谈伦理审查质量

针对伦理审查质量的含义进行了深入的剖析,对伦理审查质量体系的各个要素,包括法规框架,人员资质、独立性、管理和资源、审查工作的一致性和可预见性、明晰的职责流程等进行了逐一解释,同时提出质量管理环节中建立伦理委员会的内部评估机制,并定期进行独立于伦理委员会的第三方评估的重要意义.     

Age-Related Differences in Cued Recall: Effects of Support at Encoding and Retrieval

The literature is unclear about the relative contributions of environmental supporting conditions to younger and older adults’ episodic memory performance. The work reported addresses the conditions under which different support patterns are obtained. In three experiments, younger and older adults learned picture-word pairs and were then tested with a cued-recall task. Supportive conditions included semantic relations between the pair members (all experiments), and first-letter cues for the target words at retrieval (Experiments 2 and 3). Results of the three experiments indicated different patterns of support for younger and older adults, depending on the number and location of the supporting conditions used. These different patterns are in line with the suggestion that whereas younger adults benefit substantially from support at encoding only, older adults require support at both encoding and retrieval. Alternative accounts of the results are also discussed.     

An Examination of the Latent Structure of the Difficulties in Emotion Regulation Scale

The Difficulties in Emotion Regulation Scale (DERS; Gratz and Roemer, Journal of Psychopathology and Behavioral Assessment 26:41?C54, 2004) is a popular multidimensional self-report measure of emotion regulation. The present study sought to examine the latent factor structure of the DERS. An examination of latent factor intercorrelations and a higher-order confirmatory factor analysis (CFA) suggested that the DERS-AWARENESS dimension may not represent the same higher-order emotion regulation construct as the other five DERS dimensions. Furthermore, findings supported the adequacy of a revised five-factor model of the DERS in which the AWARENESS dimension was removed. This revised DERS total scale did not diminish concurrent relations between the DERS and outcomes relevant to the emotion regulation domain (i.e., depression, anxiety, posttraumatic stress symptoms). Implications for the conceptualization and assessment of emotion regulation are discussed.     

Confabulation in Alzheimer's disease.

Confabulation is present when memory is disturbed, but does it occur in Alzheimer's disease (AD) where memory abnormalities are often severe? In this study, confabulation was assessed prospectively in 26 AD patients and 15 normal elderly (NE) controls using a neuropsychological battery specifically designed to assess different types of memory errors. The results indicated that the AD group made significantly more verbal intrusions than the NE group. These findings provide evidence for the feasibility of eliciting confabulatory-type behavior during clinical assessment and support previous reports which have documented verbal intrusions as a common accompaniment of the memory impairment manifested by AD patients.