Evaluation of a structural polymorphism in the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and the activation of executive attention networks

The specificity of genetic effects on brain activation is a central issue in understanding how molecular actions at the synapse relate to anatomic patterns of brain activity. In an effort to understand the basis for the specificity of gene-associated brain activity, we explore a well-studied genetic polymorphism, TaqIA, which lies downstream of the DRD2 gene in the protein-encoding region of a neighboring gene, ANKK1, which is not expressed in the brain. We utilize the attention network test and find that carriers of the A1 allele show gene-associated functional activation in an anatomically specific, dopamine-rich region of the brain comprising the anterior cingulate gyrus, a finding partially consistent with prior data from functional imaging genetics. A review of the patterns of expression for ANKK1 and DRD2 and the extent of linkage disequilibrium between the two genes sheds light on additional criteria for the selection of candidate genes in imaging-genetic studies.     

Towards a Confucian Virtue Bioethics: Reframing Chinese Medical Ethics in a Market Economy

This essay addresses a moral and cultural challenge facing health care in the People’s Republic of China: the need to create an understanding of medical professionalism that recognizes the new economic realities of China and that can maintain the integrity of the medical profession. It examines the rich Confucian resources for bioethics and health care policy by focusing on the Confucian tradition’s account of how virtue and human flourishing are compatible with the pursuit of profit. It offers the Confucian account of the division of labor and the financial inequalities this produces with special attention to China’s socialist project of creating the profession of barefoot doctors as egalitarian peasant physicians and why this project failed. It then further develops the Confucian acknowledgement of the unequal value of different services and products and how this conflicts with the current system of payment to physicians which has led to the corruption of medical professionalism through illegal supplementary payments. It further gives an account the oblique intentionality of Confucian moral psychology that shows how virtuous persons can pursue benevolent actions while both foreseeing profit and avoiding defining their character by greed. This account of Confucian virtue offers the basis for a medical professionalism that can function morally within a robustly profit-oriented market economy. The paper concludes with a summary of the characteristics of Confucian medical professionalism and of how it places the profit motive within its account of virtue ethics.     

Permitting immoral behaviour: A generalized compensation belief hypothesis

When are we more likely to permit immoral behaviours? The current research examined a generalized compensation belief hypothesis that individuals, as observers, would morally tolerate and accept someone paying forward unfair treatment to an innocent person as a means to compensate for the perpetrator's previously experienced mistreatment. Across five experiments (N = 1107) based on economic games (Studies 1–4) and diverse real-life scenarios (Study 5), we showed that participants, as observing third parties, were more likely to morally permit and engage in the same negative act once they knew about previous maltreatment of the perpetrator. This belief occurred even when the content of received and paid-forward maltreatment was non-identical (Study 2), when the negative treatment was received from a non-human target (Study 3) and when the maltreatment was intangible (e.g. material loss) or relational (e.g. social exclusion; Study 5). Perceived required compensation mediated the effect of previous maltreatment on moral permission (Studies 4 and 5). The results consistently suggest that people's moral permission of immoral behaviours is influenced by perpetrator's previous mistreatment, contributing to a better understanding of the nature and nuances of our sense of fairness and contextualized moral judgement.     

Experiencing Buddhist practices promotes nonbelievers’ preference for future rewards in intertemporal choices

Religious individuals often prefer future rewards more in intertemporal decision-making than nonreligious individuals, but the reasons behind this preference remain under-investigated. Focusing on decision-making in Buddhist culture, the current study aimed to examine three potential mechanisms: Buddhist practices, self-control and belief in future-oriented concepts. In five studies, we consistently found that nonbelievers’ preference ratings for Larger and Later (LL) options increased after visiting a temple (Study 1, n = 99) or participating in Buddha name chanting (Studies 2–5, n = 314). We also found in Studies 3 and 4 that this effect was mediated by the individual's level of self-control, but no evidence was found to support the mediation of belief in future-oriented concepts. These results contribute to the work attesting to the effect of religious practices on individuals (especially nonbelievers). They also provide a mechanism (self-control) for the positive correlation between individuals’ religiousness and preference for future rewards in intertemporal decision-making.     

中美成年人和老年人数学能力发展的比较研究

采用一套心理计量测验考察中美两国青老年被试在算术能力、知觉速度及空间方位能力方面的操作是否有国家间和年龄组间差异,不同领域之间是否有不同的能力模式。测验结果表明：在知觉速度和空间方位测验上,中美青年组的操作成绩均明显超过老年组;在算术能力测验上,中国青年组的成绩仍超过老年组,但美国青老年组间则无明显差异;中国青年组在算术能力测验上成绩优于美国同龄组,在其它两个测验上则无明显差异;在所有能力测验上中美老年组的成绩都无明显差异;总的模式表明,美国青年的算术能力呈逐代下降趋势,中国儿童和青年的算术能力远远超过美国同龄人的状况可能只是个近期的现象。     

目前针灸临床研究存在的问题及对策

针对目前针灸临床研究中存在的系列问题,提出用系统工程的理论和方法加以解决。其对策包括：整体考察与多因素研究;探讨有关因素的主次作用及交互关系;攻克优化组合方案;研究的数学化;加强机能状态与疗效关系的研究;综合研究,系统管理;系统开放,联用它法。同时认为,倡导用包括系统科学在内的自然辨证法的观点和方法指导针灸临床的研究,将促进研究的深化和导致研究质的飞跃。     

Note on construction of an item analysis table for the high-low-27-per-cent group method

This paper describes the construction of a new item analysis table for the high-low-27-per-cent group method. The table provides a ready means of translating the observed proportions of success in the two extreme groups (p _H ,p _L ) into measures of item difficulty and item discrimination (p, Δ, andr). The tabled values of both the difficulty index,p, and the discrimination index,r, have been derived from Karl Pearson's tables of the normal bivariate surface.     

家庭功能与学前儿童行为问题的关系:依恋回避和社交焦虑的多重中介作用

采用纵向的研究设计,对上海市两所公办幼儿园192名学前儿童进行为期一年半的追踪调查,探讨了家庭功能与学前儿童行为问题之间的关系以及依恋回避和社交焦虑的中介作用。结果发现：（1）家庭功能、依恋回避、社交焦虑和儿童行为问题之间存在两两相关;（2）家庭功能能够显著负向预测儿童行为问题;（3）依恋回避和社交焦虑分别在家庭功能和行为问题之间起独立中介作用;（4）依恋回避和社交焦虑在家庭功能和行为问题之间起序列中介作用。研究结果进一步揭示了家庭功能对学前儿童行为问题影响的内在机制。     

突发性危机情景下抢购现象的发生及其应对策略

今年1到4月份,在我国一些地区出现了几次因SARS疫情恐慌导致的抢购风潮,其特点主要表现为突发性、群发性和快速平息的短暂性。这些特点与人们的风险认知机制有关。研究表明,情绪唤醒抑制人类认知中的控制性加工部分,但对自动化加工部分起促进作用。人们在危机情景下的快速应对行为主要是自动化的,事前培训和行为习惯决定了自动化反应的策略和方式。由于口传信息的高情绪唤醒水平和操作上的方便易行,恐慌性抢购便被引发出来。     

工作记忆、表达方式和同质性对线性三段论推理影响的眼动研究

采用眼动记录法,探讨了工作记忆、两个前提间的关系以及表达方式对线性三段论推理的影响。本实验采用2（表达方式：肯定、否定）×2（前提间的关系：同质、不同质）×2（工作记忆容量：高、低）的混合设计。通过分析总注视时间、第一次注视时间、第二次注视时间和回视,发现线性三段论推理过程既有语言加工的参与又有表象加工的参与。推理过程中的语言表征过程和空间关系的建立都受到工作记忆容量的影响,被试的工作记忆容量越高,就越容易建立语言表征和空间的关系。