Hypoxic adaptation during development: relation to pattern of neurological presentation and cognitive disability

Children with acute hypoxic-ischaemic events (e.g. stroke) and chronic neurological conditions associated with hypoxia frequently present to paediatric neurologists. Failure to adapt to hypoxia may be a common pathophysiological pathway linking a number of other conditions of childhood with cognitive deficit. There is evidence that congenital cardiac disease, asthma and sleep disordered breathing, for example, are associated with cognitive deficit, but little is known about the mechanism and whether there is any structural change. This review describes what is known about how the brain reacts and adapts to hypoxia, focusing on epilepsy and sickle cell disease (SCD). We prospectively recorded overnight oxyhaemoglobin saturation (SpO2) in 18 children with intractable epilepsy, six of whom were currently or recently in minor status (MS). Children with MS were more likely to have an abnormal sleep study defined as either mean baseline SpO2 <94% or >4 dips of >4% in SpO2/hour (p = .04). In our series of prospectively followed patients with SCD who subsequently developed acute neurological symptoms and signs, mean overnight SpO2 was lower in those with cerebrovascular disease on magnetic resonance angiography (Mann-Whitney, p = .01). Acute, intermittent and chronic hypoxia may have detrimental effects on the brain, the clinical manifestations perhaps depending on rapidity of presentation and prior exposure.     

Firstborn preference and attitudes toward using sex selection technology

The authors investigated sex preferences for firstborn children and (a) pro- technology attitudes and willingness to use sex selection technology (SST) and (b) social conformity. College students (N = 469; 239 women, 230 men) answered demographic questions and questions on technology usage and personal preferences and completed a measure of conformity. Findings revealed a significant overall preference for firstborn males, a specific preference of potential SST users for firstborn sons, and a greater willingness of African American students, compared with White students, to use SST. No correlation was found between conformity and potential SST use. Logistic regression results suggested that protechnology attitudes may be predictive of firstborn preferences. Implications of the findings are discussed in relation to gender equality and population sex ratios.     

Visual statistical learning in infancy: evidence for a domain general learning mechanism

The rapidity with which infants come to understand language and events in their surroundings has prompted speculation concerning innate knowledge structures that guide language acquisition and object knowledge. Recently, however, evidence has emerged that by 8 months, infants can extract statistical patterns in auditory input that are based on transitional probabilities defining the sequencing of the input's components (Science 274 (1996) 1926). This finding suggests powerful learning mechanisms that are functional in infancy, and raises questions about the domain generality of such mechanisms. We habituated 2-, 5-, and 8-month-old infants to sequences of discrete visual stimuli whose ordering followed a statistically predictable pattern. The infants subsequently viewed the familiar pattern alternating with a novel sequence of identical stimulus components, and exhibited significantly greater interest in the novel sequence at all ages. These results provide support for the likelihood of domain general statistical learning in infancy, and imply that mechanisms designed to detect structure inherent in the environment may play an important role in cognitive development.     

Remembering the good, forgetting the bad: intentional forgetting of emotional material in depression

The authors examined intentional forgetting of negative material in depression. Participants were instructed to not think about emotional nouns that they had learned to associate with a neutral cue word. The authors provided participants with multiple occasions to suppress the unwanted words. Overall, depressed participants successfully forgot negative words. Moreover, the authors obtained a clear practice effect. However, forgetting came at a cost: Compared with the nondepressed participants and with the depressed participants who were instructed to forget positive words, depressed participants who were instructed to forget negative words showed significantly worse recall of the baseline words. These results indicate that training depressed individuals in intentional forgetting could prove to be an effective strategy to counteract automatic ruminative tendencies and mood-congruent biases.     

Stereotype distinctiveness: how counterstereotypic behavior shapes the self-concept

Three experiments examined the relationship between distinctiveness and self-schematicity. Experiment 1 revealed that people were more likely to be self-schematic in domains of strong performance when they felt distinct from family and peers in those domains. Experiments 2 and 3 extended this finding into the arena of stereotypes by demonstrating that people were more likely to be self-schematic in domains of strong performance when their performance was counterstereotypic rather than stereotypic. In particular, African Americans and women were more likely to be schematic for intelligence than Caucasians and men if they performed well academically, whereas Caucasians-especially men-were more likely than African Americans to be schematic for athletics if they performed well athletically. These results suggest that counterstereotypic behavior plays a uniquely powerful role in the development of the self-concept.     

Do Promise Keepers Dream of Feminist Sheep?

This article describes a qualitative researchstudy of Promise Keeper fathers. Twenty-two middleclass, primarily White suburban fathers were interviewedin focus groups abouttheir fathering experiences. The grounded theory analysis found that the menwere experiencing gender role strain as they tried toconform to traditional masculine role norms. The PromiseKeeper movement provided them with an ideology and social supportsystem that facilitated theirbecoming more involved fathers, while simultaneouslyreassuring them that they were the leaders of theirfamilies. Using these supports, the men were able to construct a more personally gratifyingfatherhood identity. These results suggest a possibleinterpretation of why the Promise Keeper movement hasappealed to more men than has the pro-feminist men's movement.     

Aging, exercise, and attention.

The authors investigated the relationship among aging, attentional processes, and exercise in 2 experiments. First they examined age differences on 2 attentional tasks, a time-sharing task and an attentional flexibility task. Young adults alternated attention between 2 sequenced tasks more rapidly and time-shared the processing of 2 tasks more efficiently than older adults. They then investigated the effects of aerobic exercise on the same 2 attentional tasks in older adults. Following the 10-week exercise program, older exercisers showed substantially more improvement in alternation speed and time-sharing efficiency than older controls. Interestingly, this exercise effect was specific to dual-task processing. Both groups of subjects showed equivalent effects on single-task performance. These results indicate that aerobic exercise can exert a beneficial influence on the efficiency of at least 2 different attentional processes in older adults.     

IS SOCIAL VALIDITY WHAT WE ARE INTERESTED IN? ARGUMENT FOR A FUNCTIONAL APPROACH

It is argued that neither the term social nor the term validity is best to identify the processes used or the results obtained in questioning consumers about the goals set, procedures employed, or outcomes achieved in habilitative programming. The term consumer satisfaction acknowledges the fact that it is essentially a collection of consumer opinions. The underlying intent of the process might be called habilitative validation, a name that seems to better guide our validation efforts. More important, in carefully considering consumer satisfaction assessment, it becomes clear that not only does consumer satisfaction itself need to be validated, but also that more objective methods can be used for assessing habilitative validity. However, legitimate uses still remain for consumer satisfaction measurement, as long as we do not mistake it for strong evidence of the habilitative validity of our goals, procedures, or outcomes.     

Decision support systems effectiveness: Conceptual framework and empirical evaluation

Decision Support Systems (DSS) are designed to help human beings in solving problems more efficiently or making better decisions. While an increasing number of DSS have been and are developed, the effectiveness of such systems has not yet been demonstrated. This study proposes a conceptual framework for measuring the effectiveness of DSS and reports the results of a before-and-after study designed to compare two experimental groups of problem solvers assisted by one of two technologies for conflict resolution with a control group without any technology. The two technologies that are examined in this paper consist of a computerized DSS for conflict resolution, Resolve(!), and a videotape on conflict resolution, Video. Various measures of the problem solving episode were recorded, including both process and outcome measures. Overall, the groups with access to the technologies perceived a significantly better resolution of the problem they addressed than their control group counterpart. The two technologies differed essentially on two out of 11 variabales: subjects assigned to the computerized DSS technology generated more alternative solutions to the problem they tried to solve and reported a higher perceived progress in the resolution of the problem, than did subjects who were assigned to the videotape technology.