in a new and meaningful way.