Shape, orientation, and apparent rotational motion

Apparent rotational motion was investigated in polygonal shapes ranging in rotational symmetry from random to self-identical under 180 degrees rotation. Observers adjusted the rate of alternation between two computer-displayed orientations of any given polygon to determine the point of breakdown of perceived rigid rotation between those two orientations. For asymmetric polygons, the minimum stimulus-onset asynchrony yielding apparent rigid rotation increased approximately linearly with orientational disparity, as anticipated on the basis of the extension of Korte's third law to rotational motion by Shepard and Judd. For nearly symmetric polygons, however, the critical time increased markedly as the disparities approached 180 degrees, owing to the availability of a shorter, nonrigid rotation in the opposite direction. The results demonstrate the existence of competing mental tendencies to preserve the rigid structure of an object and to traverse a minimum transformational path.     

Positive crossover: Parent perceived partner responsiveness and health of youth with asthma

Romantic relationship functioning has implications that extend beyond the romantic dyad. This study tests whether a key positive aspect of relationships, perceived partner responsiveness, can cross over from parents' romantic relationships to children's health and well-being via parenting behavior. In a sample of 112 youth with asthma and their primary caregivers, when caregivers perceived higher partner responsiveness in their romantic relationship, youth experienced improved self-reported asthma symptoms, pulmonary functioning, and positive affect. The associations were robust while controlling for parents' relationship conflict and other relevant covariates, except for the pulmonary functioning outcome, which was instead predicted by parents' conflict. However, parenting behavior (i.e., positive and negative parenting) did not appear to mediate these links. This work highlights the importance of positive romantic relationship processes for youth health and well-being, emphasizing the relevance of clinical intervention work and the need to continue investigating mechanisms through which these processes may be linked.     

The predictive power of combined neuropsychological measures for attention-deficit/hyperactivity disorder in children.

The present study explores the predictive power of seven neuropsychological assessment tools used in combination in classifying children with attention-deficit/hyperactivity disorder (ADHD). Twenty-one ADHD boys and 22 community control children participated. Group differences were significant on the continuous performance test only; however, battery analysis did increase overall predictive power, which was moderate. This study highlights the difficulty in identifying consistent mean differences on tests of frontal/executive functioning across studies, as well as the need to assess the predictive validity of these tests in classifying children with ADHD. The study suggests that these tests may provide greater predictive validity when used in combination. Inconsistencies in the literature are discussed, with consideration of research methodology, the heterogeneity of the ADHD population, and comorbid diagnoses.     

Ethically Allocating COVID-19 Drugs Via Pre-approval Access and Emergency Use Authorization

Abstract

Allocating access to unapproved COVID-19 drugs available via Pre-Approval Access pathways or Emergency Use Authorization raises unique challenges at the intersection of clinical care and research. In conditions of scarcity, prioritization approaches should minimize harm, maximize benefit, and promote fairness. To promote continued data collection, patients seeking access to unproven COVID-19 drugs should receive lower priority for allocation when they decline to participate in clinical trials, either of the requested drug or other investigational products, offering a comparable balance of risks and benefits; special attention should be paid to concerns of voluntariness and distrust. In addition, institutional treatment protocols that can contribute more robust real world data should be preferred to single patient requests for access, with priority for inclusion based on traditional clinical allocation criteria relying on available evidence. Fairness demands distribution of these protocols across a diverse range of sites, particularly those serving marginalized populations, among other protections.     

It's what's on the outside that matters: an advantage for external features in children's word recognition

The relative importance of internal and external letter features of words in children's developing reading was investigated to clarify further the nature of early featural analysis. In Experiment 1, 72 6-, 8-, and 10-year-olds read aloud words displayed as wholes, external features only (central features missing, thereby preserving word shape information), or internal features only (central features preserved). There was an improvement in the processing of external features compared with internal features as reading experience increased. Experiment 2 examined the processing of the internal and external features of words employing a forward priming paradigm with 60 8-, 10-, and 12-year-olds. Reaction times to internal feature primes were equivalent to a nonprime blank condition, whereas responses to external feature primes were faster than those to the other two prime types. This advantage for the external features of words is discussed in terms of an early and enduring role for processing the external visual features in words during reading development.     

The role of self-criticism, dependency, and hassles in the course of depressive illness: a multiwave longitudinal study

The current study utilized a multiwave longitudinal design to examine whether dependency and/or self-criticism influence the course of depressive symptoms in a community sample of adults with a history of major depression. In addition, the authors examined whether self-esteem serves as a buffer against the development of depressive symptoms following increases in hassles in individuals possessing such traits. At Time 1, 102 participants completed measures assessing depressive symptoms, self-criticism, dependency, and self-esteem. Every 6 weeks for the next year, participants completed measures assessing depressive symptoms and hassles. High self-criticism was associated with greater elevations in depressive symptoms following elevations in hassles in low but not high-self-esteem individuals. Results with respect to dependency, however, were contrary to hypotheses. High dependency was associated with elevations in depressive symptoms following elevations in hassles in high-self-esteem individuals. In contrast, high dependency was associated with chronically elevated depressive symptoms in low-self-esteem individuals.