Sensorimotor synchronization: motor responses to regular auditory patterns.

Subjects (N = 32) were asked to synchronize a motor response with tones in auditory patterns. These patterns were created from six tones and six intertone intervals of equal duration. The pitch of the first tone differed from the others. It was found that subjects used three types of timing in their motor response: (1) the first intertone interval was prolonged and the second interval was shortened, (2) the second intertone interval was prolonged and the first interval was shortened, and/or (3) the first interval and the second interval were of approximately the same length. The prolongation of the fifth interval was observed during all three types of timing. The results are explained using the concept of suprasegmental control of timing, which explains a prolongation of intervals at critical control point of the patterns. The occurrence of three different strategies of timing is discussed in connection with similar principles in musical performance.     

Two-stage model for order discrimination

Ulrich (1987), exploring the shapes of psychometric functions obtained in the ternary-response paradigm, indicated several inconsistencies between observed and predicted relationships providing evidence against most popular models of temporal-order judgment. In this paper, a new model is presented. It assumes that there are two mechanisms involved in the order discrimination task: one is responsible for the recognition of whether or not the stimuli are successive, and the second is able to determine their order. The model was tested using Allan's (1975a, 1975b) and Ulrich's (1987) data; the model predictions were found to be consistent with the experimental results.     

Idea and reality of training analysis. A plea for reforms (II)

Thom? pleads for a form of psychoanalytic training in which the critical appropriation of psychoanalytic and humanistic knowledge as well as therapeutic competence are the focus and in which the personal analysis (super-therapy) is no longer overvalued. It seems possible to limit the length of training analyses. Qualification for professional practice should be worked out exclusively within the training institute and in close collaboration with instructors.     

Impression management in behavior toward handicapped patients]

A previous study (Tr?ster, 1989) showed that nonhandicapped persons preferred a physically handicapped interaction partner to a nonhandicapped partner in an attributionally unambiguous situation. In order to test whether this "sympathy effect of physical handicap" is based on tendencies of impression management, 48 female subjects had to choose to sit next to either a physically handicapped or nonhandicapped female interaction partner in order to view a film together. Attributional ambiguity was varied by either confounding the choice of an interaction partner with a second, socially acceptable alternative (attributionally ambiguous situation: a choice between two films) or not confounding it (attributionally unambiguous situation: no choice between films). Public responsibility was manipulated by informing the subjects about their freedom to choose where they wished to sit either in public (public responsibility) or in private (no public responsibility). The results supported the impression management hypothesis: The handicapped interaction partner (in a wheelchair) was only preferred when the subjects had to anticipate that observers would deduce a preference of the chosen partner from the subjects' choices because of the attributionally unambiguous situation and the public announcement of their freedom of choice. Results suggest that the nonhandicapped strive to exhibit positive and nondiscriminative behavior toward the handicapped in order to avoid creating a disadvantageous impression in an observer.     

Affect and performance in simple problems

We investigate the effects of emotional mood states on solving simple pattern comparison tasks. It is assumed that the effects of mood are mediated through response biases as well as effort expenditure. Departing from these assumptions, trend hypotheses are derived for the response biases evaluated by means of a signal detection analysis, for the response latencies, and for an adequate index of the underlying ability. The data support the hypotheses, and in particular, a positive mood state is found to improve performance. The assumption of mood-dependent differences in effort expenditure provides a parsimonious and integrative account of our results, while a reduced-capacity view cannot explain the findings obtained under positive mood induction.     

The enhancement of retention induced by vasopressin in mice may be mediated by an activation of central nicotinic cholinergic mechanisms.

Immediate post-training subcutaneous administration of lysine vasopressin (LVP, 0.003-1.00 microgram/kg) enhanced retention, whereas the vasopressin antagonist AAVP (0.01-0.30 microgram/kg) impaired it, in male Swiss mice tested 48 h after training in an inhibitory avoidance task. Both effects were dose-dependent. Neither LVP nor AAVP affected response latencies in mice not given the footshock on the training trial. The simultaneous administration of AAVP at a dose (0.01 microgram/kg) which had no effect on retention shifted the dose-response curve of LVP to the right. Nicotine (1.0-30.0 micrograms/kg, sc), a central nicotinic cholinergic agonist, also facilitated retention in a dose-related manner without affecting the retention performance of unshocked mice. The effect of nicotine was prevented by the central acting nicotinic cholinergic receptor antagonist mecamylamine (5 mg/kg, sc.). In contrast, neither hexamethonium (5 mg/kg, sc), a peripheral acting nicotinic receptor blocker, nor atropine (0.5 mg/kg, sc) or methylatropine (0.5 mg/kg, sc), two anticholinergic drugs which are known to act on muscarinic cholinergic receptors, prevented the effect of post-training nicotine. The effects of LVP and nicotine were time-dependent, suggesting that both treatments enhanced retention by influencing post-training processes involved in memory storage. Low doses of nicotine (1.50 microgram/kg, sc) or the central anticholinesterase physostigmine (35 micrograms/kg, sc) and LVP (0.003 microgram/kg, sc), which had no effect on retention when administered alone, produced a synergistic interaction when given together following training. The influence of LVP (0.03 microgram/kg, sc) on retention was prevented not only by AAVP (0.01 microgram/kg, sc) but also by mecamylamine (5 mg/kg, sc), whereas the effects of nicotine (10.0 micrograms/kg, sc) were prevented only by mecamylamine. These results suggest that the enhancement of retention induced by vasopressin is probably due to an activation of central nicotinic cholinergic mechanisms which are critical for memory formation.     

A note on partitioned determinants

A formula for the determinant of a partitioned matrix, possibly with singular submatrices, is derived and applied to some psychometric and numerical problems.     

Generalized eigenvalue problems with positive semi-definite matrices

In a recent paper in this journal McDonald, Torii, and Nishisato show that generalized eigenvalue problems in which both matrices are singular can sometimes be solved by reducing them to similar problems of smaller order. In this paper a more extensive analysis of such problems is used to sharpen and clarify the results of McDonald, Torii, and Nishisato. Possible extensions are also indicated. The relevant mathematical literature is reviewed briefly.     

Evidence that a factor besides progesterone, prolactin, or plasma-estradiol-binding protein inhibits estrogen-induced sexual receptivity in pregnant rats.

Daily administration of estradiol benzoate stimulated significantly less lordotic behavior in rats during the second half of pregnancy than in ovariectomized females that received subcutaneous progesterone implants, pituitary grafts that raised plasma prolactin, or both treatments combined. Following an initial facilitation of receptivity, females with progesterone implants showed only moderate reductions in lordosis quotients over 3 test days. The capacity of plasma from pregnant rats to bind estradiol was found to increase significantly during the second half of pregnancy. However, daily administration to pregnant rats of a synthetic estrogen, R 2858, which is not bound by plasma protein, was no more effective than estradiol benzoate in stimulating receptive behavior. Administration of estradiol benzoate also stimulated significantly lower levels of sexual behavior in pregnant females than in females in which pseudopregnancy had been prolonged by previous hysterectomy or induction of uterine decidualization. These findings suggest that some endocrine factor other than progesterone, prolactin, or estradiol-binding protein is primarily responsible for the potent suppression of behavioral responsiveness to estrogen which occurs in pregnant rats. It is suggested that 5 alpha-reduced androgens may cause these behavioral effects.     

Some problems of Wilson's disease

The Leipzig Center for Wilson's Disease in the GDR is charged with the registration and diagnosis of all homozygous Wilson gene carriers, the clarification of all suspected cases, including the heterozygote test, and the co-ordination of long-term treatment. At present, there are 78 recorded Wilson gene carriers living. On the basis of our own comprehensive observations and investigations over prolonged periods of time, questions concerning pathogenesis, genetics, diagnosis and therapeutic measures, including their side-effects, are dealt with.