On the Ethics of Facial Transplantation Research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements usually applied to health care research. We summarize the achievements of transplant surgery to date, focusing in particular on the safety and efficacy of immunosuppressive medications. We also emphasize the importance of risk/benefit assessments that take into account the physical, aesthetic, psychological, and social dimensions of facial disfiguration, reconstruction, and transplantation. Finally, we maintain that the time has come to move facial transplantation research into the clinical phase.     

Equality,its Basis and Moral Status: Challenging the Principle of Equal Consideration of Interests

The principle of equal consideration of interests (ECOI) is a very popular principle in animal ethics. Peter Singer employs it to ground equal treatment and solve the problem of the basis of equality, namely the problem of why we should grant equal treatment despite the variability of people’s features. In this paper, I challenge Singer’s argument because ECOI does not provide plausible grounds to presume that the interests of diverse individuals are actually equal. Analyzing the case of pain and the interest in not suffering in particular, I contend that there are some insurmountable epistemic and axiological problems in accounting for the equality of interests. Besides criticizing ECOI as a basis of equality, I argue that we need to rely on an equality of moral status. I conclude by providing some considerations on the relation between equality and the principle of proportionality.     

Toward A New Eternalist Paradigm for Afterlife Studies: The Case of the Near-Death Experiences Argument

In contemporary Western culture, death has been widely censured because of its conceptual implications; it lies at the boundaries between reductionism and metaphysics. There is not yet an efficacious epistemology able to solve this contraposition and its consequent collision with science and tradition. This article analyzes Near Death Experiences (NDEs) as a prototypical argument in which the two perspectives conflict. Specifically, it analyzes the epistemological antinomies of the ontological representations of death, inhering in passage versus absolute annihilation. Indeed, the NDEs theme permits the examination of the logical contradiction between monistic reductionism and its ontological counterpart to improve the discovery of a new paradigm that integrates the ecological with eternalist views.     

Constructing Images of the Divine: Latent Heterogeneity in Americans’ Impressions of God

How do individuals psychologically organize their images of the divine? Most work on this topic is factor‐analytic in nature, finding that God images vary with respect to love, judgment, and engagement. However, few studies look at how individuals spontaneously combine these divine dimensions into composite images of God. To fill this gap, we subject data from the 2010 Baylor Religion Survey to latent class analysis and find evidence for five depictions of God: (1) a poorly defined, uninvolved deity; (2) a loving, nonjudgmental deity who is engaged with humanity; (3) a nullity or nonentity; (4) a loving deity who is neither judgmental nor engaged with humanity; and (5) a loving deity who is also both judgmental and engaged. We then present evidence that individuals holding these images vary in their denominational background, religious attitudes and behaviors, and general traits. Our findings suggest that individuals may impose not only a dimensional structure on images of the divine, but a categorical one as well.     

Effects of the iodine deficiency on intellectual variables among children

An association between severe iodine deficiency and poor mental development has been found in many studies. We examined the relationship between moderate or mild iodine deficiency and intellectual capacity in order to determine whether problems common to severe iodine deficiency (including mental retardation) also emerge in a more subtle form. We also wished to know whether the classic methodology (comparing iodine-deficient zones with nondeficient zones) is the most adequate, and propose to combine this grouping by zones with urinary iodine presented by individuals in each zone. We measured IQ, manipulative and verbal capacity, attention, visual motor ability and disruptive behaviour, variables that have barely been studied in this kind of investigations. The sample comprised 760 schoolchildren from the province of Jaén (southern Spain). Our results show that children with low levels of iodine intake and with urinary iodine concentration lower than 100 microg/litre had a lower IQ and displayed more disruptive behaviour than children with high levels of the criteria. The other variables were not associated with iodine deficiency.     

Mirror neurons in humans: consisting or confounding evidence?

The widely known discovery of mirror neurons in macaques shows that premotor and parietal cortical areas are not only involved in executing one's own movement, but are also active when observing the action of others. The goal of this essay is to critically evaluate the substance of functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) studies whose aim has been to reveal the presence of a parallel system in humans. An inspection of this literature suggests that there is relatively weak evidence for the existence of a circuit with 'mirror' properties in humans, such as that described in monkeys.     

Effect of fatigue on double pole kinematics in sprint cross-country skiing

The aim of the present study was to examine the effect of fatigue (physiological, mechanical, and muscular parameters) induced by a sprint simulation on kinematic parameters (cycle, phases, and joints angles) of the double pole technique. Eight elite skiers were tested for knee extensor strength and upper body power both before and after a three-bout simulation of sprint racing. They were video analyzed during the final part of the test track of bouts 1 and 3 using a digital camera. Results showed that skiers were in a fatigue state (decrease of the knee extensors voluntary force (-10.4+/-10.4%) and upper body power output (-11.1+/-8.7%) at the end of the sprint. During bout 3, the final spurt and cycle velocities decreased significantly (-7.5+/-12.3%; -13.2+/-9.5%; both p<.05). Angular patterns were only slightly modified between bouts 1 and 3 with trunk, hip, and pole angles being significantly greater for the third bout. The decrease of hip and trunk flexion and the lower inclination of the pole during the poling phase suggested a reduced effectiveness of the force application which could lead to a decrease in the cycle velocity.