Blocking cholesterol synthesis impairs acquisition of the classically conditioned eyeblink response.

Smith-Lemli-Opitz (SLO) syndrome is a congenital disorder characterized by severe mental retardation. Patients with SLO lack 7-dehydrocholesterol (7 dH) reductase, which catalyzes the last step of cholesterol synthesis. Administration of an agent that blocks 7 dH cholesterol reductase, BM 15.766 (BM), leads to a biochemical profile which resembles that of SLO patients, i.e., lower plasma, liver, and brain cholesterol levels accompanied by the appearance of the precursors 7 dH and 8 dH cholesterol. In this article we address the functional consequences of chronic BM treatment on new motor learning by assessing acquisition of the classically conditioned eyeblink response. Just-weaned rats were fed BM by gavage for four months, with half of these rats given exogenous cholesterol during the last two months of BM treatment. Acquisition of the eyeblink response was impaired in BM-treated rats. Impaired acquisition of the eyeblink response was not accompanied by alterations in responsiveness to either the conditioned or unconditioned stimulus. Exogenous cholesterol, a clinically relevant countertreatment, failed to correct for the learning impairment produced by BM treatment. Chronic treatment with a cholesterol synthesis-blocking agent impaired associative learning in just-weaned rats.     

“华人工作相关人格量表”的编制、意义与效度

该文介绍了“华人工作相关人格量表”及其意义、结构、效度的一系列研究。ＣＰＷ选取与人工作相关人格特点有关的题目,在传统人格维度的基础上,增加了服务了取向（ＣＳＯ）和管理才能（ＯＭＲ）这两个针对工作民表境的人格维度。信度分析表明了１５个量表都具可接受内部一致性信度,１５个ＣＰＷ量表分数与一个形容词检测表的相关分析结果支持了ＣＰＷ的内容效度,ＣＰＷ的相关矩阵和因素结构初步确证了ＣＰＷ的结构效度,进一步的     

人机交互过程中认知负荷的综合测评方法

设计模拟网络引擎搜索和心算双任务实验,分析主观评定、绩效测量和生理测量三类评估指标对认知负荷变化的敏感性;采用因素分析、BP神经网络和自组织神经网络三种建模方法,探索人机交互过程中认知负荷的综合评估建模方法。结果显示：心理努力、任务主观难度、注视时间、注视次数、主任务反应时、主任务正确率6个指标对认知负荷变化敏感;采用多维综合评估模型对双任务作业认知负荷进行测量总体上比采用单一评估指标的测量更为有效。BP网络和自组织神经网络两种神经网络模型对认知负荷的测量结果优于传统的因素分析方法     

Leadership predictors of innovation and task performance: Subordinates' self‐esteem and self‐presentation as moderators

This study examined self‐related subordinate variables as moderators of relationships between supervisors' leadership behaviours (transformational as well as active‐corrective transactional leadership) and subordinates' innovative behaviour and task performance. Based on behavioural plasticity and self‐monitoring theory, we hypothesized that these associations would be moderated by subordinates' organization‐based self‐esteem and by their propensity to modify self‐presentation, a major facet of the self‐monitoring construct. Field survey data (N=161) collected in research and development, marketing and human resources departments of several German companies revealed that transformational leadership positively predicted both criteria, whereas active‐corrective transactional leadership negatively predicted innovation. As hypothesized, transformational leadership related more strongly and positively to innovation for subordinates low in organization‐based self‐esteem. When subordinates were low in self‐presentation propensity, active‐corrective transactional leadership was negatively, and transformational leadership was positively associated with task performance.     

初中生自尊的认知加工偏向效应研究

探讨了初中生自尊的认知加工偏向效应。结果发现：高自尊初中生对积极词具有显著的注意偏向效应,低自尊初中生对积极词和消极词均不存在注意偏向效应;当对比图片为高兴－生气或高兴－中性表情时,高自尊初中生对高兴表情均存在显著的注意偏向效应,当对比图片为高兴－生气时,低自尊初中生对生气表情产生明显的注意偏向效应;高自尊组与低自尊组初中生分别对与自我有关的正向、负向形容词存在显著的记忆偏向效应。     

权利、义务、责任的内涵探讨

麦金太尔认为权利概念15世纪才出现,并怀疑以往是否存在自然权利;米尔恩则认为人类社会早就存在与权利相关的事实以及相应的权利意识。康德从权利、责任、义务的内在关系上揭示了权利概念的本质内涵,奠定了权利的道德价值基础。康德的思想存在不足,在理性与普遍形式理论两方面受到了非理性和历史主义的挑战。这些讨论有利于人们对权利、义务、责任本质内涵的深入理解。     

道家道德的普世情怀

Daoism has often been misunderstood as moral nihilism or anti-moralism, but the true Daoism indeed adopts a positive attitude towards morality. At the foundation of its universal sentiment is an affirmation of morality. Daoism takes all things as the starting point of its values in moral philosophy, and ziran 自然 (sponstaneously so) as the foundation of its philosophy with the universal commitment. Daoism hopes to use “Dao to create the best environment for survival, and to fulfill individual responsibility for all things in the world. This is a universal and open attitude towards values. The attraction of Daoist universal sentiment is that it takes ziran as its path, and “objectless desire, “unprincipled knowing, “non-coercive action as ways and means to ensure the transfer of the universal value to all things, while ensuring that they realize their true values and make contributions to the whole society.     

初中生的自尊、受益者特征与亲社会行为的关系

以初中一至三年级学生为对象,采用自尊量表（SES）和帮助行为调查问卷进行测查,以探讨自尊、受助者特征对其亲社会行为的影响。结果表明：（1）在社会道德认知和自我意愿层面上,大多数初中生能表现出积极的亲社会性助人趋向,部分学生的行为决策判定具有不一致性;（2）初中生的自尊程度不影响对他人需要的注意、归因以及行为方式的选择,但与帮助行为的价值取向、行为意愿等认知、情感因素有关,能直接影响自主性的亲社会行为;（3）初中生有关潜在受益者特征的某种认知结果及其相应的情感体验,对帮助型亲社会行为趋向有重要影响;（4）初中生的自尊及其所知觉的潜在量益者特征在亲社会行为趋向中交互作用不显著。     

老年人依恋对主观幸福感的影响:孤独感与自尊的中介作用

采用亲密关系经历量表（ECR）、UCLA孤独量表、罗森伯格自尊量表和纽芬兰纪念大学幸福感量表（MUNSH）对311名老年人进行调查,探讨老年人依恋对主观幸福感的影响,以及孤独感和自尊的中介作用。结果发现：（1）孤独感在依恋焦虑对主观幸福感的影响中起部分中介作用,孤独感在依恋回避对主观幸福感的影响中起完全中介作用;自尊在依恋焦虑、依恋回避对主观幸福感的影响中不起中介作用;（2）孤独感、自尊在依恋焦虑、依恋回避对主观幸福感的影响中起链式中介作用。     

“要有创造性”指导语效应及其对创造性教学的启示

“要有创造性”指导语效应（effects of explicit instructions to“be creative”）,是指在创造力测验或实验任务中,明确要求“要有创造性”（be creative）的指导语,能够促进被试的创造性表现的现象。该效应的理论解释主要有最大化表现理论、目标设置理论和注意控制理论。在指导语中对“创造性”作出解释、创造性任务的类型以及被试特征,都会影响“要有创造性”指导语效应的产生。在创造性教学过程中,可以根据“要有创造性”指导语效应发生的机制,从设置创造性目标、根据任务特征施加精细指导、结合学生特征实施个性化教学三个方面,设计创造性活动,以促进学生创新能力的发展。