Genetics in eating disorders: state of the science

Eating disorders have been viewed as psychiatric illnesses that are strongly influenced by societal pressures towards thinness and attractiveness. Although the environmental context of these disorders must not be neglected, recent research in the area of genetic epidemiology suggests a substantial influence of genetic factors on liability to eating disorders. This review presents a synthesis of current knowledge about genetic factors implicated in the etiology of eating disorders.     

Prism adaptation changes the subjective proprioceptive localization of the hands

Prism adaptation involves a proprioceptive, a visual and a motor component. As the existing paradigms are not able to distinguish between these three components, the contribution of the proprioceptive component remains unclear. In the current study, a proprioceptive judgement task, in the absence of motor responses, was used to investigate how prism adaptation would specifically influences the felt position of the hands in healthy participants. The task was administered before and after adaptation to left and right displacing prisms using either the left or the right hand during the adaptation procedure. The results appeared to suggest that the prisms induced a drift in the felt position of the hands, although the after‐effect depended on the combination of the pointing hand and the visual deviation induced by prisms. The results are interpreted as in line with the hypothesis of an asymmetrical neural architecture of somatosensory processing. Moreover, the passive proprioception of the hand position revealed different effects of proprioceptive re‐alignment compared to active pointing straight ahead: different mechanisms about how visuo‐proprioceptive discrepancy is resolved were hypothesized.     

Beyond Similarities: Cross-Gender and Cross-Orientation Best Friendship in a Sample of Sexual Minority and Heterosexual Young Adults

The research investigates differences between heterosexual (n?=?714) and lesbian and gay men (n?=?386) young adults regarding best friendship patterns, well-being, and social anxiety. Based on data from a paper-pencil survey of 1,100 Italian young adults aged 18 to 26, this study underlines the importance of the best friend in young adults’ psychological adjustment, highlighting patterns of friendship in heterosexual and lesbian and gay men young adults. Overall, the majority of participants declared that they had best friends; in the total sample, significant differences were found between women and men, and between lesbian/gay men participants and heterosexual young adults. Lesbian and gay men participants reported more cross-gender best friendships than heterosexual participants did, as well as more cross-orientation best friendships. Gender differences were found only with regards to cross-gender friendships: gay men reported more cross-gender friendships than lesbians did, while heterosexual females reported a higher percentage of cross-gender best friendship than heterosexual males did. MANOVA analysis, only in the gay and lesbian sample, showed the effect of gender, cross-gender, and cross-orientation on well-being and social anxiety. For the well-being dimension, gay men participants with female best friends reported higher scores. In terms of social anxiety, lesbian and gay young adults with cross-gender and cross-orientation best friends reported lower levels of social anxiety.     

Assessing Expectations: Towards a Toolbox for an Ethics of Emerging Technologies

In recent years, several authors have argued that the desirability of novel technologies should be assessed early, when they are still emerging. Such an ethical assessment of emerging technologies is by definition focused on an elusive object. Usually promises, expectations, and visions of the technology are taken as a starting point. As Nordmann and Rip have pointed out in a recent article, however, ethicists should not take for granted the plausibility of such expectations and visions. In this paper, we explore how the quality of expectations on emerging technologies might be assessed when engaging in a reflection on the desirability of emerging technologies. We propose that an assessment of expectations’ plausibility should focus on statements on technological feasibility, societal usability, and desirability of the expected technology. Whereas the feasibility statement and, to a lesser extent, the usability statements are frequently quite futuristic, the claims on desirability, by contrast, often display a conservative stance towards the future. Assessing the quality of expectations and visions on behalf of emerging technologies requires, then, a careful and well-directed use of both skepticism and imagination. We conclude with a brief overview of the tools and methods ethicists could use to assess claims made on behalf of emerging technologies and improve the ethical reflection on them.     

“This passage can also be read differently …?:” How Jews and Christians censored Hebrew texts in early modern Modena

This article focuses on the impact exerted by the promulgation of the Index of Prohibited Books by Clement VIII in 1596 on the Jews in early modern Modena. In order to explore diverse cultural perspectives among Jews and Christians, it considers how they read, interpreted, and censored controversial passages in the commentary of Rashi (Solomon ben Isaac of Troyes, 1040–1105) on the Pentateuch. It shows parallels between censorship and the expurgation of Hebrew books, as well as the physical ghettoization and expulsion of Jews from Italian cities enacted by Church authorities, on the one hand, and political and cultural negotiations conducted by the Jews themselves, on the other. Just as the city could be protected from Jewish pollution only through the segregation and expulsion of Jews, so too could the Catholic community be effectively shielded from the contamination of Jewish blasphemies only through banning the Talmud and expurgating other Jewish texts. At the same time, Jews developed means of self-vindication, including a straightforward defense of the principal tenets of Judaism and a stratagem of avoiding discussions that referred to the superiority of Jews over Christians in some interpretations of Rashi. These methods enabled Jews to engage in social and political negotiations with Church and ducal institutions.     

“Doubly Mother”: Heterologous Artificial Insemination Between Biological and Social Parenthood: A Single Case Study

In heterologous artificial insemination, the donation of gametes (either sperm or eggs) from a third person allows infertile and same-sex couples to become parents. Therefore, the child is genetically related to one parent, while the other parent is referred to as the social mother or father. This current single case study aimed at investigating this double access to parenthood in a lesbian couple who had two children after heterologous artificial insemination. In this couple, both women delivered one of the two children, so that each partner is either biological or social mother. The Clinical Generational Interview was used to assess the quality of family relationships, with a specific focus on three dimensions: the origins of each partner, the constitution of the couple, and the generational passage. Paper and pencil textual analysis was conducted following the principles of Interpretative Phenomenological Analysis and led to the identification of six dominant themes (and subthemes): (a) relationship with the family of origin; (b) couple relationship; (c) generational passage; (d) heterologous artificial insemination and “double motherhood”; (e) donor/biological father; and (f) children identity and the disclosure of their origin. This study’s findings revealed the importance of using research techniques aimed at in-depth exploration of this phenomenon consistently with the specificities of the new filiation forms. The adoption of a transgenerational perspective allows articulating conception coordinates with the history of the couple and each partner’s origins.